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Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Additionally we are shipping CBX6 Antibodies (58) and CBX6 Kits (1) and many more products for this protein.
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different CBX (show CBX1 Proteins) proteins are recruited to distinct chromatin regions through nonconserved interactions. Metaphase spreads revealed reciprocal patterns of chromosome association by CBX2 (show CBX2 Proteins) and CBX6
our results represent the first evidence that CBX6 contributes to tumor progression and indicate that the protein may serve as a novel prognostic biomarker for hepatocellular carcinoma and as a therapeutic target in the treatment of the disease.
Data show that polycomb (show CBX2 Proteins)-group proteins BMI1 (show BMI1 Proteins), PHC3 (show PHC3 Proteins), CBX6 and CBX7 (show CBX7 Proteins) expression was significantly increased during imatinib treatment.
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
chromobox homolog 6
, chromobox protein homolog 6
, chromobox-like protein 6
, chromobox 6