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anti-Chromosome 9 Open Reading Frame 72 (C9ORF72) Antibodies

Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from C9ORF72 is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Additionally we are shipping C9ORF72 Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
C9ORF72 203228 Q96LT7
C9ORF72    
C9ORF72    
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Top anti-C9ORF72 Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB C9orf46 Antibody (C-term) western blot analysis in 293 cell line lysates (35µg/lane).This demonstrates the C9orf46 antibody detected the C9orf46 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB C9orf72 Antibody (C-term) (ABIN656852) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the C9orf72 antibody detected the C9orf72 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: C9orf72 Antibody [NBP1-93504] - Staining of human colon shows strong cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: C9orf72 Antibody [NBP1-93504] - Staining of human cell line U-2 OS shows positivity in cytoplasm & actin filaments. Antibody staining is shown in green. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Formalin-fixed and paraffin embedded rat brain with labeled Anti-C9orf72 Polyclonal Antibody, Unconjugated (ABIN1386141) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: C9orf72 Antibody [NBP2-15656] - Analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution. Western Blot: C9orf72 Antibody [NBP2-15656] - Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: C9orf72 transfected 293T lysate 10% SDS PAGE gel, diluted at 1:5000. 0.1 mL Log in to see 6 to 9 Days
$447.56
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ICC, IF, WB Western Blot: C9orf72 Antibody [NBP2-47146] - Western Blot Image of anti-C9orf72. Whole cell protein from SK-N-SH (lane 1) and SH-SY-5Y (lane 2) was separated on a 4-15% gel by SDS-PAGE, transferred to PVDF membrane and blocked in 5% non-fat milk in TBST. The membrane was probed with 2.0 ug/ml anti-hnRNP in 1% milk, and detected with an anti-rabbit HRP secondary antibody using chemiluminescence. Immunocytochemistry/Immunofluorescence: C9orf72 Antibody [NBP2-47146] - HeLa cells were fixed for 10 minutes using 10% formalin and then permeabilized for 5 minutes using 1X TBS + 0.5% Triton-X100. The cells were incubated with anti-C9orf72 (NBP2-47146) at a 1:100 dilution overnight at 4C and detected with an anti-rabbit Dylight 488 (Green) at a 1:500 dilution. Alpha tubulin (DM1A) ABIN4286691 was used as a co-stain at a 1:1000 dilution and detected with an anti-mouse Dylight 550 (Red) at a 1:500 dilution. Nuclei were counterstained with DAPI (Blue). Cells were imaged using a 40X objective. 0.1 mL Log in to see 5 to 7 Days
$317.63
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit HRP IHC (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Un-conjugated ELISA, WB C9orf72 antibody western blot analysis in WiDr cell lysate 0.4 mL Log in to see 2 to 3 Days
$411.13
Details

C9ORF72 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-C9ORF72 Antibodies

  1. Human Polyclonal C9ORF72 Primary Antibody for ICC, IF - ABIN4286688 : Snowden, Rollinson, Thompson, Harris, Stopford, Richardson, Jones, Gerhard, Davidson, Robinson, Gibbons, Hu, DuPlessis, Neary, Mann, Pickering-Brown: Distinct clinical and pathological characteristics of frontotemporal dementia associated with C9ORF72 mutations. in Brain : a journal of neurology 2012 (PubMed)
    Show all 4 references for ABIN4286688

  2. Human Polyclonal C9ORF72 Primary Antibody for EIA, WB - ABIN950985 : Hanna, Kruskal, Ezekowitz, Bloom, Collier: Role of macrophage oxidative burst in the action of anthrax lethal toxin. in Molecular medicine (Cambridge, Mass.) 1996 (PubMed)
    Show all 2 references for ABIN950985

More Antibodies against C9ORF72 Interaction Partners

Human Chromosome 9 Open Reading Frame 72 (C9ORF72) interaction partners

  1. The present report further suggests a possible link between intellectual disability and C9ORF72 gene mutation.

  2. The screening for the C9ORF72 expansion in a Spanish dementia cohort reveals a lower frequency of the mutation in frontotemporal lobar degeneration (FTLD) cases-compared to northern European populations-and diverse clinical manifestations in the positive cases, which include patients without a primary diagnosis of FTLD

  3. The Results of this study showed that three patients carried the C9orf72 mutation: two with ALS (show IGFALS Antibodies) and one with FTD (show FTL Antibodies) and Parkinsonism

  4. Degeneration and loss of anterior horn cells associated with expansions in C9orf72 occurs in the absence of dipeptide repeat proteins

  5. optineurin (show OPTN Antibodies) protein is present in a subset of the extramotor inclusions of C9ORF72-amyotrophic lateral sclerosis

  6. An intronic GGGGCC hexanucleotide repeat expansion in the chromosome 9 open reading frame 72 (C9orf72) gene was considered as the most common cause of amyotrophic lateral sclerosis (ALS (show IGFALS Antibodies))

  7. Pathologic expansion of the G4C2 repeat in C9orf72 is the main genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS).

  8. There appears to be a differential pattern of cerebellar atrophy in the major genetic forms of FTD (show FTL Antibodies),localized to the lobule VIIa-Crus I in the superior-posterior region of the cerebellum in C9orf72.

  9. Anti-sense DNA d(GGCCCC)n expansions in C9ORF72 form i-motifs and protonated hairpins.

  10. C9orf72 expansion is considered a major genetic cause of familial frontotemporal dementia.

C9ORF72 Antigen Profile

Protein Summary

Expansion of a hexanucleotide repeat in non-coding sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778, 21944779). Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with C9ORF72

  • chromosome Z open reading frame, human C9orf72 (C9ORF72) antibody
  • chromosome 9 open reading frame 72 (C9orf72) antibody
  • ALSFTD antibody
  • CZH9orf72 antibody
  • FTDALS antibody

Protein level used designations for C9ORF72

protein C9orf72

GENE ID SPECIES
427370 Gallus gallus
203228 Homo sapiens
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