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Chromosome 2 Open Reading Frame 40 Proteins (C2orf40)

Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.. Additionally we are shipping Chromosome 2 Open Reading Frame 40 Antibodies (61) and Chromosome 2 Open Reading Frame 40 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
C2orf40 84417 Q9H1Z8
Mouse C2orf40 C2orf40 78896 Q99LS0
C2orf40 363225 D4A540
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Top Chromosome 2 Open Reading Frame 40 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Quantity Supplier Delivery Price Details
Yeast Cow His tag 1 mg Log in to see 56 to 66 Days
$2,053.33
Details
Yeast Rat His tag 1 mg Log in to see 56 to 66 Days
$2,057.00
Details
Yeast Xenopus tropicalis His tag 1 mg Log in to see 56 to 66 Days
$2,057.00
Details
Yeast Xenopus laevis His tag 1 mg Log in to see 56 to 66 Days
$2,057.00
Details
HOST_Human Human Un-conjugated 20 μg Log in to see 9 to 11 Days
$785.40
Details

C2orf40 Proteins by Origin and Source

Origin Expressed in Conjugate
Human
Rat (Rattus)

More Proteins for Chromosome 2 Open Reading Frame 40 (C2orf40) Interaction Partners

Human Chromosome 2 Open Reading Frame 40 (C2orf40) interaction partners

  1. low expression or no expression of ECRG4 in esophageal cancer tissues was closely related to the degree of tumor invasion level, TNM (show ODZ1 Proteins) staging, lymph node metastasis and recurrence and survival after surgery.

  2. loss of ECRG4 protein expression may be involved in tumor progression and may serve as a prognostic biomarker for breast cancer.

  3. Overexpression of ECRG4 inhibited laryngeal cancer cell proliferation and induced cancer cell apoptosis.

  4. Our data suggest that methylation-mediated suppression of the ECRG4 gene occurs frequently in nasopharyngeal carcinoma

  5. Results identify Ecrg4 as a paracrine factor that activates microglia and is chemotactic for monocytes, with potential as an antitumor therapeutic.

  6. ECRG4 is present on the surface of human monocytes and granulocytes and its interaction with the innate immunity receptor complex supports a role for cell surface activation of ECRG4 during inflammation

  7. The expression of ECRG4 is frequently upregulated in a papillary thyroid carcinoma through the demethylation mechanism of CpG islands in the gene promoter region, and the ECRG4 has a tumor-promoting function through inducing the cell cycle transition

  8. ECRG4 is a candidate tumor suppressor gene that might be involved in the proliferation of esophageal squamous cell carcinoma

  9. results suggest that C2ORF40 acts as a tumor suppressor gene in breast cancer pathogenesis and progression and is a candidate prognostic marker for this disease

  10. overexpression of ECRG4 enhanced the chemosensitivity of gastric cancer SGC (show SGCB Proteins)-7901 cells to 5-FU through induction of apoptosis.

Mouse (Murine) Chromosome 2 Open Reading Frame 40 (C2orf40) interaction partners

  1. proteolytic cleavage by furin (show FURIN Proteins) is a posttranslational requirement for proaugurin to suppress cell proliferation

  2. identified esophageal cancer-related gene 4 (Ecrg4) as a senescence inducer with implications for the senescence-like state of postmitotic cells in the aging brain.

  3. ECRG4 level in differentiated chondrocytes is decreased during hypertrophic maturation

Chromosome 2 Open Reading Frame 40 (C2orf40) Protein Profile

Protein Summary

Probable hormone that may induce senescence of oligodendrocyte and neural precursor cells, characterized by G1 arrest, RB1 dephosphorylation and accelerated CCND1 and CCND3 proteasomal degradation.

Gene names and symbols associated with C2orf40

  • esophageal cancer related gene 4 protein (LOC100345571)
  • chromosome 2 open reading frame 40 (C2orf40)
  • chromosome 11 open reading frame, human C2orf40 (C11H2orf40)
  • chromosome 2 open reading frame 40 (c2orf40)
  • RIKEN cDNA 1500015O10 gene (1500015O10Rik)
  • similar to RIKEN cDNA 1500015O10 (RGD1305645)
  • Ecrg4 protein
  • ecrg4-A protein

Protein level used designations for C2orf40

esophageal cancer related gene 4 protein , augurin , esophageal cancer-related gene 4 protein , UPF0689 protein C2orf40 homolog , esophageal cancer-related gene 4 protein homolog

GENE ID SPECIES
100345571 Oryctolagus cuniculus
713611 Macaca mulatta
515133 Bos taurus
84417 Homo sapiens
373779 Xenopus laevis
78896 Mus musculus
363225 Rattus norvegicus
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