Coagulation Factor VIII (F8) ELISA Kits

F8 encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. Additionally we are shipping Factor VIII Antibodies (342) and Factor VIII Proteins (22) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
F8 14069 Q06194
F8 2157 P00451
F8 302470  
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Top Factor VIII ELISA Kits at antibodies-online.com

Showing 10 out of 57 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Mouse 2.44 pg/mL 6.25-400 pg/mL 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Dog 31.25 ng/mL 125-8000 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$1,026.67
Details
Human 30 pg/mL 78-5.000 pg/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Pig 1.56-100 ng/mL   96 Tests Log in to see 2 to 3 Days
$867.90
Details
Human 30 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Log in to see 8 to 12 Days
$729.25
Details
Mouse 2.64 pg/mL 6.25 pg/mL - 400 pg/mL   96 Tests Log in to see 8 to 12 Days
$749.25
Details
Dog 28 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Log in to see 8 to 12 Days
$829.25
Details
Chicken 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$616.00
Details
Rabbit 18.75 pg/mL 31.25-2000 pg/mL   96 Tests Log in to see 12 to 14 Days
$616.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$616.00
Details

Top referenced Factor VIII ELISA Kits

  1. Human Factor VIII ELISA Kit for Sandwich ELISA - ABIN456987 : Wang, Yuan, Zhong, Wen, Deng, Liang, Zheng: The anticoagulant effect of PGI2S and tPA in transgenic umbilical vein endothelial cells is linked to up-regulation of PKA and PKC. in International journal of molecular sciences 2014 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for Factor VIII Interaction Partners

Zebrafish Coagulation Factor VIII (F8) interaction partners

  1. gene is flanked by factor VII (show TH ELISA Kits) and factor X genes; gene encodes a protein homologous to factor VII (show TH ELISA Kits), but lacks critical residues for factor VII (show TH ELISA Kits) activity; functions as an inhibitor of blood coagulation in biochemical assays using zebrafish or human plasmas

Mouse (Murine) Coagulation Factor VIII (F8) interaction partners

  1. Cytokine release was quantified from FVIII(-/-) splenocytes restimulated with FVIII in the absence or presence of different anti-FcgammaRIIB (CD32) Antibodies (anti-CD32 mAbs) over 6 days.

  2. results revealed localized vascular expression of FVIII and von Willebrand factor (show VWF ELISA Kits) and identified lymphatic endothelial cell as a major cellular source of FVIII in extrahepatic tissues.

  3. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (show VWF ELISA Kits) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

  4. data demonstrate that infusion of platelets containing FVIII triggers neither primary nor memory anti-FVIII immune response in FVIII(null) mice

  5. Both platelet-VWF (show VWF ELISA Kits) and plasma-VWF (show VWF ELISA Kits) are required for optimal platelet-derived FVIII gene therapy for hemophilia A in the presence of inhibitors.

  6. These data support the investigation of FVIII orthologs as treatment modalities in both the congenital and acquired FVIII inhibitor settings.

  7. Activatable bioengineered FIX molecules with FVIII-independent activity might be a promising tool for improving hemophilia A treatment, especially for patients with inhibitors.

  8. This study demonstrated that FVIIIa interacts with Low-density lipoprotein receptor-related protein 1 (show LRP1 ELISA Kits) cluster III.

  9. a fragment containing only approximately 20% of the VWF (show VWF ELISA Kits) sequence is sufficient to support FVIII stability in vivo

  10. Endothelial cells from multiple, but not all, tissues contribute to the plasma FVIII pool in the mouse.

Human Coagulation Factor VIII (F8) interaction partners

  1. FVIII endocytosis is driven by interaction with LRP1 (show LRP1 ELISA Kits)

  2. A coagulation initiating pathway is revealed in which the TF-FVIIa-nascent FXa (show F10 ELISA Kits) complex activates FVIII apart from thrombin (show F2 ELISA Kits) feedback.

  3. An in silico and in vitro approach to elucidate the impact of residues flanking the cleavage scissile bonds of FVIII by thrombin (show F2 ELISA Kits) has been presented.

  4. Of special importance is the sequential formation of disulfide bonds with different functions in structural support of VWF (show VWF ELISA Kits) multimers, which are packaged, stored and further processed after secretion. Here, all these processes are being reviewed in detail including background information on the occurring biochemical reactions. [review]

  5. The FVIII C1 domain contributes significantly to the immune response against FVIII in acquired and congenital hemophilia inhibitor patients.

  6. the existing epidemiologic investigations with an overview of the range of possible biochemical and immunologic mechanisms that may contribute to the different immune outcomes observed with plasma-derived and recombinant FVIII products.

  7. discuss potential mechanisms through which these intronic SNPs regulate ST3GAL4 (show ST3GAL4 ELISA Kits) biosynthesis and the activity that affects VWF (show VWF ELISA Kits) and FVIII

  8. the half-life of VWF (show VWF ELISA Kits) ( approximately 15 hours) appears to be the limiting factor that has confounded attempts to extend the half-life of rFVIII.

  9. results revealed localized vascular expression of FVIII and von Willebrand factor (show VWF ELISA Kits) and identified lymphatic endothelial cell as a major cellular source of FVIII in extrahepatic tissues.

  10. the results indicate that residues in the C1 and/or C2 domains of factor VIII are implicated in immunogenic factor VIII uptake, at least in vitro Conversely, in vivo, the binding to endogenous von Willebrand factor (show VWF ELISA Kits) masks the reducing effect of mutations in the C domains on factor VIII immunogenicity.

Pig (Porcine) Coagulation Factor VIII (F8) interaction partners

  1. It was concluded that VEGF and factor VIII are important growth factors associated with fetal development in pigs and are identified in all uterine segments.

  2. thrombin (show F2 ELISA Kits) stimulates transglutaminase activity in articular cartilage by directly cleaving factor XIII (show UGDH ELISA Kits) and by receptor-mediated up-regulation of factor XIII (show UGDH ELISA Kits) synthesis

  3. cupredoxin-like A1 subdomains in fVIII contain inter-species differences that are a result of selective pressure on the dissociation rate constant

Cow (Bovine) Coagulation Factor VIII (F8) interaction partners

  1. Factor VIIIc (show COX7A2 ELISA Kits) is responsible for tissue invasion during tumor progression.

Factor VIII (F8) Antigen Profile

Antigen Summary

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.

Gene names and symbols associated with Coagulation Factor VIII (F8) ELISA Kits

  • coagulation factor VIIi (f7i) antibody
  • coagulation factor VIII (F8) antibody
  • coagulation factor VIII, procoagulant component (F8) antibody
  • AHF antibody
  • Cf-8 antibody
  • Cf8 antibody
  • DXS1253E antibody
  • F8B antibody
  • F8C antibody
  • fb61d02 antibody
  • FVIII antibody
  • HEMA antibody
  • wu:fb61d02 antibody

Protein level used designations for Coagulation Factor VIII (F8) ELISA Kits

Factor VIII , procoagulant component , antihemophilic factor , coagulation factor VIII , coagulation factor VIIIc , factor VIII F8B , coagulation factor VIII, procoagulant component (hemophilia A) , factor VIII , coagulation co-factor

GENE ID SPECIES
282671 Danio rerio
14069 Mus musculus
2157 Homo sapiens
397339 Sus scrofa
403875 Canis lupus familiaris
100271720 Bos taurus
100303761 Oryctolagus cuniculus
302470 Rattus norvegicus
100359363 Ovis aries
422199 Gallus gallus
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