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DNA-Damage-Inducible Transcript 4-Like Proteins (DDIT4L)

Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.. Additionally we are shipping DDIT4L Antibodies (59) and DDIT4L Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DDIT4L 115265 Q96D03
DDIT4L 73284 Q8VHZ5
DDIT4L 140582 Q8VD50
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Top DDIT4L Proteins at antibodies-online.com

Showing 7 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,464.00
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,464.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,464.00
Details
Yeast Oncorhynchus mykiss His tag   1 mg Log in to see 56 to 66 Days
$2,504.33
Details

DDIT4L Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for DNA-Damage-Inducible Transcript 4-Like (DDIT4L) Interaction Partners

Human DNA-Damage-Inducible Transcript 4-Like (DDIT4L) interaction partners

  1. RTP801 (show DDIT4 Proteins) and RTP801L work downstream of AKT (show AKT1 Proteins) and upstream of TSC2 to inhibit mTOR (show FRAP1 Proteins) functions

  2. mediates monocyte cell death through a reduction in thioredoxin-1 expression

  3. Promoter methylation and differential gene expression of five markers: COL1A2, NPM2, HSPB6, DDIT4L and MT1G were validated by sequencing of bisulfite-modified DNA and real-time reverse transcriptase PCR, respectively.

Mouse (Murine) DNA-Damage-Inducible Transcript 4-Like (DDIT4L) interaction partners

  1. Axonal injury-induced upregulation of the stress-responsive REDD2 leads to mTOR (show FRAP1 Proteins) inhibition triggering early dendritic arbor retraction, neuronal dysfunction and subsequent death of adult retinal neurons.

  2. IRF-1 (show IRF1 Proteins) physically interacts with REDD2 in the large cytoplasmic protein (show BLZF1 Proteins) complex

  3. SMHS1 was found to be expressed in skeletal muscle, and comparisons of its expression in atrophied versus hypertrophied muscles and in oxidative versus glycolytic muscles suggested that SMHS1 contributes to muscle energy metabolism phenotypes.

  4. RTP801 (show DDIT4 Proteins) and RTP801L work downstream of AKT (show AKT1 Proteins) and upstream of TSC2 to inhibit mTOR (show FRAP1 Proteins) functions

  5. REDD2 is enriched in skeletal muscle and inhibits mTOR (show FRAP1 Proteins) signaling in response to leucine and stretch.

DDIT4L Protein Profile

Protein Summary

Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.

Gene names and symbols associated with DDIT4L

  • DNA-damage-inducible transcript 4-like (DDIT4L)
  • DNA-damage-inducible transcript 4-like (ddit4l)
  • DNA-damage-inducible transcript 4-like (Ddit4l)
  • 1700037B15Rik protein
  • 1700108M02Rik protein
  • REDD2 protein
  • RTP801L protein
  • Smhs1 protein

Protein level used designations for DDIT4L

DNA damage-inducible transcript 4-like protein , DNA-damage-inducible transcript 4-like , HIF-1 responsive protein RTP801-like , REDD-2 , homolog of mouse SMHS1 , protein regulated in development and DNA damage response 2 , regulated in development and DNA damage response 2 , DNA-damage-inducible transcript 4-like protein , skeletal muscle hindlimb suspension 1 , soleus muscle atrophied after hindlimb suspension protein 1

GENE ID SPECIES
709499 Macaca mulatta
461401 Pan troglodytes
100194546 Salmo salar
115265 Homo sapiens
487877 Canis lupus familiaris
510906 Bos taurus
73284 Mus musculus
140582 Rattus norvegicus
100136335 Oncorhynchus mykiss
100173061 Pongo abelii
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