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anti-DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Antibodies

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Additionally we are shipping DNMT3B Proteins (5) and DNMT3B Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNMT3B 1789 Q9UBC3
DNMT3B 444985  
DNMT3B 13436 O88509
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Top anti-DNMT3B Antibodies at antibodies-online.com

Showing 10 out of 92 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-DNMT3B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: OVCAR-3 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: DNMT3B  Gene Name: Anonymous Submitted by: 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Dnmt3b Pab (ABIN387884) in T47-D cell lysate. Dnmt3b (arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC, ELISA, WB Western blot analysis of extracts from HT-29 cells, using DNMT3B Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using DNMT3B Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded: human colon cancer tissue labeled with Anti-Dnmt-3-beta Polyclonal Antibody, Unconjugated (ABIN727623) at 1:600, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded: rat spinal cord tissue labeled with Anti-Dnmt-3-beta Polyclonal Antibody (ABIN727623), Unconjugated at 1:600, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$315.00
Details
Human Mouse Un-conjugated ChIP, WB DNMT3B mAb tested by Western blot. Detection of DNMT3B by Western blot. The analysis was performed using DNMT3B mAb at a 2 µg/ml dilution and whole-cell extracts from 293 cells that had been transfected with plasmid expressing either mouse DNMT3A (lane A) or DNMT3B (lane B). 100 μg Log in to see 1 to 2 Days
$466.67
Details
Mouse Mouse Un-conjugated ChIP, ICC, IHC (p), IP, WB 100 μg Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA, WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated EIA, IF, IHC (p), WB Immunofluorescence analysis of HeLa cells, using DNMT3B Antibody. The picture on the right is treated with the synthesized peptide. Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 6 to 8 Days
$500.50
Details

DNMT3B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DNMT3B Antibodies

  1. Human Polyclonal DNMT3B Primary Antibody for IHC (p), WB - ABIN387884 : Lu, Markowetz, Unwin, Leek, Airoldi, MacArthur, Lachmann, Rozov, Maayan, Boyer, Troyanskaya, Whetton, Lemischka: Systems-level dynamic analyses of fate change in murine embryonic stem cells. in Nature 2009 (PubMed)
    Show all 13 references for ABIN387884

  2. Human Monoclonal DNMT3B Primary Antibody for ChIP, WB - ABIN2668954 : Castro, Breiling, Luetkenhaus, Ceteci, Hausmann, Kress, Lyko, Rudel, Rapp: MYC-induced epigenetic activation of GATA4 in lung adenocarcinoma. in Molecular cancer research : MCR 2013 (PubMed)
    Show all 2 references for ABIN2668954

  3. Chicken Polyclonal DNMT3B Primary Antibody for WB - ABIN2783648 : Boland, Christman: Characterization of Dnmt3b:thymine-DNA glycosylase interaction and stimulation of thymine glycosylase-mediated repair by DNA methyltransferase(s) and RNA. in Journal of molecular biology 2008 (PubMed)

  4. Human Polyclonal DNMT3B Primary Antibody for IF (p), IHC (p) - ABIN727623 : Zhao, Hou, Chen, Shao, Zhu, Bu, Gu, Li, Zhang, Du, Fu, Kong, Luo, Long, Li, Deng, Zhao, Cen: Prenatal cocaine exposure impairs cognitive function of progeny via insulin growth factor II epigenetic regulation. in Neurobiology of disease 2015 (PubMed)

  5. Human Polyclonal DNMT3B Primary Antibody for IF, IHC - ABIN1534163 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  6. Human Polyclonal DNMT3B Primary Antibody for EIA, IHC (p) - ABIN356569 : Stipani, Cappello, Daddabbo, Natuzzi, Miniero, Stipani, Palmieri: The mitochondrial oxoglutarate carrier: cysteine-scanning mutagenesis of transmembrane domain IV and sensitivity of Cys mutants to sulfhydryl reagents. in Biochemistry 2001 (PubMed)

More Antibodies against DNMT3B Interaction Partners

Zebrafish DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. dnmt7 specifically methylates no tail gene in the genome

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation (show HELLS Antibodies) content are rather a function of time, and not a genetic component.

Human DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Downregulation of DNMT3B, one of the targets identified using this method, radiosensitizes cancer cells by disturbing multiple DNA damage responses.

  2. The HBVX gene upregulated the mRNA and protein expression levels of DNMT3A (show DNMT3A Antibodies)/3B, downregulated the expression of SOCS1 (show SOCS1 Antibodies) and increased SOCS1 (show SOCS1 Antibodies) gene promoter CpG island methylation.

  3. Our results demonstrate DNMT3B4-del as a critical factor in developing aberrant DNA methylation (show HELLS Antibodies) patterns during lung tumorigenesis and suggest that DNMT3B4-del may be a target for lung cancer prevention.

  4. Results suggested that the DNMT3B -149C/T polymorphism is associated with a genetic susceptibility for developing LSCC in a Chinese population.

  5. Data indicate an epigenetic prognostic signature in glioblastomas based on expression of polycomb (show CBX2 Antibodies) repressive complex 2 (EZH2 (show EZH2 Antibodies)), DNA-methyltransferases DNMT1 (show DNMT1 Antibodies) and 3B which can be used easily in routine neuropathology practice.

  6. miR (show MLXIP Antibodies)-124 and miR (show MLXIP Antibodies)-506 inhibit progression and increase sensitivity to chemotherapy by targeting DNMT3B and DNMT1 (show DNMT1 Antibodies) in colorectal carcinoma.

