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Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) Proteins (CHRNA5)

The protein encoded by CHRNA5 is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. Additionally we are shipping CHRNA5 Antibodies (64) and CHRNA5 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CHRNA5 1138 P30532
Rat CHRNA5 CHRNA5 25102  
CHRNA5 110835 Q2MKA5
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Top CHRNA5 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Cells Human His tag   100 μg Log in to see 16 Days
$437.80
Details

CHRNA5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine)

More Proteins for Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5) Interaction Partners

Human Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5) interaction partners

  1. Preventive interventions in adolescents reduced the genetic risk for smoking from rs16969968 CHRNA5.

  2. suggest that gene variance in the CHRNA5-CHRNA3 (show CHRNA3 Proteins)-CHRNB4 cluster is associated with an increased risk of death, incidence of COPD (show ARCN1 Proteins) and tobacco-related cancer in smokers

  3. two SNPs (rs6495308 and rs11072768) in CHRNA5-A3-B4 have a indirect effect on lung cancer through smoking behaviors

  4. These results suggest that exposure to nicotine might negatively impact the apoptotic potential of chemotherapeutic drugs and that alpha5-nAChR (show CHRNA4 Proteins)/AKT (show AKT1 Proteins) signaling plays a key role in the anti-apoptotic activity of nicotine induced by cisplatin.

  5. A novel regulatory SNP association with nicotine dependence was found. Previously observed differences in CHRNA5 mRNA expression and nicotine dependence risk were connected to underlying DNA methylation (show HELLS Proteins) differences.

  6. This study showed that CHRNA5(rs16969968) interacted with chronic low family support in association with child mental health status

  7. Data suggest that CHRNA5-A3-B4 gene variants do not exhibit a robust association with smoking cessation and are unlikely to be useful for clinically optimizing smoking cessation pharmacotherapy for Caucasian smokers.

  8. In non-Hispanic White participants, a novel association between rs1289899 in the CHRNA5 gene and posttraumatic stress disorder was observed.

  9. Four SNPs in the CHRNA3/5 locus are associated with chronic obstructive pulmonary disease risk. [Meta-analysis]

  10. CHRNA5-A3-B4 genotype associates with body mass index in never smokers.

Mouse (Murine) Cholinergic Receptor, Nicotinic, alpha 5 (Neuronal) (CHRNA5) interaction partners

  1. These results highlight the involvement of the alpha5 nAChR (show CHRNA4 Proteins) subunit in the development of hyperalgesia, allodynia and inflammation associated with chronic neuropathic and inflammatory pain models.

  2. Overexpression of the genomic cluster CHRNA5/A3/B4 in mice increases somatic signs associated with morphine withdrawal and Knockout of alpha5 gene reduced somatic signs in morphine-treated mice

  3. Data reveal a highly regulated temporal-spatial pattern of alpha5 nAChR (show CHRNA4 Proteins) subunit expression during important periods of lung morphogenesis by FoxA2 (show FOXA2 Proteins).

  4. increased nicotine intake in mice with a null mutation in Chrna5

  5. Polymorphisms located within the Chrna5-Chrna3-Chrnb4 cluster on mouse chromosome 9 were found to co-segregate with alcohol preference, with high-drinking F(2) mice carrying B6 alleles and low-drinking F(2) mice carrying D2 alleles.

CHRNA5 Protein Profile

Protein Summary

The protein encoded by this gene is a nicotinic acetylcholine receptor subunit and a member of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. These receptors are thought to be heteropentamers composed of separate but similar subunits. Defects in this gene have been linked to susceptibility to lung cancer type 2 (LNCR2).

Gene names and symbols associated with CHRNA5

  • cholinergic receptor, nicotinic, alpha 5 (chrna5)
  • cholinergic receptor, nicotinic, alpha 5 (CHRNA5)
  • cholinergic receptor, nicotinic, alpha 5 (neuronal) (CHRNA5)
  • cholinergic receptor, nicotinic, alpha 5 (neuronal) (chrna5)
  • cholinergic receptor, nicotinic, alpha 5 (neuronal) (Chrna5)
  • cholinergic receptor, nicotinic, alpha polypeptide 5 (Chrna5)
  • Acra-5 protein
  • Acra5 protein
  • LNCR2 protein
  • zgc:110642 protein

Protein level used designations for CHRNA5

neuronal acetylcholine receptor subunit alpha-5 , cholinergic receptor, nicotinic, alpha polypeptide 5 , Cholinergic receptor, neuronal nicotinic, alpha polypeptide-5 , acetylcholine receptor, nicotinic, alpha 5 (neuronal) , neuronal nicotinic acetylcholine receptor, alpha5 subunit , acetylcholine receptor alpha 5 , cholinergic receptor neuronal nicotinic alpha protein 5 , nicotinic acetylcholine receptor alpha5 subunit

GENE ID SPECIES
550584 Danio rerio
282177 Bos taurus
1138 Homo sapiens
446384 Xenopus laevis
386577 Gallus gallus
482112 Canis lupus familiaris
25102 Rattus norvegicus
619369 Pan troglodytes
110835 Mus musculus
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