Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
CYB5R3 encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. Additionally we are shipping Cytochrome B5 Reductase 3 Antibodies (135) and Cytochrome B5 Reductase 3 Kits (16) and many more products for this protein.
Showing 10 out of 16 products:
Human CYB5R3 Protein expressed in Wheat germ - ABIN1350883
Havemeyer, Bittner, Wollers, Mendel, Kunze, Clement: Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme. in The Journal of biological chemistry 2006
Data suggest that cytochrome b5 (CYB5 (show CYB5A Proteins)) and cytochrome b5 reductase 3 (CYB5R3) can reduce human cytoglobin (CYGB (show CYGB Proteins)) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin (show HBB Proteins) and myoglobin (show MB Proteins); the three proteins (CYB5 (show CYB5A Proteins)+CYB5R3+CYGB (show CYGB Proteins)) appear to constitute a metabolon involved in generation of nitric oxide.
HASF (C3orf58) is a novel ligand of IGF1R (show IGF1R Proteins).
CYB5R3 promotes colonization and metastasis formation and is a prognostic marker of disease-free and overall survival in estrogen receptor (show ESR1 Proteins)-negative breast cancer.
Variants in CYB5A (show CYB5A Proteins) and CYB5R3 should be considered in the evaluation of breast cancer risk in African American women.
Genetic variation in CYB5R3 is associated with methemoglobin levels in preterm infants receiving nitric oxide therapy.
The results unveil a potential mechanism of action by which CYB5R3 deficiency contributes to the pathophysiological underpinnings of neurological disorders in RHM patients.
Dapsone-associated methemoglobinemia in a patient with slow NAT2*5B haplotype and impaired cytochrome b5 reductase activity
A comprehensive overview of the study of structure and function of human cytochrome b5 reductase.
Data indicate that mitochondrial amidoxime reducing components 1 and 2 together with the electron transport proteins NADH-cytochrome b5 reductase (show CYB5RL Proteins) (CYB5R) and cytochrome b5 (CYB5 (show CYB5A Proteins)) catalyze the reduction of N-hydroxylated compounds such as amidoximes.
Population frequency and age of c.806C > T mutation in CYB5R3 gene as cause of recessive congenital methemoglobinemia in Yakutia.
Nucleation is achieved by a mechanism involving APC (show APC Proteins)-B dimerization and recruitment of multiple actin monomers. Further, APC (show APC Proteins)-B nucleation activity is synergistic with its in vivo binding partner, the formin (show FMN1 Proteins) mDia1
an N-terminal domain spanning residues 129-369(DID) is sufficient for auto-inhibition, but alone is not sufficient for RhoA (show RHOA Proteins) relief of auto-inhibition, suggesting that sequences N-terminal to DID are important to RhoA (show RHOA Proteins) binding.
Dia1 is required for the formation of the actin coat around endosomes downstream of RhoB, connecting membrane trafficking with the regulation of actin dynamics.
Dia1 and IQGAP1 interact in cell migration and phagocytic cup formation.
This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.
NADH-cytochrome b5 reductase 3
, diaphorase 1
, NADH-cytochrome b5 reductase
, cytochrome b5 reductase 3
, Golgi protein GoPro49
, UPF0672 protein C3orf58
, deleted in autism 1
, deleted in autism protein 1
, NADH-cytochrome b5 reductase 3 membrane-bound form
, NADH-cytochrome b5 reductase 3 soluble form
, diaphorase 1 (NADH)
, Diaphorase (NADH) (cytochrome b-5 reductase)