CCBP2 antibody (AA 138-384)

Catalog No. ABIN6719286

Product Details anti-CCBP2 Antibody

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Binding Specificity: AA 138-384

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for D6/ACKR2 detection. Tested with WB, IHC-P, Direct ELISA in Human.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for D6/ACKR2 detection. Tested with WB, IHC-P, Direct ELISA in Human.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human D6/ACKR2 recombinant protein (Position: M138-A384).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for CCBP2

Target: CCBP2 (Chemokine Binding Protein 2 (CCBP2))

Alternative Name: ACKR2 (CCBP2 Products)

Synonyms: CCBP2 antibody, CCR10 antibody, CCR9 antibody, CMKBR9 antibody, D6 antibody, hD6 antibody, Ccbp2 antibody, LOC733624 antibody, A130091K22Rik antibody, Cmkbr10 antibody, GPR-9-6 antibody, AI464239 antibody, Cmkbr9 antibody, atypical chemokine receptor 2 antibody, atypical chemokine receptor 2-like antibody, chemokine receptor D6 antibody, chemokine (C-C motif) receptor 9 antibody, C-C motif chemokine receptor 9 antibody, ACKR2 antibody, Ackr2 antibody, LOC100219492 antibody, LOC733624 antibody, Ccr9 antibody, CCR9 antibody

Background:

Synonyms: Atypical chemokine receptor 2, C-C chemokine receptor D6, Chemokine receptor CCR-10, Chemokine receptor CCR-9, Chemokine-binding protein 2, Chemokine-binding protein D6, ACKR2, CCBP2, CCR10, CMKBR9, D6

Background: This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members, however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Gene ID: 1238

UniProt: O00590