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anti-Chemokine Binding Protein 2 (CCBP2) Antibodies

CCBP2 encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Additionally we are shipping CCBP2 Kits (4) and CCBP2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CCBP2 1238 O00590
CCBP2 59289 O08707
CCBP2 140473  
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Top anti-CCBP2 Antibodies at antibodies-online.com

Showing 10 out of 82 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-CCBP2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-CCBP2 Pab (ABIN388746) in mouse small intestine tissue lysate. CCBP2 (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-CCBP2 N-term Pab (ABIN388745) is used in Western blot to detect CCBP2 in mouse liver tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from HepG2 cells, using CCBP2 Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of COS7 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of A549 cells, using CCBP2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p) Brain, Purkinje neurons 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC (p) Immunohistochemical staining of Placenta using anti- CCBP2 antibody ABIN122095 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

CCBP2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine) ,
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Rat (Rattus)


Top referenced anti-CCBP2 Antibodies

  1. Human Polyclonal CCBP2 Primary Antibody for EIA, IHC (p) - ABIN357386 : Kunkel, Kim, Lazarus, Vierra, Soler, Bowman, Butcher: CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells. in The Journal of clinical investigation 2003 (PubMed)
    Show all 5 references for ABIN357386

  2. Human Polyclonal CCBP2 Primary Antibody for IHC (p), WB - ABIN388746 : Fra, Locati, Otero, Sironi, Signorelli, Massardi, Gobbi, Vecchi, Sozzani, Mantovani: Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 3 references for ABIN388746

  3. Human Polyclonal CCBP2 Primary Antibody for IHC (p), WB - ABIN388745 : Soler, Humphreys, Spinola, Campbell: CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking. in Blood 2003 (PubMed)
    Show all 3 references for ABIN388745

  4. Human Polyclonal CCBP2 Primary Antibody for IHC, WB - ABIN2779383 : Galliera, Jala, Trent, Bonecchi, Signorelli, Lefkowitz, Mantovani, Locati, Haribabu: beta-Arrestin-dependent constitutive internalization of the human chemokine decoy receptor D6. in The Journal of biological chemistry 2004 (PubMed)

More Antibodies against CCBP2 Interaction Partners

Human Chemokine Binding Protein 2 (CCBP2) interaction partners

  1. Data show the structural motifs in the atypical chemokine receptor (show CCR1 Antibodies) 2 (ACKR2) are responsible for ligand binding, and suggest ACKR2-derived N-terminal peptides as being of potential therapeutic significance.

  2. engagement of the ACR (show ACR Antibodies) D6 by its ligands activates a beta (show SUCLA2 Antibodies)-arrestin1 (show ARRB1 Antibodies)-dependent, G protein-independent signaling pathway that results in the phosphorylation of the actin-binding protein (show KPTN Antibodies) cofilin (show CFL1 Antibodies) through the Rac1-PAK1 (show PAK1 Antibodies)-LIMK1 (show LIMK1 Antibodies) cascade.

  3. co-expression of DARC (show DARC Antibodies), D6, and CCX-CKR (show CCRL1 Antibodies) significantly associated with higher survival in gastric cancer

  4. CCL2 binding to primary adult human astrocytes is CCR2-independent and is likely to be mediated via the D6 decoy.

  5. D6 is expressed in AMs (show MAT1A Antibodies) from patients with COPD (show ARCN1 Antibodies), and its expression correlates with the degree of functional impairment and markers of immune activation.

  6. Chemokine (show CCL1 Antibodies) decoy receptor D6 limits CC-chemokine (show CCL1 Antibodies)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.

  7. DARC (show DARC Antibodies) and D6, the most studied members of this group of molecules, are reviewed.

  8. CCR10 (show CCR10 Antibodies) is unlikely to be necessary for cutaneous homing of TH cells in the models studied here. CCR10 (show CCR10 Antibodies) may instead play a role in the movement of specialized "effector" cutaneous TH cells to and/or within epidermal microenvironments.

  9. CCR10 and its mucosal epithelial ligand CCL28 have roles in the migration of circulating IgA plasmablasts

  10. D6 is constitutively internalized via a ligand-independent, phosphorylation-independent association with beta-arrestin.

Mouse (Murine) Chemokine Binding Protein 2 (CCBP2) interaction partners

  1. ACKR4 on stromal cells aids the egress of antigen presenting cells from mouse skin, and, during inflammation, facilitates CCR7 (show CCR7 Antibodies)-dependent cell trafficking by scavenging CCL19 (show CCL19 Antibodies).

