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ATP-dependent specificity component of the Clp protease. Additionally we are shipping CLPX Antibodies (23) and and many more products for this protein.
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results illustrate that ClpX overexpression is a good and simple model to study the underlying mechanisms of the UPRmt in mammalian cells.
Loss of mitochondrial peptidase Clpp (show CLPP Proteins) leads to infertility, hearing loss plus growth retardation via accumulation of CLPX, mtDNA and inflammatory factors.
Walker B mutation in human CLPX exhibits improved interaction with the model unfolded substrate casein and several putative physiological substrates in vitro.
human ClpX, a novel mtDNA regulator, maintains mtDNA nucleoid distribution through TFAM (show TFAM Proteins) function as a chaperone rather than as a protease and its involvement in mtDNA segregation.
Results reveal that the ssrA tag interacts with different loops that form the top, middle, and lower portions of the central channel of the ClpX hexamer.
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of clpP (By similarity).
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial
, caseinolytic protease X
, ClpX caseinolytic protease X homolog
, energy-dependent regulator of proteolysis
, caseinolytic peptidase X