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May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Additionally we are shipping DET1 and DDB1 Associated 1 Proteins (8) and many more products for this protein.
Showing 10 out of 44 products:
Dog (Canine) Polyclonal DDA1 Primary Antibody for ELISA - ABIN4267544
Olma, Roy, Le Bihan, Sumara, Maerki, Larsen, Quadroni, Peter, Tyers, Pintard: An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases. in Journal of cell science 2009
the c-Abl (show ABL1 Antibodies) non-receptor kinase phosphorylates DDB1 (show DDB1 Antibodies) at residue Tyr (show TYR Antibodies)-316 to recruit a small regulatory protein, DDA1, leading to increased substrate ubiquitination
PCIA1 gene expression correlates with tumor formation, invasion and metastasis
Cells depleted of Dda1 spontaneously accumulated double-stranded DNA breaks in a similar way to Cul4A-, Cul4B- or Wdr23-depleted cells, indicating that Dda1 interacts physically and functionally with cullin-RING E3 ligases complexes.
Data describe the characterization of the testis-specific (show AIF1 Antibodies) effects of absence of the high-affinity thiamin transporter, Tht1 (show SLC19A2 Antibodies).
Pancreatic beta cells and islets take up thiamine by a regulated THTR1/2-mediated process.
May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD- E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins (By similarity).
DET1- and DDB1-associated protein 1
, cross-immune reaction antigen PCIA1
, placenta cross-immune reaction antigen 1
, thiamine transporter 1