  2. The data shows a novel function for the chemokine receptor (show CCR1 Antibodies) CCX-CKR (show CCRL1 Antibodies) as a regulator of TGF-beta1 (show TGFB1 Antibodies) expression and epithelial-mesenchymal transition in breast cancer cells.

  3. CCRL1 (show CCRL1 Antibodies) is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice.

  4. Further examination revealed that proximity of pro-lymphangiogenic macrophages to developing lymphatic vessel surfaces is increased in ACKR2-deficient mice and reduced in CCR2-deficient mice.

  5. stepwise acquisition of chemokine (C-C motif) receptor-like 1 (CCRL1 (show CCRL1 Antibodies)) is a late determinant of cortical thymic epithelial cell differentiation

  6. some cells, including plasmacytoid dendritic cells, can express both CCR2 (show CCR2 Antibodies) and ACKR2; that Ly6C(high) monocytes have particularly strong CCL2 (show CCL2 Antibodies)-scavenging potential in vitro and in vivo; and that CCR2 (show CCR2 Antibodies) is a much more effective CCL2 (show CCL2 Antibodies) scavenger than ACKR2.

  7. found that lymph node fringes indeed contained physiological gradients of the chemokine (show CCL1 Antibodies) CCL21 (show CCL21 Antibodies), which depended on the expression of CCRL1 (show CCRL1 Antibodies), the atypical receptor for the CCR7 (show CCR7 Antibodies) ligands CCL19 (show CCL19 Antibodies) and CCL21 (show CCL21 Antibodies)

  8. CCX-CKR (show CCRL1 Antibodies) deletion increases incidence of a spontaneous Sjogren's syndrome-like pathology, suggestive of a defect in self-tolerance. CCX-CKR (show CCRL1 Antibodies)(-/-) mice have fewer thymic epithelial cells per thymocyte, with defects in thymocyte distribution & frequency.

  9. Chemokine (show CCL1 Antibodies) decoy receptor D6 limits CC-chemokine (show CCL1 Antibodies)-dependent pathogenic inflammation and is required for adequate cardiac remodeling after myocardial infarction.

  10. control of CCR2 ligands by D6 regulates the traffic of Ly6C(high) monocytes and controls their immunosuppressive potential.

CCBP2 Antigen Profile

Protein Summary

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members\; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Gene names and symbols associated with CCBP2

  • chemokine binding protein 2 (CCBP2) antibody
  • atypical chemokine receptor 2 (ACKR2) antibody
  • chemokine binding protein 2 (LOC100219492) antibody
  • chemokine binding protein 2 (LOC100230349) antibody
  • chemokine binding protein 2 (LOC100345678) antibody
  • chemokine receptor D6 (LOC733624) antibody
  • atypical chemokine receptor 2 (Ackr2) antibody
  • atypical chemokine receptor 4 (Ackr4) antibody
  • A630091E18Rik antibody
  • AI464239 antibody
  • Ccbp2 antibody
  • CCR9 antibody
  • CCR10 antibody
  • CCR11 antibody
  • Ccrl1 antibody
  • CCX-CKR antibody
  • CCX-CKR1 antibody
  • Cmkbr9 antibody
  • Cmkbrl1 antibody
  • D6 antibody
  • hD6 antibody
  • LOC733624 antibody
  • PPR1 antibody
  • VSHK1 antibody

Protein level used designations for CCBP2

chemokine binding protein 2 , chemokine-binding protein 2 , chemokine receptor D6 , C-C chemokine receptor D6 , CC-chemokine-binding receptor JAB61 , chemokine (C-C motif) receptor 9 , chemokine (C-C) receptor 9 , chemokine receptor CCR-10 , chemokine receptor CCR-9 , chemokine-binding protein D6 , D6 beta-chemokine receptor , CCR10-related receptor , C-C CKR-11 , C-C chemokine receptor type 11 , CC chemokine receptor-like 1 , CC-CKR-11 , CCR-11 , CCX CKR , chemokine (C-C motif) receptor-like 1 , chemokine (C-C) receptor-like 1 , chemokine receptor CCR11

GENE ID SPECIES
420393 Gallus gallus
460298 Pan troglodytes
485618 Canis lupus familiaris
512583 Bos taurus
100219492 Taeniopygia guttata
100230349 Taeniopygia guttata
100345678 Oryctolagus cuniculus
733624 Sus scrofa
100589553 Nomascus leucogenys
1238 Homo sapiens
59289 Mus musculus
140473 Rattus norvegicus
252837 Mus musculus
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