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Cyclin G Associated Kinase (GAK) ELISA Kits

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Additionally we are shipping GAK Antibodies (93) and GAK Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
GAK 2580 O14976
GAK 231580 Q99KY4
GAK 81659 P97874
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Top GAK ELISA Kits at antibodies-online.com

Showing 5 out of 16 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$785.71
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Rat
96 Tests Log in to see 11 to 13 Days
$875.60
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Human
96 Tests Log in to see 11 to 13 Days
$875.60
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Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
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Chicken
96 Tests Log in to see 16 to 21 Days
$999.43
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More ELISA Kits for GAK Interaction Partners

Human Cyclin G Associated Kinase (GAK) interaction partners

  1. This meta-analysis suggests that GAK rs1564282 C/T polymorphism is associated with increased susceptibility to Parkinson's disease--{REVIEW}

  2. Data indicated that GBA (show GBA ELISA Kits) and TMEM175/GAK significantly alter age at onset in PD.

  3. AAK1 and GAK are critical regulators of HCV entry that function in part by activating EGFR (show EGFR ELISA Kits), AP2M1 (show AP2M1 ELISA Kits), and NUMB (show NUMB ELISA Kits), and as the molecular targets underlying the antiviral effect of sunitinib and erlotinib, respectively.

  4. The effects of rs11248051 and rs1564282 variants of GAK, and the rs3129882 variant of HLA-DRA (show HLA-DRA ELISA Kits), were investigated in Parkinson's disease patients.

  5. GAK apo (show C9orf3 ELISA Kits) structure reveals a dimeric inactive state of the catalytic domain mediated by an unusual activation segment interaction.

  6. Cyclin-G-associated kinase is a binding partners of LRRK2 (show LRRK2 ELISA Kits), a candidate genes for risk for sporadic Parkinson disease, and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system.

  7. Dominant negative mutants of IRAK4 (show IRAK4 ELISA Kits) and GAK show strong apoptotic effects in A498 cells under anoxia.

  8. rs11248060 significantly increasThis study found that the minor alleles of GAK rpopulationss1564282 and DGKQ e the risk of PD in Han Chinese .

  9. GAK as a regulator of dephosphorylation events under the control of the PP2A B'gamma subunit.

  10. study demonstrated that the rs1564282 variant in GAK (PARK17) increases the risk of Parkinson's disease in Han Chinese patients from mainland China

Mouse (Murine) Cyclin G Associated Kinase (GAK) interaction partners

  1. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  2. GAK knockout causes senescence and centrosome duplication in MEF cells.

  3. These results suggest that inhibition of GAK by gefitinib may cause pulmonary alveolar dysfunction.

  4. GAK deletion blocks development and causes lethality in adult animals by disrupting clathrin-mediated endocytosis

GAK Antigen Profile

Antigen Summary

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.

Gene names and symbols associated with GAK

  • cyclin G associated kinase (GAK) antibody
  • cyclin G associated kinase (gak) antibody
  • cyclin G associated kinase (Gak) antibody
  • D130045N16Rik antibody
  • DKFZp469F1313 antibody
  • DNAJ26 antibody
  • DNAJC26 antibody
  • gak antibody
  • MGC172462 antibody
  • si:dkeyp-1e8.1 antibody

Protein level used designations for GAK

cyclin G associated kinase , cyclin-G-associated kinase-like , auxilin-2 , cyclin-G-associated kinase , cyclin G-associated kinase

GENE ID SPECIES
100051853 Equus caballus
100171982 Pongo abelii
549104 Xenopus (Silurana) tropicalis
461048 Pan troglodytes
703406 Macaca mulatta
571705 Danio rerio
100482527 Ailuropoda melanoleuca
2580 Homo sapiens
231580 Mus musculus
81659 Rattus norvegicus
427291 Gallus gallus
479133 Canis lupus familiaris
511296 Bos taurus
101106688 Ovis aries
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