anti-Coagulation Factor X (F10) Antibodies

F10 encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. Additionally we are shipping Coagulation Factor X Kits (55) and Coagulation Factor X Proteins (23) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
F10 14058 O88947
F10 2159 P00742
F10 29243 Q63207
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Top anti-Coagulation Factor X Antibodies at antibodies-online.com

Showing 10 out of 140 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-F10 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>721_B cell lysate WB Suggested Anti-F10 <br /> Antibody Titration: 0.2-1 µg/mL <br /> Positive Control:.21_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from rat liver cells, using FA10 (activated heavy chain,Cleaved-Ile235) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549 cells, treated with etoposide 24uM 24h, using FA10 (light chain,Cleaved-Ala41) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of F10 antibody (C-term) (ABIN390688) in 293 cell line lysates (35 µg/lane). F10 (arrow) was detected using the purified polyclonal antibody. F10 Antibody (C-term) (ABIN390688) IHC analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, WB   0.2 mg Log in to see 6 to 8 Days
$555.50
Details
Dog Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB Western blot analysis of extracts of Raji and mouse liver cell lines, using F10 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details

F10 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Rat (Rattus) ,
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More Antibodies against Coagulation Factor X Interaction Partners

Zebrafish Coagulation Factor X (F10) interaction partners

  1. These findings as well as the prolonged survival of f10(-/-) mutants will enable us to expand our understanding of the molecular mechanisms of hemostasis, including a platform for screening variants of uncertain significance in patients with F10 deficiency and other coagulation disorders

Mouse (Murine) Coagulation Factor X (F10) interaction partners

  1. PTX2 (show PITX2 Antibodies) was identified PTX2 (show PITX2 Antibodies) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI (show MSR1 Antibodies)-mediated uptake by macrophages.

  2. annexin A2 (show ANXA2 Antibodies) contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa.

  3. Enhanced FXa and PAR2 (show F2RL1 Antibodies) exacerbate DN and that both are promising targets for preventing diabetic nephropathy.

  4. Macrophages regulate FX plasma levels in an SR-AI (show MSR1 Antibodies)-dependent manner.

  5. Factor Xa has a role in inhibiting HMGB1 (show HMGB1 Antibodies)-induced septic responses in human umbilical vein endothelial cells and in mice

  6. Selective inhibition of FXa improves the left ventricular function during CVB3-induced myocarditis and seems to be associated with an improved myocardial remodeling.

  7. Activated factor X signaling via protease-activated receptor 2 (show F2RL1 Antibodies) suppresses pro-inflammatory cytokine production from lipopolysaccharide-stimulated myeloid cells.

  8. There was no detectable increase in plasma levels of mouse FX after active-site inhibited human APC (show APC Antibodies) administration to mice overexpressing human EPCR (show PROCR Antibodies). FX does not effectively interact with EPCR (show PROCR Antibodies) in vivo, at least in regards to the mouse system.

  9. investigation of role of F10a in progression of diabetic nephropathy: data from studies using inhibitor of F10a suggest that F10a does play a role in development of proteinemia, glomerular hypertrophy, and protein deposition in kidney of db/db (show LEPR Antibodies) mice

  10. Data suggest that tissue factor (show F3 Antibodies) and factor V induction by LPS (show TLR4 Antibodies) may in part accelerate mesangioproliferative glomerulonephritis through activation of factor X and downstream proinflammatory and procoagulant mechanisms.

Human Coagulation Factor X (F10) interaction partners

  1. Data suggest that, for all coagulation proteins tested (prothrombin, factor X, activated factor VII, activated protein C), tighter binding to lipid bilayers (lower Kd) is observed as the proportion of anionic phospholipid increases. These studies were conducted in high-throughput screening using phospholipid bilayers in nanodiscs with multiplexed silicon photonic sensor (micro-ring resonator) array technology.

  2. A coagulation initiating pathway is revealed in which the TF-FVIIa-nascent FXa complex activates FVIII (show F8 Antibodies) apart from thrombin (show F2 Antibodies) feedback.

