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anti-Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) Antibodies

F2RL2 encodes a member of the PARD protein family. Additionally we are shipping F2RL2 Kits (11) and F2RL2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
F2RL2 2151 O00254
F2RL2 14064 O08675
F2RL2 29636 Q920E1
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Top anti-F2RL2 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB F2RL2 Antibody (N-term)  western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the F2RL2 antibody detected the F2RL2 protein (arrow). F2RL2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of F2RL2 Antibody (N-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin fixed and paraffin embedded human heart tissue reacted with F2RL2 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of F2RL2 Antibody (N-term) in NCI-H292 cell line lysates (35ug/lane). This demonstrates the F2RL2 antibody detected the F2RL2 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA Immunofluorescence analysis of MCF7 cells, using F2RL2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-F2RL2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart WB Suggested Anti-F2RL2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-F2RL2 / PAR3 antibody IHC staining of human platelets. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048591 dilution 2.8-4.6 ug/ml. Anti-F2RL2 / PAR3 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN1048591 dilution 2.8-4.6 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF, ELISA 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alkaline Phosphatase (AP) IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

F2RL2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,


, , , , ,
Mouse (Murine)


Rat (Rattus)


Top referenced anti-F2RL2 Antibodies

  1. Human Polyclonal F2RL2 Primary Antibody for EIA, IHC (p) - ABIN952152 : Popović, Paskas, Zivković, Burysek, Laumonnier: Human cytomegalovirus increases HUVEC sensitivity to thrombin and modulates expression of thrombin receptors. in Journal of thrombosis and thrombolysis 2010 (PubMed)
    Show all 4 references for ABIN952152

  2. Human Polyclonal F2RL2 Primary Antibody for IHC (p), WB - ABIN656222 : Wysoczynski, Liu, Kucia, Drukala, Ratajczak: Thrombin regulates the metastatic potential of human rhabdomyosarcoma cells: distinct role of PAR1 and PAR3 signaling. in Molecular cancer research : MCR 2010 (PubMed)

  3. Human Polyclonal F2RL2 Primary Antibody for IF, ELISA - ABIN1535978 : Ishihara, Connolly, Zeng, Kahn, Zheng, Timmons, Tram, Coughlin: Protease-activated receptor 3 is a second thrombin receptor in humans. in Nature 1997 (PubMed)

More Antibodies against F2RL2 Interaction Partners

Human Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) interaction partners

  1. Knockdown of the polarity protein Par3 reversed the effects of Galpha13 (show GNA13 Antibodies) knockdown on cell-cell adhesion and proteolytic invasion in three-dimensional collagen.

  2. Par-3 plays an important role in the modulation of intestinal barrier function by regulating delivery of occludin as well as suppression of MLC phosphorylation.

  3. TFRGAP, a PAR-3 mimicking peptide significantly induced the phosphorylation of eNOS (show NOS3 Antibodies)-Thr (show TRH Antibodies)-495 with minimal phosphorylation of eNOS (show NOS3 Antibodies)-Ser (show SIGLEC1 Antibodies)-1177 with no change in nitric oxide production.

  4. Shp2 (show PTPN11 Antibodies) promotes metastasis of prostate cancer by attenuating the PAR3/PAR6 (show PARD6A Antibodies)/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition

  5. study indicated a potential molecular basis for cell growth-promoting function of PARD3 (show PARD3 Antibodies) by modulating the Hippo pathway signaling in response to cell contact and cell polarity signals

  6. PAR3-mutant proteins exhibit a relative reduction in the ability to mediate formation of tight junctions and actin-based protrusions and activate STAT3 (show STAT3 Antibodies) at cell confluence.

  7. PAR3 and aPKC control the organization of the Golgi through CLASP2 (show CLASP2 Antibodies) phosphorylation.

  8. Data show that increased partitioning defective 3 (Par-3) expression is associated with distant metastasis and poor survival rates in patients with hepatocellular carcinoma (HCC (show FAM126A Antibodies)).

  9. These data provide intriguing novel insights into the diversification of functional selectivity of protease signaling achievable by canonical and noncanonical PAR (show JTB Antibodies) activation, such as the activation of vascular-protective Tie2 (show TEK Antibodies) by noncanonical PAR3 activation.

  10. In pancreatic adenocarcinoma cells, PAR3 knockdown enhances cell adhesion. We propose this is due to increased expression of E-cadherin (show CDH1 Antibodies), leading to a greater adhesion of free-floating cells to cells bound to the surface via integrins, particularly ITGalphav.

Mouse (Murine) Coagulation Factor II (thrombin) Receptor-Like 2 (F2RL2) interaction partners

  1. Simultaneous depletion of PAR-1 (show MARK2 Antibodies) and PAR-3 almost completely inhibited epithelial-mesenchymal transition in bleomycin-induced lung fibrosis.

  2. these data point to a novel kallikrein 6 (show KLK1 Antibodies) -signaling axis in neurons that is mediated by PAR1 (show F2R Antibodies) and PAR2 (show F2RL1 Antibodies) and is positioned to contribute to neurodegeneration

  3. Par3(-/-) mice were protected against ferric chloride-induced thrombosis of mesenteric arterioles and against thromboplastin (show F3 Antibodies)-induced pulmonary embolism (protease-activated receptor-3 (PAR3)

  4. PAR3 receptors and analogues can mediate cell signaling by interaction with PAR1 (show F2R Antibodies)-type thrombin (show F2 Antibodies) receptors

  5. Crystal structures reveal the molecular basis of the cofactor function of cleaved PAR3, bound to exosite I, on recognition of PAR4 (show F2RL3 Antibodies) by the active site of thrombin (show F2 Antibodies).

F2RL2 Antigen Profile

Protein Summary

This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins\; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene.

Gene names and symbols associated with F2RL2

  • coagulation factor II (thrombin) receptor-like 2 (f2rl2) antibody
  • coagulation factor II (thrombin) receptor-like 2 (F2RL2) antibody
  • coagulation factor II (thrombin) receptor-like 2 (F2rl2) antibody
  • par-3 family cell polarity regulator (PARD3) antibody
  • par-3 partitioning defective 3 homolog (C. elegans) (PARD3) antibody
  • ASIP antibody
  • Baz antibody
  • F730031A08 antibody
  • PAR-3 antibody
  • PAR3 antibody
  • PAR3alpha antibody
  • PARD-3 antibody
  • PARD3A antibody
  • SE2-5L16 antibody
  • SE2-5LT1 antibody
  • SE2-5T2 antibody

Protein level used designations for F2RL2

proteinase-activated receptor 3 , Coagulation factor II receptor-like 2 (protease-actovated receptor 3) , protease-activated receptor 3 , proteinase-activated receptor-3 , thrombin receptor-like 2 , PAR-3 , Proteinase activated receptor 3 precursor (PAR-3) (Thrombin receptor-like 2) (Coagulation factor II receptor-like 2) , coagulation factor II receptor-like 2 , CTCL tumor antigen se2-5 , PAR3-alpha , atypical PKC isotype-specific interacting protein , atypical PKC isotype-specific-interacting protein , bazooka , par-3 family cell polarity regulator alpha , par-3 partitioning defective 3 homolog , partitioning defective 3 homolog , par3 , partitioning-defective 3 protein , partitioning-defective protein 3 homolog

GENE ID SPECIES
100148468 Danio rerio
2151 Homo sapiens
14064 Mus musculus
29636 Rattus norvegicus
512581 Bos taurus
56288 Homo sapiens
420468 Gallus gallus
477953 Canis lupus familiaris
527964 Bos taurus
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