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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3B Proteins (5) and DNMT3B Kits (3) and many more products for this protein.
Showing 10 out of 116 products:
Human Monoclonal DNMT3B Primary Antibody for ChIP, FACS - ABIN252478
Santoro, Li, Grummt: The nucleolar remodeling complex NoRC mediates heterochromatin formation and silencing of ribosomal gene transcription. in Nature genetics 2002
Show all 93 references for ABIN252478
Human Polyclonal DNMT3B Primary Antibody for ICC, IF - ABIN151734
Robert, Morin, Beaulieu, Gauthier, Chute, Barsalou, MacLeod: DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. in Nature genetics 2003
Show all 14 references for ABIN151734
Human Polyclonal DNMT3B Primary Antibody for IHC (p), WB - ABIN387884
Lu, Markowetz, Unwin, Leek, Airoldi, MacArthur, Lachmann, Rozov, Maayan, Boyer, Troyanskaya, Whetton, Lemischka: Systems-level dynamic analyses of fate change in murine embryonic stem cells. in Nature 2009
Show all 13 references for ABIN387884
Human Monoclonal DNMT3B Primary Antibody for ChIP, WB - ABIN2668954
Castro, Breiling, Luetkenhaus, Ceteci, Hausmann, Kress, Lyko, Rudel, Rapp: MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma. in Molecular cancer research : MCR 2013
Show all 2 references for ABIN2668954
Human Polyclonal DNMT3B Primary Antibody for EIA, IHC (p) - ABIN356569
Stipani, Cappello, Daddabbo, Natuzzi, Miniero, Stipani, Palmieri: The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents. in Biochemistry 2001
Human Polyclonal DNMT3B Primary Antibody for IF (p), IHC (p) - ABIN727623
Zhao, Hou, Chen, Shao, Zhu, Bu, Gu, Li, Zhang, Du, Fu, Kong, Luo, Long, Li, Deng, Zhao, Cen: Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation. in Neurobiology of disease 2015
Human Polyclonal DNMT3B Primary Antibody for IF, IHC - ABIN1534163
Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002
Chicken Polyclonal DNMT3B Primary Antibody for WB - ABIN2783648
Boland, Christman: Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA. in Journal of molecular biology 2008
dnmt7 specifically methylates no tail gene in the genome
Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (show HELLS Antibodies) content are rather a function of time, and not a genetic component.
Downregulation of DNMT3B, one of the targets identified using this method, radiosensitizes cancer cells by disturbing multiple DNA damage responses.
The HBVX gene upregulated the mRNA and protein expression levels of DNMT3A (show DNMT3A Antibodies)/3B, downregulated the expression of SOCS1 (show SOCS1 Antibodies) and increased SOCS1 (show SOCS1 Antibodies) gene promoter CpG island methylation.
Our results demonstrate DNMT3B4-del as a critical factor in developing aberrant DNA methylation (show HELLS Antibodies) patterns during lung tumorigenesis and suggest that DNMT3B4-del may be a target for lung cancer prevention.
Results suggested that the DNMT3B -149C/T polymorphism is associated with a genetic susceptibility for developing LSCC in a Chinese population.
Data indicate an epigenetic prognostic signature in glioblastomas based on expression of polycomb (show CBX2 Antibodies) repressive complex 2 (EZH2 (show EZH2 Antibodies)), DNA-methyltransferases DNMT1 (show DNMT1 Antibodies) and 3B which can be used easily in routine neuropathology practice.
miR (show MLXIP Antibodies)-124 and miR (show MLXIP Antibodies)-506 inhibit progression and increase sensitivity to chemotherapy by targeting DNMT3B and DNMT1 (show DNMT1 Antibodies) in colorectal carcinoma.
Increasing DNA methylation (show HELLS Antibodies) in the gene-coding area of DNMT3B was associated with higher risk of colorectal adenomas (OR = 1.34; 95% CI: 1.01-1.79 per SD).
To correlate DNMTs expression with DNA methylation (show HELLS Antibodies), DNMT1 (show DNMT1 Antibodies), DNMT3A (show DNMT3A Antibodies) and DNMT3B mRNA levels in 5 colorectal cancer cell lines; results suggest that cellular DNMT (show DNMT1 Antibodies) expression is positively correlated with global DNA methylation (show HELLS Antibodies) level but not with regional DNA hypermethylation at each locus.
Deregulated Dnmt3b targets have prognostic impact in acute myeloid leukemia patients.
DNMT1 (show DNMT1 Antibodies), DNMT3B, and EZH2 (show EZH2 Antibodies) were expressed at significantly higher levels in tumor vs. normal tissues.
The epiblast expressed epithelial markers, MUC1 (show MUC1 Antibodies) and E-CADHERIN (show CDH1 Antibodies), and the pluripotency markers, DNMT3B and CRIPTO (show TDGF1 Antibodies).
Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.
The expression levels of DNMT3a (show DNMT3A Antibodies) and DNMT3b were associated with several beef quality traits.
High levels of Dnmt3b expression prolong leukemia latency.
The expression of DNMT1 (show DNMT1 Antibodies) and DNMT3b was decreased at 1 mT, and 50 Hz ELF (show SPTBN1 Antibodies)-EMF can increase the expression...the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF (show SPTBN1 Antibodies)-EMF exposure
DKO cardiomyocytes showed virtual absence of targeted Dnmt3a (show DNMT3A Antibodies) and Dnmt3b mRNA transcripts.
An unexpected oncogenic role for Dnmt3a (show DNMT3A Antibodies) in MTCL through methylation-independent repression of Dnmt3b.
we report that cardiac specific deletion of Dnmt3b, the predominant DNA methyltransferase (show DNMT1 Antibodies) in adult mouse hearts, leads to an accelerated progression to severe systolic insufficiency and myocardial thinning without a preceding hypertrophic response.
These results indicated a role for the miR29b-Dnmt3a (show DNMT3A Antibodies)/3b-DNA methylation (show HELLS Antibodies) axis in mouse early embryonic development, and we provide evidence that miR29b is indispensable for mouse early embryonic development
data suggest that Dnmt3a (show DNMT3A Antibodies) and Dnmt3b are critical to regulate the onset of Igkappa light chain rearrangement during early B-cell development
Study reveals that the DNMT3 de novo methyltransferases DNMT3A (show DNMT3A Antibodies) and DNMT3B play both redundant and specific functions in the establishment of DNA methylation (show HELLS Antibodies) in the mouse embryo.
Dnmt3b-deficient cells can contribute to the male and female germ-lines in chimeric mice and can produce normal progeny, establishing that Dnmt3b is dispensable for mouse gametogenesis and imprinting.
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
DNA (cytosine-5)-methyltransferase 3B
, DNA (cytosine-5-)-methyltransferase 3 beta
, DNA cytosine-5 methyltransferase 3 beta
, DNA (cytosine-5)-methyltransferase 3B-like
, DNA methyl transferase beta
, DNA methyltransferase 3B
, DNA MTase HsaIIIB
, DNA methyltransferase HsaIIIB
, DNA (cytosine-5-)-methyltransferase 3 beta, like
, DNA (cytosine-5-)-methyltransferase 7
, DNA MTase MmuIIIB
, DNA methyltransferase MmuIIIB