  3. Data suggest oxidized lipid vesicles with phosphatidylserine/polyunsaturated fatty acids promote inactivation of ZPI (show SERPINA10 Antibodies)-PZ complex or free ZPI (show SERPINA10 Antibodies); binding of PZ-complexed or free ZPI (show SERPINA10 Antibodies) to oxidized vesicles mediates inactivation of ZPI (show SERPINA10 Antibodies) (an inhibitor of FXa); blocking heparin- (anticoagulant-)binding site on ZPI (show SERPINA10 Antibodies) interferes with binding to lipid or PZ. (ZPI (show SERPINA10 Antibodies) = protein Z-dependent protease inhibitor (show SERPINA10 Antibodies); PZ = protein Z (show PROZ Antibodies); FXa = factor Xa)

  4. Factor Va reduced by 100-fold the apparent Kd of myosin for factor Xa (Kd approximately 0.48 nM), primarily by reducing koff, indicating formation of a stable ternary complex of myosin:Xa:Va.

  5. PTX2 (show APCS Antibodies) was identified PTX2 (show APCS Antibodies) as a novel partner for FX, and both proteins cooperated to prevent their SR-AI (show MSR1 Antibodies)-mediated uptake by macrophages.

  6. annexin A2 (show ANXA2 Antibodies) contributes to lung injury and fibrotic disease by mediating the fibrogenic actions of FXa.

  7. Individuals suffering from relapsing-remitting and secondary progressive multiple sclerosis had significantly higher prothrombin (show F2 Antibodies) and factor X levels than healthy donors, whereas levels were unchanged in primary progressive MS and neuromyelitis optica patients.

  8. Low concentrations of TF and exogenous FXIa, each too low to elicit a burst in thrombin (show F2 Antibodies) production alone, act synergistically when in combination to cause substantial thrombin (show F2 Antibodies) production.

  9. analysis of how physiological concentrations of Tissue factor pathway inhibitor (show TFPI Antibodies) inhibit FXa

  10. According to our study, compounds 1a, 1g and 1s displayed evident FXa inhibitory activity and excellent selectivity over thrombin (show F2 Antibodies) in in vitro inhibition activities studies.

Cow (Bovine) Coagulation Factor X (F10) interaction partners

  1. Data suggest factor Xa (FXa) and factor Va (FVa) compete to bind FXa on both PS model membranes and microparticles from activated platelets; this competition between dimerization/prothrombinase (show FGL2 Antibodies) complex formation appears to regulate blood coagulation.

  2. thrombin (show F2 Antibodies) and factor Xa diffusion along the heparin molecule explains the effects of extended heparin chain lengths

  3. Factor Xa (fXa), a key serine protease (show F2 Antibodies) of the coagulation system, was used as a model enzyme to test the canonical conformation hypothesis.

Coagulation Factor X (F10) Antigen Profile

Protein Summary

This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds\; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Gene names and symbols associated with F10

  • coagulation factor X (f10) antibody
  • coagulation factor X precursor (F10) antibody
  • coagulation factor X (F10) antibody
  • coagulation factor X (CpipJ_CPIJ012712) antibody
  • coagulation factor X (CpipJ_CPIJ014863) antibody
  • coagulation factor X (CpipJ_CPIJ016937) antibody
  • coagulation factor X (CpipJ_CPIJ017791) antibody
  • Coagulation factor X (fa10) antibody
  • coagulation factor X-like (F10) antibody
  • Cf10 antibody
  • F10 antibody
  • fi12c10 antibody
  • FX antibody
  • FXA antibody
  • wu:fi12c10 antibody

Protein level used designations for F10

coagulation factor 10 , coagulation factor X , vitamin K dependent serine protease , coagulation factor X preproprotein , Coagulation factor X , stuart factor , Stuart-Prower factor , factor Xa , prothrombinase , blood coagulation factor X , VAP , factor XA light chain , virus activating protease , virus-activating protease

GENE ID SPECIES
282670 Danio rerio
445942 Takifugu rubripes
452679 Pan troglodytes
714132 Macaca mulatta
790961 Ornithorhynchus anatinus
6045845 Culex quinquefasciatus
6048453 Culex quinquefasciatus
6050511 Culex quinquefasciatus
6052088 Culex quinquefasciatus
100022394 Monodelphis domestica
100137443 Papio anubis
100380501 Salmo salar
100408094 Callithrix jacchus
100453258 Pongo abelii
100471482 Ailuropoda melanoleuca
100607918 Nomascus leucogenys
14058 Mus musculus
2159 Homo sapiens
476993 Canis lupus familiaris
100008647 Oryctolagus cuniculus
29243 Rattus norvegicus
100726878 Cavia porcellus
280787 Bos taurus
395876 Gallus gallus
101118624 Ovis aries
790178 Bos taurus
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