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CXCR7 encodes a member of the G-protein coupled receptor family. Additionally we are shipping CXCR7 Kits (11) and and many more products for this protein.
Showing 10 out of 136 products:
Human Monoclonal CXCR7 Primary Antibody for FACS - ABIN2661157
Burns, Summers, Wang, Melikian, Berahovich, Miao, Penfold, Sunshine, Littman, Kuo, Wei, McMaster, Wright, Howard, Schall: A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. in The Journal of experimental medicine 2006
Show all 4 references for ABIN2661157
Human Polyclonal CXCR7 Primary Antibody for EIA, IHC (fro) - ABIN492896
Tran, Miller: Chemokine receptors: signposts to brain development and disease. in Nature reviews. Neuroscience 2003
Show all 4 references for ABIN492896
Human Polyclonal CXCR7 Primary Antibody for EIA, IHC (p) - ABIN951737
Berahovich, Zabel, Penfold, Lewén, Wang, Miao, Gan, Pereda, Dias, Slukvin, McGrath, Jaen, Schall: CXCR7 protein is not expressed on human or mouse leukocytes. in Journal of immunology (Baltimore, Md. : 1950) 2010
Show all 3 references for ABIN951737
Human Polyclonal CXCR7 Primary Antibody for EIA, IHC (p) - ABIN453592
Sreedharan, Robichon, Peterson, Goetzl: Cloning and expression of the human vasoactive intestinal peptide receptor. in Proceedings of the National Academy of Sciences of the United States of America 1991
Human Polyclonal CXCR7 Primary Antibody for IF, ELISA - ABIN1535576
Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005
The scattershot allele results in an in-frame deletion of 8 amino acids at the junction of the third transmembrane domain and the second intracellular loop of Tre1 that dramatically impairs the function of this GPCR in germ cell migration.
plays an important role in regulation of germ cell migration, polarity , cell adhesion, and cadherin binding. (review)
Tre1 is a G protein-coupled receptor (show GPBAR1 Antibodies) that directs transepithelial migration of Drosophila germ cells
Down-regulation of E-cadherin causes germ cell dispersal but is not sufficient for transepithelial migration in the absence of Tre1, suggesting a new mechanism for Tre1 GPCR function that links cell polarity, modulation of cell adhesion, and invasion.
CXCL12 (show CXCL12 Antibodies) may be an effective diagnostic marker for papillary thyroid carcinoma, and CXCL12 (show CXCL12 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCR7 axis may contribute to thyroid cancer development by regulating cancer cell migration and invasion via AKT (show AKT1 Antibodies) and ERK (show EPHB2 Antibodies) signaling and MMP-2 (show MMP2 Antibodies) activation.
Our study suggested that CXCR7 plays an important proangiogenic role in hepatocellular carcinoma (HCC (show FAM126A Antibodies)). via activation of the AKT (show AKT1 Antibodies) pathway. So CXCR7 may be a potential target for antiangiogenic therapy in HCC (show FAM126A Antibodies)
CXCR7 is a direct downstream target of miR (show MLXIP Antibodies)-100, and overexpression of miR (show MLXIP Antibodies)-100 efficiently suppresses CXCR7 expression.
Overexpression of CXCR7 is associated with breast cancer.
High CXCR7 expression is associated with endometrial cancer.
the current study revealed that CXCL12 (show CXCL12 Antibodies) which combined its receptors CXCR4 (show CXCR4 Antibodies) and CXCR7 together could promote cell migration and cell invasion of OSCC.
Increased CXCR7 expression is associated with invasion in nasopharyngeal carcinoma.
Up-regulation of miR (show MLXIP Antibodies)-218 expression in renal cell carcinoma (show MOK Antibodies) under hypoxia can result in significant and targeted down-regulation of CXCR7 expression.
CXCR7 affects the growth of PTC (show F9 Antibodies) cells.
CXCR7 may play a role in the progression, metastasis and angiogenesis of otorhinolaryngologic tumours.
expression of CXCR7 in normal and pathological nervous system suggests CXCR4 (show CXCR4 Antibodies)-independent functions of SDF-1/CXCL12 (show CXCL12 Antibodies) mediated through its interaction with CXCR7
confirm a pivotal role of the SDF-1 (show CXCL12 Antibodies)/CXCR4 (show CXCR4 Antibodies)/CXCR7 axis for chronic allograft vasculopathy development
our present study provided evidence that SDF-1 (show CXCL12 Antibodies) mediated CSCs migration through CXCR4 (show CXCR4 Antibodies) and CXCR7 via MEK (show MDK Antibodies)/ERK (show EPHB2 Antibodies) and PI3K/Akt (show AKT1 Antibodies) pathway
Endothelial CXCR7 limits breast cancer metastasis at multiple steps in the metastatic cascade, advancing understanding of CXCL12 (show CXCL12 Antibodies) pathways in tumor environments and informing ongoing drug development targeting CXCR7 in cancer.
Sata demonstrate that CXCR7 has a role in the positioning of hem and pallium-subpallium boundary-derived Cajal-Retzius (CR)cells, CXCL12 (show CXCL12 Antibodies) regulating CR cell subpial localization through the combined action of CXCR4 (show CXCR4 Antibodies) and CXCR7.
CXCR7 acts to prevent epithelial damage and ameliorate fibrosis after a single lung injury, repeated injury leads to suppression of CXCR7 expression and recruitment of VEGFR1 (show FLT1 Antibodies) expressing macrophages, Wnt (show WNT2 Antibodies) and Notch (show NOTCH1 Antibodies) signaling, and enhanced fibrosis.
CXCR7 overexpression in MSCs reversed the inhibitory effect of high concentrations of SDF-1alpha.
Collectively, our data demonstrate that CXCR7 suppression modulates microglial chemotaxis to ameliorate EAE.
Both CXCR7 and Rac1 are required for extracellular signal-regulated kinases (ERK) 1 (show MAPK3 Antibodies)/2 activation and subsequent NPC (show NPC1 Antibodies) migration, indicating that CXCR7 could serve as a functional receptor in CXCL12 (show CXCL12 Antibodies)-mediated NPC (show NPC1 Antibodies) migration independent of CXCR4 (show CXCR4 Antibodies).
Blockade of CXCR7 suppressed MIF (show MIF Antibodies)-mediated ERK (show EPHB2 Antibodies)- and zeta-chain-associated protein kinase (show CDK7 Antibodies) (ZAP)-70 (show ZAP70 Antibodies) activation
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
, G protein coupled receptor
, trapped in endoderm 1
, trapped in endoderm-1
, C-X-C chemokine receptor type 7
, G protein-coupled receptor
, G-protein coupled receptor 159
, G-protein coupled receptor RDC1 homolog
, chemokine (C-X-C motif) receptor 7
, chemokine orphan receptor 1
, RDC1-like G protein-coupled receptor
, G-protein coupled receptor RDC1