anti-Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) Antibodies

CYP2C19 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping CYP2C19 Kits (17) and CYP2C19 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
CYP2C19 1557 P33261
CYP2C19 510380  
CYP2C19    
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Top anti-CYP2C19 Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from 293 cells, using Cytochrome P450 2C19 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of CYP2C19 Antibody (Center) (ABIN390665) in Jurkat cell line lysates (35 µg/lane). CYP2C19 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using CYP2C19 Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of CYP2C19 Antibody (N-term) (ABIN652231) in HL-60 cell line lysates (35 µg/lane). CYP2C19 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with GPD1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of Cytochrome P450 2C19 staining in Hela cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a hidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Cytochrome P450 2C19 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Immunohistochemistry analysis of CYP2C19 antibody in paraffin-embedded human liver carcinoma tissue. Western blot analysis of CYP2C19 antibody in extracts from 293 cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 7 to 9 Days
$478.50
Details

CYP2C19 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human


Cow (Bovine)


Monkey


Top referenced anti-CYP2C19 Antibodies

  1. Human Polyclonal CYP2C19 Primary Antibody for ELISA, WB - ABIN1534386 : Romkes, Faletto, Blaisdell, Raucy, Goldstein: Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily. in Biochemistry 1991 (PubMed)
    Show all 2 references for 1534386

  2. Human Polyclonal CYP2C19 Primary Antibody for EIA, IHC (p) - ABIN452898 : Shuldiner, OConnell, Bliden, Gandhi, Ryan, Horenstein, Damcott, Pakyz, Tantry, Gibson, Pollin, Post, Parsa, Mitchell, Faraday, Herzog, Gurbel: Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. in JAMA : the journal of the American Medical Association 2009 (PubMed)

  3. Cow (Bovine) Polyclonal CYP2C19 Primary Antibody for WB - ABIN2777003 : Ji, Olson, Zhang, Hildebrandt, Wang, Ingle, Fredericksen, Sellers, Miller, Dixon, Brauch, Eichelbaum, Justenhoven, Hamann, Ko, Brüning, Chang-Claude, Wang-Gohrke, Schaid, Weinshilboum: Breast cancer risk reduction and membrane-bound catechol O-methyltransferase genetic polymorphisms. in Cancer research 2008 (PubMed)

More Antibodies against CYP2C19 Interaction Partners

Human Cytochrome P450, Family 2, Subfamily C, Polypeptide 19 (CYP2C19) interaction partners

  1. The poor metabolizer (PM) group had the lowest metabolic ratio and exhibited the highest area under the curve (AUC) for omeprazole among the CYP2C19 phenotype groups.

  2. The carriage of the cytochrome P450 (show CYP Antibodies) CYP2C19 681A allele rather than platelet receptor gene polymorphisms increased extent of platelet aggregation induced by dual antiplatelet therapy in patients with Coronary heart disease .

  3. coadministration, voriconazole AUC and Cmin decreased by 33% and 39% respectively, in CYP2C19 extensive-metabolizers, whereas voriconazole Cmax and AUC increased 4.4-fold and 5.6-fold respectively, in poor-metabolizers

  4. individuals with both the CYP2C19*2 allele and hypertension are at high risk of Clopidogrel Resistance during anti-thrombosis therapy.

  5. NXT (show NXT1 Antibodies) leaded to a significant enhancement of the CYP2C19 catalytic activity in PXR (show NR1I2 Antibodies)-transfected HepG2 cells

  6. The aim of this study was to clarify the catalytic activities of 31 CYP2C19 alleles on the oxidative in vitro metabolism of methadone. Methadone, as a CYP2C19-specific substrate, was used to systematically analyze the enzymatic characteristics of 31 CYP2C19 alleles found in the Chinese population, and offer valuable information relevant to the personalized medicine for CYP2C19-metabolized drugs in China.

  7. apart from the established association of the CYP2C19 *2 and *3 LOF alleles with high on-treatment platelet reactivity (HTPR), haplotypes of P2RY12 rs6798347, rs6787801, rs6801273, and rs6785930 rather than rs2046934 (T744C) that related to pharmacodynamics of clopidogrel in patients with ACS were independently associated with HTPR

  8. CYP2C19 poor metabolizer genotype may be a new candidate risk factor for coronary microvascular disorder via inflammation exclusively in the female population.

  9. Poor metabolizer CYP2C19 variants are associated with microvascular angina.

  10. Variant genotypes of CYP2C19 are associated with an increased risk of esophageal squamous cell carcinoma in Kashmir, India.

CYP2C19 Antigen Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24.

Gene names and symbols associated with CYP2C19

  • cytochrome P450, family 2, subfamily C, polypeptide 19 (CYP2C19) antibody
  • CPCJ antibody
  • CYP2C antibody
  • P450C2C antibody
  • P450IIC19 antibody

Protein level used designations for CYP2C19

cytochrome P450 2C , (R)-limonene 6-monooxygenase , (S)-limonene 6-monooxygenase , (S)-limonene 7-monooxygenase , CYPIIC17 , CYPIIC19 , S-mephenytoin 4-hydroxylase , cytochrome P-450 II C , cytochrome P450 2C19 , cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 19 , cytochrome P450-11A , cytochrome P450-254C , flavoprotein-linked monooxygenase , mephenytoin 4'-hydroxylase , mephenytoin 4-hydroxylase , microsomal monooxygenase , xenobiotic monooxygenase

GENE ID SPECIES
510380 Bos taurus
1557 Homo sapiens
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