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Cytochrome B5 Reductase 4 Proteins (CYB5R4)

NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A\; MIM 613218) and CYB5 reductase (CYB5R3\; MIM 613213) (Zhu et al., 1999 [PubMed 10611283]).[supplied by OMIM, Jan 2010].. Additionally we are shipping Cytochrome B5 Reductase 4 Antibodies (47) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYB5R4 51167 Q7L1T6
CYB5R4 266690 Q3TDX8
CYB5R4 171015 Q68EJ0
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Top Cytochrome B5 Reductase 4 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,479.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYB5R4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Cytochrome B5 Reductase 4 (CYB5R4) Interaction Partners

Human Cytochrome B5 Reductase 4 (CYB5R4) interaction partners

  1. Cytosolic localization of NADH cytochrome b (show MT-CYB Proteins) oxidoreductase (show TXNRD1 Proteins)

  2. data provide first evidence for natural mutations in NCB5OR gene resulting in decreased protein levels and hence having potential implications in human pathology.

  3. Mutation in cytochrome b5 reductase (show CYB5R3 Proteins) is associated with developmental delay and severe neurological problems.

  4. Study of the individual cytochrome b5 (show CYB5A Proteins) and cytochrome b5 reductase (show CYB5R3 Proteins) domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain.

  5. NCB5OR is a novel soluble NAD(P)H (show NQO1 Proteins) reductase localized in the endoplasmic reticulum

Mouse (Murine) Cytochrome B5 Reductase 4 (CYB5R4) interaction partners

  1. In livers of HRN mice Cyp1a1 (show CYP1A1 Proteins), cytochrome b5 (show CYB5A Proteins) and mEH (show EPHX1 Proteins) can effectively activate BaP (show PHB2 Proteins) to DNA binding species, even in the presence of very low amounts of P450 (show POR Proteins) oxidoreductase (show HSD17B6 Proteins).

  2. FFA accumulation and catabolism and oxidative stress are major consequences of Ncb5or deficiency in liver.

  3. Study of the individual cytochrome b5 (show CYB5A Proteins) and cytochrome b5 reductase (show CYB5R3 Proteins) domains of Ncb5or reveals a unique heme pocket and a possible role of the CS domain.

  4. Onset of hyperglycemia in the Chop (show DDIT3 Proteins)(-/-);Ncb5or(-/-) mice was delayed two weeks beyond that observed in Chop (show DDIT3 Proteins)(+/+);Ncb5or(-/-) mice.

  5. NCB5OR is a novel soluble NAD(P)H (show NQO1 Proteins) reductase localized in the endoplasmic reticulum

  6. Data suggest that NCB5OR appears to play a critical role in protecting pancreatic beta cells against oxidant stress.

  7. The data presented here identify and characterize the previously unknown promoter of Ncb5or, a reductase critical for beta-cell survival.

  8. Data suggest that NCB5OR does not appear to be involved in ER stress, although it may be involved in maintaining or regulating the redox status in beta-cells.

  9. Ncb5or loss results in impaired fatty acid desaturation, lipoatrophy, and diabetes

Cytochrome B5 Reductase 4 (CYB5R4) Protein Profile

Protein Summary

NCB5OR is a flavohemoprotein that contains functional domains found in both cytochrome b5 (CYB5A\; MIM 613218) and CYB5 reductase (CYB5R3\; MIM 613213) (Zhu et al., 1999

Gene names and symbols associated with CYB5R4

  • cytochrome b5 reductase 4 (CYB5R4)
  • Cytochrome b5 reductase 4 (TGas070l21.1)
  • cytochrome b5 reductase 4 (LOAG_02505)
  • cytochrome b5 reductase 4 (Tsp_02207)
  • cytochrome b5 reductase 4 (Cyb5r4)
  • cytochrome b5 reductase 4 (cyb5r4)
  • 2810034J18Rik protein
  • b5&b5R protein
  • b5+b5R protein
  • b5/b5r protein
  • b5b5r protein
  • C79736 protein
  • cb5/cb5R protein
  • Cb5cb5r protein
  • cyb5r4 protein
  • dJ676J13.1 protein
  • im:4727699 protein
  • Ncb5or protein
  • RP4-676J13.1 protein
  • zgc:112177 protein

Protein level used designations for CYB5R4

cytochrome b5 reductase 4 , N-terminal cytochrome b5 and cytochrome b5 oxidoreductase domain-containing protein , NADPH cytochrome B5 oxidoreductase , cytochrome b-type NAD(P)H oxidoreductase , flavohemoprotein b5+b5R , flavohemoprotein b5/b5R , cb5/cb5R , b5+b5R , ncb5or

GENE ID SPECIES
421837 Gallus gallus
549510 Xenopus (Silurana) tropicalis
9939891 Loa loa
10907672 Trichinella spiralis
51167 Homo sapiens
266690 Mus musculus
171015 Rattus norvegicus
533608 Bos taurus
553685 Danio rerio
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