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May be involved in transcriptional regulation as a transcriptional corepressor. Additionally we are shipping DEPDC1 Antibodies (44) and many more products for this protein.
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DEPDC1 mRNA and protein expression levels were dramatically increased in prostate cancer tissues and cell lines. Overexpression of DEPDC1 promoted, but depletion of DEPDC1 inhibited cell proliferation by regulating the G1-S phase cell cycle transition.
miR (show MLXIP Proteins)-130a is an epigenetically regulated miRNA involved in regulation of key molecular and phenotypic features of prostate carcinogenesis, acting as a tumour suppressor miRNA by targeting SEC23B (show SEC23B Proteins) and DEPDC1.
Results suggest that protocadherin 10 (PCDH10)-Dishevelled, EGL-10 and Pleckstrin domain containing 1 (DEPDC1)-caspase signaling may be a novel regulatory axis in endometrial endometrioid carcinoma (EEC) development.
DEPDC1, plays a pivotal role in the regulation of proper mitotic progression.
High DEPDC1 mRNA expression is associated with hepatocellular carcinoma/
DEPDC1 regulates vincristine-induced cell death by promoting JNK (show MAPK8 Proteins)-dependent degradation of the BCL-2 (show BCL2 Proteins) family protein MCL1 (show MCL1 Proteins).
Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells.
Coimmunoprecipitation and immunocytochemistry revealed that DEPDC1 interacted and colocalized with zinc finger transcription factor (show OSR1 Proteins) ZNF224 (show ZNF224 Proteins), a known transcriptional repressor.
May be involved in transcriptional regulation as a transcriptional corepressor. The DEPDC1A-ZNF224 complex may play a critical role in bladder carcinogenesis by repressing the transcription of the A20 gene, leading to transport of NF-KB protein into the nucleus, resulting in suppression of apoptosis of bladder cancer cells.
DEP domain-containing protein 1A
, DEP domain containing 1
, DEP domain-containing protein 1A-like
, cell cycle control protein SDP35
, DEP domain containing 1a
, DEP domain containing protein 1