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This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Additionally we are shipping DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 53 Proteins (2) and many more products for this protein.
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DDX53 promotes stem cell-like properties, autophagy, and confers resistance to anti-cancer drugs in breast cancer cells.
Results provide evidence that miR (show MLXIP Antibodies)-30a forms a positive feedback loop with CAGE to regulate the expression of p53 (show TP53 Antibodies) confering resistance to anti-cancer drugs.
miR (show MLXIP Antibodies)-217-CAGE feedback loop serves as a target for overcoming resistance to various anti-cancer drugs, including EGFR (show EGFR Antibodies) and HER2 (show ERBB2 Antibodies) inhibitors.
Results show the direct regulation of CAGE expression by HDAC3 (show HDAC3 Antibodies) and that HDAC3 (show HDAC3 Antibodies)-CAGE axis regulates the activation of EGFR (show EGFR Antibodies). HDAC3 (show HDAC3 Antibodies) targets CAGE to regulate the tumorigenic potential and angiogenic potential of cancer cells.
CAGE induced the interaction between histone deacetylase 2 (HDAC2 (show HDAC2 Antibodies)) and Snail (show SNAI1 Antibodies), which exerted a negative effect on p53 (show TP53 Antibodies) expression in neoplastic cells; CAGE confers drug resistance by regulating expression of p53 (show TP53 Antibodies) through HDAC2 (show HDAC2 Antibodies).
CAGE promotes motility of cancer cells through activation of focal adhesion kinase (FAK).
This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family. Other members of this protein family participate in ATP-dependent RNA unwinding.
DEAD box protein 53
, DEAD-box protein CAGE
, cancer/testis antigen 26
, cancer-associated gene protein
, probable ATP-dependent RNA helicase DDX53
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 53
, DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
, probable ATP-dependent RNA helicase DDX53-like