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Chemokine (C-X-C Motif) Ligand 2 Proteins (CXCL2)

CXCL2 encodes a member of the WD repeat protein family. Additionally we are shipping CXCL2 Antibodies (127) and CXCL2 Kits (115) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CXCL2 114105 P30348
CXCL2 2920 P19875
CXCL2 20310 P10889
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Top CXCL2 Proteins at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag Chemokine (C-X-C Motif) Ligand 2 (CXCL2) (AA 28-100), (full length) protein (His tag) 50 μg Log in to see 9 to 11 Days
$217.80
Details
HOST_Escherichia coli (E. coli) Mouse His tag,SUMO Tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated 100 μg Log in to see 4 to 6 Days
$412.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   10 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   10 μg Log in to see 10 to 12 Days
$190.24
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Log in to see 9 Days
$914.29
Details

CXCL2 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,
,
Human , , ,
, , , ,
Mouse (Murine) ,
, ,

Top referenced CXCL2 Proteins

  1. Mouse (Murine) CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN2666642 : Haskill, Peace, Morris, Sporn, Anisowicz, Lee, Smith, Martin, Ralph, Sager: Identification of three related human GRO genes encoding cytokine functions. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Show all 6 references for ABIN2666642

  2. Human CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN2666640 : Carlson, Kroenke, Rao, Lane, Segal: The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. in The Journal of experimental medicine 2008 (PubMed)
    Show all 6 references for ABIN2666640

  3. Human CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN666759 : Jerva, Sullivan, Lolis: Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: sequence analysis and mutagenesis identify receptor binding epitopes. in Protein science : a publication of the Protein Society 1997 (PubMed)
    Show all 3 references for ABIN666759

  4. Mouse (Murine) CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN1046726 : Wolpe, Sherry, Juers, Davatelis, Yurt, Cerami: Identification and characterization of macrophage inflammatory protein 2. in Proceedings of the National Academy of Sciences of the United States of America 1989 (PubMed)

  5. Human CXCL2 Protein expressed in Wheat germ - ABIN1350823 : Nikolakopoulou, Dutta, Chen, Miller, Trapp: Activated microglia enhance neurogenesis via trypsinogen secretion. in Proceedings of the National Academy of Sciences of the United States of America 2013 (PubMed)

  6. Mouse (Murine) CXCL2 Protein expressed in Escherichia coli (E. coli) - ABIN2007271 : De Plaen, Han, Liu, Hsueh, Ghosh, May: Lipopolysaccharide induces CXCL2/macrophage inflammatory protein-2 gene expression in enterocytes via NF-kappaB activation: independence from endogenous TNF-alpha and platelet-activating factor. in Immunology 2006 (PubMed)

More Proteins for Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Interaction Partners

Horse (Equine) Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. Results suggested that chemokine (show CCL1 Proteins) expression by cultured equine BECs following exposure to pulmonary hemorrhage conditions may contribute to the development of inflammatory airway disease in horses.

  2. This study examined effects of in vitro exposure to solutions of hay (show GTF2H5 Proteins) dust, lipopolysaccharides, or beta-glucan on cytokine expression in pulmonary mononuclear cells isolated from healthy horses and horses with recurrent airway obstruction.

Human Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. Polymorphisms in the promoter regions of the CXCL1 and CXCL2 genes contribute to increased risk of alopecia areata in the Korean population

  2. The WDR26 (show WDR26 Proteins) gene was differentially methylated in monozygotic twins discordant for depressive disorder.

  3. In this review, a genetic variant in CXCL12 (show CXCL12 Proteins) is described that is associated with type 2 diabetes mellitus and its complications.

  4. We have demonstrated that GRObeta, as an oncogene (show RAB1A Proteins) product, contributed to tumorigenesis and metastasis of HCC (show FAM126A Proteins)

  5. Our results demonstrated that resistance to anti-proliferative effects of CXCR2 (show CXCR2 Proteins) may also arise from feedback increases in MIP-2 secretion.

  6. autophagy is required for Hepatitis B virus-induced NF-kappaB (show NFKB1 Proteins) activation and release of IL-6 (show IL6 Proteins), IL-8 (show IL8 Proteins), and CXCL2 in Hepatocytes

  7. The results link CXCL1 and CXCL2 chemokines with bone marrow adiposity and implicate CXCR2 (show CXCR2 Proteins) signaling in promoting effects of marrow fat on progression of skeletal tumors in bone.

  8. CXCL2 has antimicrobial activity against E. coli and S. aureus.

  9. Simultaneous targeting of hCAP-G2 and MIP-2A is a promising strategy for the development of antitumor drugs as a treatment for intractable tumours.

