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Chromosome 4 Open Reading Frame 7 Proteins (C4orf7)

C4orf7 encodes a small secreted protein that is expressed in follicular dendritic cells. Additionally we are shipping Chromosome 4 Open Reading Frame 7 Antibodies (20) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse C4orf7 C4orf7 494497  
C4orf7 260436 Q8NFU4
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Top Chromosome 4 Open Reading Frame 7 Proteins at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details

C4orf7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Top referenced Chromosome 4 Open Reading Frame 7 Proteins

  1. Human C4orf7 Protein expressed in Escherichia coli (E. coli) - ABIN1098501 : Al-Alwan, Du, Hou, Nashed, Fan, Yang, Marshall: Follicular dendritic cell secreted protein (FDC-SP) regulates germinal center and antibody responses. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 references for ABIN1098501

More Proteins for Chromosome 4 Open Reading Frame 7 (C4orf7) Interaction Partners

Mouse (Murine) Chromosome 4 Open Reading Frame 7 (C4orf7) interaction partners

  1. Our results demonstrate a novel biological activity of FDC-SP in controlling B-cell IgA production and identify FDC-SP-deficient mice as a novel mouse model of IgAN.

Human Chromosome 4 Open Reading Frame 7 (C4orf7) interaction partners

  1. FDC-SP may be involved in IgA production in the tonsils of Immunoglobulin A nephropathy patients.

  2. FDC-SP overexpression inhibits osteogenic differentiation of hPDLCs. study contributes to a better understanding of biological functions governing FDC-SP-induced hPDLC differentiation.

  3. Our findings demonstrate that transfection with FDC-SP has negligible adverse effect on proliferation of hPDLCs and imply the biological function of FDC-SP as a fibroblastic phenotype stabilizer

  4. The role of C4orf7 in ovarian cancer cell morphology, motility and invasion was demonstrated.

  5. FDC-SP has a very restricted tissue distribution, expressed by activated FDCs from tonsils and TNF-alpha (show TNF Proteins)-activated FDC (show LAG3 Proteins)-like cell lines, but not by B cell lines, primary germinal center B cells, or anti-CD40 (show CD40 Proteins) plus IL-4 (show IL4 Proteins)-activated B cells.

  6. Since only normal tissue was examined, these findings suggest that FDC-SP plays an important but previously unsuspected role within oral connective tissue.

  7. These results provide the first evidence for immunomodulatory activities of FDC-SP and implicate this molecule as a regulator of B cell responses.

Chromosome 4 Open Reading Frame 7 (C4orf7) Protein Profile

Protein Summary

This gene encodes a small secreted protein that is expressed in follicular dendritic cells. This protein specifically binds to activated B cells, and functions as a regulator of antibody responses. It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion.

Gene names and symbols associated with C4orf7

  • cDNA sequence BC037156 (BC037156)
  • chromosome 4 open reading frame 7 (LOC742341)
  • follicular dendritic cell secreted protein (FDCSP)
  • C4orf7 protein
  • FDC-SP protein

Protein level used designations for C4orf7

follicular dendritic cell secreted peptide , chromosome 4 open reading frame 7 , FDC secreted protein

GENE ID SPECIES
494497 Mus musculus
742341 Pan troglodytes
260436 Homo sapiens
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