CXCR7 antibody

Catalog No. ABIN7249546

The Rabbit Polyclonal anti-CXCR7 antibody is suitable to detect CXCR7 in samples from Human, Mouse and Rat. It has been validated for IHC.

Quick Overview for CXCR7 antibody (ABIN7249546)

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR7 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Product Details anti-CXCR7 Antibody

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: KLH conjugated Synthetic peptide corresponding to Mouse CXCR7

Isotype: IgG

Application Details

Application Notes: IHC 1:100-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 130 μg/mL

Buffer: PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for CXCR7

Target: CXCR7 (Chemokine (C-X-C Motif) Receptor 7 (CXCR7))

Alternative Name: CXCR7

Background: CXCR7 (C-X-C chemokine receptor type 7),also known as RDC1,is a member of the G-protein coupled receptor family. CXCR7 can bind the chemokines CXCL11 and CXCL12 with high affinity,and it also acts as coreceptor with CXCR4 for a restricted number of HIV isolates. Expression of CXCR7 has been associated with cardiac development as well as with tumor growth and progression.

UniProt: P25106, P56485, O89039

Pathways: Myometrial Relaxation and Contraction, Negative Regulation of intrinsic apoptotic Signaling