  10. our results demonstrate the diverse mechanisms by which CXCL2 and CXCL3 (show CXCL3 Proteins) mediate normal and asthmatic airway smooth muscle cell migration

Mouse (Murine) Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. p53 (show TP53 Proteins)-mediated induction of PAI-1 (show SERPINE1 Proteins) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1, CXCL2, and CXCR2 (show CXCR2 Proteins).

  2. Social defeat induced an exposure-dependent increase in mRNA levels of E-selectin (show SELE Proteins), CXCL1, and CXCL2 that increased with additional days of social defeat.

  3. MIP-2 directly impairs neonatal pulmonary endothelial cell migration in vitro.

  4. These results have suggested that the activation of MyD88 (show MYD88 Proteins) pathway by constitutive low-level IL-1beta (show IL1B Proteins) expression is essential for pressure force-induced CXCL2 and CCL2 (show CCL2 Proteins) expression in osteoblasts.

  5. SIRT2 (show SIRT2 Proteins) regulates LPS (show TLR4 Proteins) induced proximal renal tubules CXCL2 protein expression.

  6. miR26a/-26b-COX-2-MIP-2 loop regulates allergic inflammation and the feedback relationship between allergic inflammation and the enhanced tumorigenic and metastatic potential

  7. huH1N1 virus PA and NA mediated increased MIP-2 expression early postinfection, resulting in substantial pulmonary neutrophilia with enhanced lung pathology and disease

  8. Syndecan-1 (show SDC1 Proteins) is expressed in the parietal peritoneum microvasculature but does not regulate leukocyte recruitment and is not necessary for the presentation of the chemokine (show CCL1 Proteins) MIP-2 in this tissue.

  9. Identified TLR2 and S100A8 (show S100A8 Proteins)/S100A9 (show S100A9 Proteins) as key regulators of hepatic CXCL-2 expression and neutrophil recruitment.

  10. Suggest anti-inflammatory action of daidzein in lung epithelial cells is mediated via a direct interaction with PARP-1 (show PARP1 Proteins), which inhibits RelA/p65 (show NFkBP65 Proteins) protein PARylation required for the transcriptional modulation of pro-inflammatory chemokines such as Cxcl2.

Pig (Porcine) Chemokine (C-X-C Motif) Ligand 2 (CXCL2) interaction partners

  1. reports transmural and perivascular expression patterns of chemokines CCL2 (show CCL2 Proteins) and CXCL2 and of chemokine (show CCL1 Proteins) receptors CCR2 (show CCR2 Proteins), CCR5, and CXCR4 (show CXCR4 Proteins) following coronary angioplasty

CXCL2 Protein Profile

Protein Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene.

Gene names and symbols associated with CXCL2

  • chemokine (C-X-C motif) ligand 2 (CXCL2)
  • chemokine (C-X-C motif) ligand 2 (Cxcl2)
  • WD repeat domain 26 (WDR26)
  • CDW2 protein
  • CINC-2a protein
  • GID7 protein
  • Gro2 protein
  • GRO3 protein
  • GROB protein
  • GROX protein
  • Mgsa-b protein
  • MIP-2 protein
  • MIP-2a protein
  • MIP-2alpha protein
  • Mip2 protein
  • MIP2A protein
  • Scyb protein
  • SCYB2 protein

Protein level used designations for CXCL2

GRO-gamma , GRO3 oncogene , GRO3, growth related gene 3 , growth-regulated protein homolog gamma , C-X-C motif chemokine 2 , CINC-3 , MIP2 , cytokine-induced neutrophil chemoattractant 3 , macrophage inflammatory protein 2 , small inducible cytokine subfamily, member 2 , GRO2 oncogene , MGSA beta , MIP2-alpha , gro-beta , growth-regulated protein beta , macrophage inflammatory protein 2-alpha , melanoma growth stimulatory activity beta , chemokine ligand 2 , GRO-beta , GRO2, growth related gene 2 (GRO2 oncogene) , growth related oncogene X , growth-regulated protein homolog beta , CUL4- and DDB1-associated WDR protein 2 , GID complex subunit 7 homolog , WD repeat-containing protein 26 , myocardial ischemic preconditioning up-regulated protein 2 , myocardial ischemic preconditioning upregulated protein 2

GENE ID SPECIES
281214 Bos taurus
100233237 Equus caballus
114105 Rattus norvegicus
2920 Homo sapiens
20310 Mus musculus
414904 Sus scrofa
281734 Bos taurus
80232 Homo sapiens
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