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Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Additionally we are shipping CXCL16 Kits (67) and CXCL16 Proteins (47) and many more products for this protein.
Showing 10 out of 155 products:
Human Monoclonal CXCL16 Primary Antibody for FACS, IF - ABIN2664903
Shimaoka, Nakayama, Fukumoto, Kume, Takahashi, Yamaguchi, Minami, Hayashida, Kita, Ohsumi, Yoshie, Yonehara: Cell surface-anchored SR-PSOX/CXC chemokine ligand 16 mediates firm adhesion of CXC chemokine receptor 6-expressing cells. in Journal of leukocyte biology 2004
Show all 4 references for ABIN2664903
Human Monoclonal CXCL16 Primary Antibody for FACS - ABIN2662702
Shimaoka, Nakayama, Kume, Takahashi, Yamaguchi, Minami, Hayashida, Kita, Ohsumi, Yoshie, Yonehara: Cutting edge: SR-PSOX/CXC chemokine ligand 16 mediates bacterial phagocytosis by APCs through its chemokine domain. in Journal of immunology (Baltimore, Md. : 1950) 2003
Show all 4 references for ABIN2662702
Human Polyclonal CXCL16 Primary Antibody for EIA, IHC (p) - ABIN116405
Gutwein, Abdel-Bakky, Schramme, Doberstein, Kämpfer-Kolb, Amann, Hauser, Obermüller, Bartel, Abdel-Aziz, El Sayed, Pfeilschifter: CXCL16 is expressed in podocytes and acts as a scavenger receptor for oxidized low-density lipoprotein. in The American journal of pathology 2009
Show all 2 references for ABIN116405
Human Polyclonal CXCL16 Primary Antibody for WB - ABIN2776911
Schramme, Abdel-Bakky, Kämpfer-Kolb, Pfeilschifter, Gutwein: The role of CXCL16 and its processing metalloproteinases ADAM10 and ADAM17 in the proliferation and migration of human mesangial cells. in Biochemical and biophysical research communications 2008
Mouse (Murine) Polyclonal CXCL16 Primary Antibody for IF (p), IHC (p) - ABIN686572
Cottle, Ursino, Ip, Jones, Ditommaso, Hacking, Mangan, Mellett, Henley, Sviridov, Nold-Petry, Nold, Meikle, Kile, Smyth: Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis. in Human molecular genetics 2014
Higher levels CXCL16 may be a biomarker for predicting stroke incidence and might contribute to plaque destabilization.
CXCL16 is released into the circulation as a result of cardiac surgery and that high post-operative CXCL16 levels are associated with an increased severity of post-operative organ dysfunctions.
Serum CXCL16 may be a novel biomarker for the diagnosis of patients with diabetic coronary artery disease.
High CXCL16 expression is associated with prostate cancer.
In conclusion, rheumatoid arthritis synovial fibroblasts were activated by CXCL16 to produce RANKL (show TNFSF11 Antibodies) via pathways involving JAK2 (show JAK2 Antibodies)/STAT3 (show STAT3 Antibodies) and p38/MAPK (show MAPK14 Antibodies)
Our data suggest that CXCL16 induces angiogenesis in autocrine manner via ERK (show EPHB2 Antibodies), Akt (show AKT1 Antibodies), p38 (show CRK Antibodies) pathways and HIF-1alpha (show HIF1A Antibodies) modulation
Cell proliferation enhancing and anti-apoptosis activity requires the intracellular domain and apparently the dimerization of the transmembrane chemokine (show CCL1 Antibodies) ligand.
Wnt5a (show WNT5A Antibodies)-Ror2 (show ROR2 Antibodies) signaling enhances expression and secretion of CXCL16 in mesenchymal stem cells thereby activating CXCR6 (show CXCR6 Antibodies) expressed on tumor cells to promote proliferation.
Endothelial CXCL16's action on platelets is not limited to platelet activation. Immobilised CXCL16 also acts as a potent novel platelet adhesion ligand, inducing platelet adhesion to the human vessel wall.
HMGB-1, CXCL16, miRNA-30a, and urinary TGF-ss1 were highly expressed in PNS patients and may play important roles in the pathogenesis and development of PNS.
Simvastatin exerts a protective effect on renal function and structure in mice with ADR (show SARS Antibodies) nephropathy which related to the decreasing expression of CXCL16 in glomerular podocytes followed by the decreasing endocytosis of ox-LDL in podocytes and inhibition of NF-kappaB (show NFKB1 Antibodies) pathway activation.
These results indicate that MEK (show MDK Antibodies) inhibitor diminishes Nasopharyngeal carcinoma cell proliferation and NPC (show NPC1 Antibodies)-induced osteoclastogenesis via modulating CCL2 (show CCL2 Antibodies) and CXCL16 expressions.
Serum CXCL16 is increased in severe pancreatitis with infected pancreatic necrosis and identifies patients who benefit from surgical necrosectomy
injured hepatocytes up-regulated CXCL16 expression, indicating that scavenging functions of CXCL16 might be additionally involved in the pathogenesis of NAFLD (show TSC2 Antibodies).
role of IFN-gamma (show IFNG Antibodies), CXCL16, and ADAM10 (show ADAM10 Antibodies) in oxLDL-induced lipid accumulation in glomerular podocytes
CXCL16 suppresses liver metastasis of colorectal cancer by promoting TNF-alpha (show TNF Antibodies)-induced apoptosis by tumor-associated macrophages.
Loss of sst2 (show SSTR2 Antibodies) from pancreatic tissues activates PI3K signaling via AKT (show AKT1 Antibodies), leading to activation of NF-kappaB (show NFKB1 Antibodies), amplification of oncogenic KRAS signaling, increased expression of CXCL16, and pancreatic tumor formation.
CXCL16 was constitutively expressed by CX3CR1 (show CX3CR1 Antibodies)(+) intestinal dendritic cells (DCs) and coexpressed with IL-23 (show IL23A Antibodies) after Citrobacter rodentium infection.
CCL2 (show CCL2 Antibodies) and CXCL16 chemokines produced by tumor-conditioned Gr-1 (show GSR Antibodies)(+)CD11b (show ITGAM Antibodies)(+) myeloid cells synergistically induce angiogenesis in vitro by stimulating the ERK1/2 (show MAPK1/3 Antibodies) signaling pathway.
CXCL16 expression inhibits liver metastasis in a murine model of colorectal cancer.
Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis (By similarity). Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo.
chemokine (C-X-C motif) ligand 16
, small inducible cytokine B14
, C-X-C motif chemokine 16
, CXC chemokine ligand 16
, scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
, small-inducible cytokine B16
, transmembrane chemokine CXCL16
, Cxc chemokine ligand 16
, zinc finger, MYND-type containing 15
, Transmembrane chemokine CXCL16