  7. Increasing DNA methylation (show HELLS Antibodies) in the gene-coding area of DNMT3B was associated with higher risk of colorectal adenomas (OR = 1.34; 95% CI: 1.01-1.79 per SD).

  8. To correlate DNMTs expression with DNA methylation (show HELLS Antibodies), DNMT1 (show DNMT1 Antibodies), DNMT3A (show DNMT3A Antibodies) and DNMT3B mRNA levels in 5 colorectal cancer cell lines; results suggest that cellular DNMT (show DNMT1 Antibodies) expression is positively correlated with global DNA methylation (show HELLS Antibodies) level but not with regional DNA hypermethylation at each locus.

  9. Deregulated Dnmt3b targets have prognostic impact in acute myeloid leukemia patients.

  10. DNMT1 (show DNMT1 Antibodies), DNMT3B, and EZH2 (show EZH2 Antibodies) were expressed at significantly higher levels in tumor vs. normal tissues.

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. The epiblast expressed epithelial markers, MUC1 (show MUC1 Antibodies) and E-CADHERIN (show CDH1 Antibodies), and the pluripotency markers, DNMT3B and CRIPTO (show TDGF1 Antibodies).

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.

  2. The expression levels of DNMT3a (show DNMT3A Antibodies) and DNMT3b were associated with several beef quality traits.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) interaction partners

  1. Downregulation of DNMT3B, one of the targets identified using this method, radiosensitizes cancer cells by disturbing multiple DNA damage responses.

  2. High levels of Dnmt3b expression prolong leukemia latency.

  3. The expression of DNMT1 (show DNMT1 Antibodies) and DNMT3b was decreased at 1 mT, and 50 Hz ELF (show SPTBN1 Antibodies)-EMF can increase the expression...the alterations of genome-wide methylation and DNMTs expression may play an important role in the biological effects of 50 Hz ELF (show SPTBN1 Antibodies)-EMF exposure

  4. DKO cardiomyocytes showed virtual absence of targeted Dnmt3a (show DNMT3A Antibodies) and Dnmt3b mRNA transcripts.

  5. An unexpected oncogenic role for Dnmt3a (show DNMT3A Antibodies) in MTCL through methylation-independent repression of Dnmt3b.

  6. we report that cardiac specific deletion of Dnmt3b, the predominant DNA methyltransferase (show DNMT1 Antibodies) in adult mouse hearts, leads to an accelerated progression to severe systolic insufficiency and myocardial thinning without a preceding hypertrophic response.

  7. These results indicated a role for the miR29b-Dnmt3a (show DNMT3A Antibodies)/3b-DNA methylation (show HELLS Antibodies) axis in mouse early embryonic development, and we provide evidence that miR29b is indispensable for mouse early embryonic development

  8. data suggest that Dnmt3a (show DNMT3A Antibodies) and Dnmt3b are critical to regulate the onset of Igkappa light chain rearrangement during early B-cell development

  9. Study reveals that the DNMT3 de novo methyltransferases DNMT3A (show DNMT3A Antibodies) and DNMT3B play both redundant and specific functions in the establishment of DNA methylation (show HELLS Antibodies) in the mouse embryo.

  10. Dnmt3b-deficient cells can contribute to the male and female germ-lines in chimeric mice and can produce normal progeny, establishing that Dnmt3b is dispensable for mouse gametogenesis and imprinting.

DNMT3B Antigen Profile

Protein Summary

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Gene names and symbols associated with DNMT3B

  • DNA (cytosine-5-)-methyltransferase 4 (dnmt4) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (DNMT3B) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (LOC100218113) antibody
  • DNA methyltransferase 3B (dnmt3b) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (dnmt3b) antibody
  • DNA (cytosine-5-)-methyltransferase 3 beta (Dnmt3b) antibody
  • DNA methyltransferase 3B (Dnmt3b) antibody
  • cb91 antibody
  • cb633 antibody
  • DNMT3B antibody
  • dnmt3bl antibody
  • dnmt7 antibody
  • ICF antibody
  • ICF1 antibody
  • LOC100218113 antibody
  • M.HsaIIIB antibody
  • MmuIIIB antibody
  • sb:cb91 antibody
  • wu:fb16h07 antibody

Protein level used designations for DNMT3B

DNA (cytosine-5)-methyltransferase 3B , DNA (cytosine-5-)-methyltransferase 3 beta , DNA cytosine-5 methyltransferase 3 beta , DNA (cytosine-5)-methyltransferase 3B-like , DNA methyl transferase beta , DNA methyltransferase 3B , DNA MTase HsaIIIB , DNA methyltransferase HsaIIIB , DNA (cytosine-5-)-methyltransferase 3 beta, like , DNA (cytosine-5-)-methyltransferase 7 , fb16h07 , DNA MTase MmuIIIB , DNA methyltransferase MmuIIIB

GENE ID SPECIES
317744 Danio rerio
458174 Pan troglodytes
711553 Macaca mulatta
100053900 Equus caballus
100218113 Taeniopygia guttata
100412936 Callithrix jacchus
100459992 Pongo abelii
100466728 Ailuropoda melanoleuca
100500777 Ovis aries
100598378 Nomascus leucogenys
100528060 Anolis carolinensis
1789 Homo sapiens
321084 Danio rerio
419287 Gallus gallus
100302109 Sus scrofa
353354 Bos taurus
444985 Rattus norvegicus
13436 Mus musculus
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