You are viewing an incomplete version of our website. Please click to reload the website as full version.

Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Proteins (CYP51A1)

CYP51A1 encodes a member of the cytochrome P450 superfamily of enzymes. Additionally we are shipping Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Antibodies (67) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CYP51A1 13121 Q8K0C4
Rat CYP51A1 CYP51A1 25427 Q64654
CYP51A1 1595 Q16850
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

CYP51A1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) Interaction Partners

Mouse (Murine) Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) interaction partners

  1. Our Cyp51 LKO model shows that steatosis appears with dietary fats in the absence of dietary cholesterol and its synthesis, while a block in the cholesterol pathway leads to NASH (show SAMSN1 Proteins)-like features

  2. germ cell-specific ablation of Cyp51, leading to lack of MAS (show MAS1 Proteins), did not affect testicular morphology, daily sperm production, or reproductive performance in males.

  3. Cyp51 knock-out mice provide evidence that Cyp51 is essential for embryogenesis and present a potential animal model for studying ABS syndrome in humans.

  4. Findings suggest that FSH (show BRD2 Proteins), partially at least, employs CYP51, and therefore the MAS (show MAS1 Proteins) pathway, to initiate oocyte meiosis.

  5. localization of CYP51 in testis and ovary shows Leydig cells and acrosomes of spermatids express the highest levels

  6. Demethylation of lanosterol to FF-MAS (show MAS1 Proteins) by the acrosomal lanosterol 14 alpha-demethylase enzyme complex demonstrates for the first time the ability of ejaculate sperm to synthesize meiosis-activating sterols.

  7. A gene participating in cholesterol bisynthesis (CYP51) is regulated in an immediate early (show JUN Proteins) fashion, which influences sterol profile of the cell.

  8. there was a cholesterol levels link-modulation system between cholesterol synthetic pathway through CYP51 and cholesterol transport pathway through , low-density lipoprotein receptor (show LDLR Proteins) in vivo

  9. These data indicate that Crem-dependent regulation of Cyp51 in the liver results in circadian expression of this gene.

  10. Lanosterol 14alpha-demethylase (LDM) is closely related to mouse embryo implantation and can be upregulated by oestrogen.

Human Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) interaction partners

  1. Acyl-Carbon Bond Cleaving Cytochrome P450 Enzymes: CYP17A1 (show CYP17A1 Proteins), CYP19A1 (show CYP19A1 Proteins) and CYP51A1.

  2. Suggest that GDF9 (show GDF9 Proteins), possibly with FSH (show BRD2 Proteins), may play significant roles in the regulation of cholesterol biosynthesis and the expression of CYP51A1 in granulosa cells which might be a predictor for unfertilization.

  3. Data show that forkhead transcription factor 4 (FoxO4) interacts with sterol regulatory element binding protein (SREBP)2 and hypoxia inducible factor (HIF)2alpha to modulate lanosterol 14alpha demethylase (CYP51) promoter activity.

  4. Our results indicate a new link between a cholesterol synthesis gene CYP51A1 and pregnancy pathologies.

  5. The studied azoles selectively interacted with human cytochrome P450 51A1, which showed the highest affinity towards ketoconazole.

  6. Low nucleotide variability of CYP51A1 is seen in cholesterol and bile acid synthesis and xenobiotic metabolism pathways.

  7. The new CYP51A1 inhibitor 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LEK-935) on the proteome of primary human hepatocytes were analyzed.

  8. A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene.

  9. the liver X receptor alpha (show NR1H3 Proteins) directly silencing the expression of two key cholesterologenic enzymes (lanosterol 14alpha-demethylase (CYP51A1), and squalene synthase (farnesyl diphosphate farnesyl transferase 1 (show FDFT1 Proteins))) via novel negative LXR (show NR1H3 Proteins) DNA response elements

Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 (CYP51A1) Protein Profile

Protein Summary

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with CYP51A1

  • cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51A1)
  • cytochrome P450, family 51 (cyp51)
  • cytochrome P450, family 51, subfamily A, polypeptide 1 (cyp51a1)
  • cytochrome P450, family 51 (Cyp51)
  • cytochrome P450, family 51, subfamily A, polypeptide 1 (CYP51)
  • AI426508 protein
  • CP51 protein
  • CYP51 protein
  • CYP51A1 protein
  • CYPL1 protein
  • CYPLI protein
  • LDM protein
  • P450-14DM protein
  • P450L1 protein
  • P450LI protein
  • RATCP14DM protein

Protein level used designations for CYP51A1

CYPLI , Cytochrome P450 51A1 , LDM , cytochrome P450-14DM , cytochrome P45014DM , cytochrome P450LI , lanosterol 14-alpha demethylase , sterol 14-alpha demethylase , cytochrome P450, family 51, subfamily A, polypeptide 1 , 14 alpha demethylase , lanosterol 14-demethylase , cytochrome P450 51A1 , cytochrome P450, 51 , lanosterol 14-alpha-demethylase , Cytochrom P450 Lanosterol 14 alpha-demethylase , P450-14DM , P45014DM , P450LI , cytochrome P450 Lanosterol 14 alpha-demethylase , cytochrome P450, subfamily 51 , cytochrome P450, 51 (lanosterol 14-alpha-demethylase) , cytochrome P450 51

GENE ID SPECIES
100171776 Pongo abelii
414330 Strongylocentrotus purpuratus
420548 Gallus gallus
463527 Pan troglodytes
548948 Xenopus (Silurana) tropicalis
100037098 Xenopus laevis
13121 Mus musculus
25427 Rattus norvegicus
1595 Homo sapiens
505060 Bos taurus
403334 Sus scrofa
475225 Canis lupus familiaris
Selected quality suppliers for Cytochrome P450, Family 51, Subfamily A, Polypeptide 1 Proteins (CYP51A1)
Did you look for something else?