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Chemokine (C-X-C Motif) Receptor 2 Proteins (CXCR2)

The protein encoded by CXCR2 is a member of the G-protein-coupled receptor family. Additionally we are shipping CXCR2 Antibodies (237) and CXCR2 Kits (35) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CXCR2 3579 P25025
CXCR2 12765 P35343
Rat CXCR2 CXCR2 29385 P35407
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Top CXCR2 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Wheat germ Human Un-conjugated   2 μg Log in to see 9 Days
$491.43
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   50 μg Log in to see 9 to 11 Days
$528.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   5 applications Log in to see 1 to 2 Days
$312.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CXCR2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine) ,

Top referenced CXCR2 Proteins

  1. Human CXCR2 Protein expressed in Wheat germ - ABIN1330037 : Spaan, Vrieling, Wallet, Badiou, Reyes-Robles, Ohneck, Benito, de Haas, Day, Jennings, Lina, Vandenesch, van Kessel, Torres, van Strijp, Henry: The staphylococcal toxins ?-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors. in Nature communications 2014 (PubMed)

More Proteins for Chemokine (C-X-C Motif) Receptor 2 (CXCR2) Interaction Partners

Human Chemokine (C-X-C Motif) Receptor 2 (CXCR2) interaction partners

  1. The results showed that the expression of N-Ac-PGP receptors (CXCR1 and CXCR2) in CESCs was upregulated by N-Ac-PGP.

  2. The results of this study show that the CXCR2 rs1126579 polymorphism is significantly associated with ischemic stroke, both individually and in combination with the genotype and/or alleles of other chemokine (show CCL1 Proteins) genes.

  3. These studies provide direct evidence linking the activation of IL8 (show IL8 Proteins), DNA demethylation and the induction of the OA process with important therapeutic implications therein for patients with this debilitating disease.

  4. Studied the expression of CXCL8 (show IL8 Proteins)-CXCR1 (show CXCR1 Proteins)/2 pathway, its impact on cell proliferation and cytokine expression in human colorectal carcinoma HCT116 cells.

  5. Inhibition of IL-8 (show IL8 Proteins) signalling can enhance response in platinum sensitive and resistant high grade serous ovarian carcinoma.

  6. CXCR2 expression is enriched in human atherosclerotic coronary artery.

  7. CXCR2-CXCL1 axis is correlated with neutrophil infiltration and predicts a poor prognosis in hepatocellular carcinoma

  8. we found the mRNA level of NF-kappaB (show NFKB1 Proteins) and IL-8 (show IL8 Proteins) was higher in gastric ulcer patients, especially in patients with H.pylori-positive gastric ulcer.

  9. Data show that trefoil factor-3 (TFF3 (show TFF3 Proteins)) secreted from mammary carcinoma cells promotes de novo angiogenesis via interleukin-8 (IL-8 (show IL8 Proteins))/IL-8 (show IL8 Proteins) receptor (show CXCR1 Proteins) CXCR2.

  10. G31P blockage of CXCR1 (show CXCR1 Proteins) and CXCR2 can inhibit human lung cancer cell growth and metastasis

Cow (Bovine) Chemokine (C-X-C Motif) Receptor 2 (CXCR2) interaction partners

  1. Results also demonstrated that in CXCR2 (show CXCR1 Proteins), genotypes BC, CC and FF were probably relevant with mastitis and the genotypes AA, AB and EE may have better milk quality.

Mouse (Murine) Chemokine (C-X-C Motif) Receptor 2 (CXCR2) interaction partners

  1. This study demonstated that endothelial CXCR2 play essential roles in cerebral endothelial activation and subsequent leukocyte recruitment during neuroinflammation.

  2. Studied DC-specific TLR4 (show TLR4 Proteins) signaling on host defense against intra-abdominal polymicrobial sepsis; found TLR4 (show TLR4 Proteins) deletion on DCs was associated with lower levels of IL-10 (show IL10 Proteins), higher PMN (show TBCE Proteins) accumulation in the peritoneal cavity, and higher expression of CXCR2.

  3. CXCL1 monomer-dimer distribution and receptor interactions are highly coupled and regulate neutrophil trafficking and that injury in the context of disease is a consequence of inappropriate CXCR2 activation

  4. p53 (show TP53 Proteins)-mediated induction of PAI-1 (show SERPINE1 Proteins) expression due to chronic CS exposure exacerbates lung inflammation through elaboration of CXCL1, CXCL2 (show CXCL2 Proteins), and CXCR2.

  5. Suggest chemotherapy-specific differential regulation of CXCR2 ligands, stem cell-like and mesenchymal phenotypes, and enhanced metastasis in drug-resistant cells and targeting CXCR2 signaling, may help circumvent therapy resistance in breast cancer.

  6. Serum amyloid A1alpha induces paracrine IL-8/CXCL8 (show IL8 Proteins) via TLR2 and directly synergizes with this chemokine (show CCL1 Proteins) via CXCR2 and formyl peptide receptor 2 (show FPR2 Proteins) to recruit neutrophils.

  7. Blockade of CXCR2 during Hpb challenge infection reproduced the delayed wound repair observed in helminth infected Aid-/- and Fcrg (show FCER1G Proteins)-/- mice.

  8. CXCR2 and CX3CR1 (show CX3CR1 Proteins) differentially regulate EPC (show TCF21 Proteins) functional responses during atheroregression

  9. CXCr2 regulates the hepatic proliferative response and subsequent liver regeneration.

  10. Data revealed a critical role of a PDZ-based CXCR2 macromolecular complex in EPC (show TCF21 Proteins) homing and angiogenesis.

CXCR2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with CXCR2

  • chemokine (C-X-C motif) receptor 2 (Cxcr2)
  • chemokine (C-X-C motif) receptor 2 (CXCR2)
  • chemokine (C-X-C motif) receptor 2 (IL8RB)
  • interleukin 8 receptor, beta (CXCR2)
  • CD128 protein
  • CD182 protein
  • CDw128 protein
  • CDw128b protein
  • Cmkar2 protein
  • CXC-R2 protein
  • CXCR-2 protein
  • Gpcr16 protein
  • IL-8rb protein
  • IL-8Rh protein
  • IL8R2 protein
  • IL8RA protein
  • Il8rb protein
  • mIL-8RH protein

Protein level used designations for CXCR2

C-X-C chemokine receptor type 2 , interleukin 8 receptor beta , interleukin-8 receptor CXCR2 , CXC-R2 , CXCR-2 , CXCR2 gene for IL8 receptor type B , GRO/MGSA receptor , IL-8 receptor type 2 , IL-8R B , chemokine (CXC) receptor 2 , high affinity interleukin-8 receptor B , interleukin 8 receptor B , interleukin 8 receptor type 2 , interleukin 8 receptor, beta , interleukin-8 receptor type B , chemokine receptor CXCR2 , interleukin 8 receptor, alpha , IL-8 receptor alpha chain , chemokine (C-X-C) receptor 2 , IL-8 receptor , High affinity interleukin-8 receptor B , interleukin-8 receptor, beta

GENE ID SPECIES
100379569 Cavia porcellus
3579 Homo sapiens
782719 Bos taurus
12765 Mus musculus
100328627 Oryctolagus cuniculus
29385 Rattus norvegicus
700407 Macaca mulatta
470644 Pan troglodytes
478905 Canis lupus familiaris
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