You are viewing an incomplete version of our website. Please click to reload the website as full version.

Cyclin-Dependent Kinase 14 Proteins (CDK14)

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Additionally we are shipping CDK14 Antibodies (75) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CDK14 5218 O94921
CDK14 18647 O35495
Rat CDK14 CDK14 362316  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top CDK14 Proteins at antibodies-online.com

Showing 10 out of 12 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,179.00
Details
Yeast Callithrix jacchus His tag   1 mg Log in to see 56 to 66 Days
$3,179.00
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,215.67
Details
Yeast REACT_Titi monkey His tag   1 mg Log in to see 56 to 66 Days
$3,265.17
Details
Yeast Dasypus novemcinctus His tag   1 mg Log in to see 56 to 66 Days
$3,318.33
Details
Yeast Rabbit His tag   1 mg Log in to see 56 to 66 Days
$3,318.33
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

CDK14 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

More Proteins for Cyclin-Dependent Kinase 14 (CDK14) Interaction Partners

Human Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. PFTK1 overexpression promoted proliferation, migration and invasion of gastric cancer cells, while PFTK1 knockdown led to the opposite results.

  2. Knockdown of PFTK1 increases E-cadherin (show CDH1 Proteins) expression, decreases vimentin (show VIM Proteins) expression and inhibits migration of glioma cells.

  3. Up-regulated PFTK1 might promote breast cancer progression.

  4. Cigarette smoke down regulates CDK14 levels and impairs Wnt (show WNT2 Proteins) signaling.

  5. findings indicate that brain PP-1I associates with and is regulated by the associated protein kinases C-TAK1 (show MARK3 Proteins) and PFTK1

  6. binding of CCNY (show CCNY Proteins) to 14-3-3 (show YWHAQ Proteins) significantly enhanced the association between CCNY (show CCNY Proteins) and CDK14

  7. Human cyclin Y (CCNY (show CCNY Proteins)) is a phosphoprotein in vivo and phosphorylation of CCNY (show CCNY Proteins) by CDK14 triggers its ubiquitination and degradation.

  8. in patients with oesophageal squamous cell carcinoma 5-year overall survival rate was poorer in patients positive for PFTK1 than those with negative expression; uni- and multivariate analyses identified PFTK1 as an independent marker of prognosis

  9. Taken together, our data propose a novel, oncogene (show RAB1A Proteins)-tumor suppressor interplay, where oncogenic PFTK1 confers HCC (show FAM126A Proteins) cell motility through inactivating the actin-binding motile suppressing function of TAGLN2 (show TAGLN2 Proteins) via phosphorylation.

  10. Novel biological cascade that involved the phosphorylation activation of CaD by PFTK1 kinase in promoting formation of actin stress fibers.

Mouse (Murine) Cyclin-Dependent Kinase 14 (CDK14) interaction partners

  1. Cigarette smoke down regulates CDK14 levels and impairs Wnt (show WNT2 Proteins) signaling.

  2. may be a key regulator for thyrotropin-releasing hormone (TRH (show TRH Proteins)) action in the cerebellum through the NO-cGMP pathway

CDK14 Protein Profile

Protein Summary

Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

Gene names and symbols associated with CDK14

  • cyclin-dependent kinase 14 (CDK14)
  • PFTAIRE protein kinase 1 (PFTK1)
  • cyclin-dependent kinase 14 (Cdk14)
  • cyclin-dependent kinase 14 (cdk14)
  • mKIAA0834 protein
  • pftaire1 protein
  • pftk1 protein

Protein level used designations for CDK14

PFTAIRE protein kinase 1 , cell division protein kinase 14 , hPFTAIRE1 , serine/threonine-protein kinase PFTAIRE-1 , Cell division protein kinase 14

GENE ID SPECIES
463522 Pan troglodytes
703442 Macaca mulatta
100137460 Papio anubis
100173505 Pongo abelii
5218 Homo sapiens
18647 Mus musculus
362316 Rattus norvegicus
100328634 Oryctolagus cuniculus
420546 Gallus gallus
475223 Canis lupus familiaris
100515962 Sus scrofa
784403 Bos taurus
101424147 Dasypus novemcinctus
100391008 Callithrix jacchus
444781 Xenopus laevis
Selected quality suppliers for CDK14 Proteins (CDK14)
Did you look for something else?