You are viewing an incomplete version of our website. Please click to reload the website as full version.

Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Proteins (DACT2)

Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors (By similarity).. Additionally we are shipping Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Antibodies (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DACT2 240025 Q7TN08
DACT2 168002 Q5SW24
Rat DACT2 DACT2 308212  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

DACT2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) Interaction Partners

Mouse (Murine) Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) interaction partners

  1. we have identified a novel role for Dact2 as an inhibitor of the canonical Wnt (show WNT2 Proteins) pathway in embryonic tooth development through its regulation of cell proliferation and differentiation.

  2. conserved role for Dact2 protein in kinase-regulated biochemistry involving Vangl and Dvl (show DVL1 Proteins).

  3. Dact2 plays a role in regulating morphogenesis by renal collecting duct cells, probably by protecting cells from overly strong TGF-beta (show TGFB1 Proteins) pathway activation.

  4. Dact2 may play important signal-modulating roles in the adjacent epithelial cells including the enamel knot signaling centers and pre-ameloblasts.

  5. Dact2 expression is most prominent during organogenesis of the thymus, kidneys, and salivary glands, with much lower levels in the somites and in the developing CNS.

  6. Dpr2 plays an inhibitory role in the re-epithelialization of adult skin wounds by attenuating TGFbeta (show TGFB1 Proteins) signaling.

Human Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) interaction partners

  1. This study demonstrated that Genes overexpressed in Pilomyxoid Astrocytoma vs. Pilocytic Astrocytoma, ranked according to fold-change, included developmental genes H19 (show NCKAP1 Proteins), DACT2,COL2A1 (show COL2A1 Proteins); COL1A1 (show COL1A1 Proteins) and IMP3 (show IGF2BP3 Proteins).

  2. DACT2 suppresses papillary thyroid cancer proliferation and metastasis by inhibiting Wnt (show WNT2 Proteins) signaling.

  3. There was no statistical difference between groups concerning DACT1 (show DACT1 Proteins) and DACT2 either in promoter hypermethylation or transcript levels. Age was associated with DACT2 promoter hypermethylation, especially over 56 years old.

  4. DACT2 acts as a functional tumor suppressor in colon cancer through inhibiting Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling. Its methylation at early stages of colon carcinogenesis is an independent prognostic factor.

  5. DACT2 suppresses hepatocellular carcinoma by inhibiting Wnt (show WNT2 Proteins) signaling in human hepatocellular carcinoma cells.

  6. Loss of DACT2 expression is associated with esophageal squamous cell carcinoma.

  7. Reduced expression of DACT2 due to methylation-mediated gene silencing promotes hepatocellular carcinoma progression

  8. Epigenetic regulation of DACT2 is a key component of the Wnt (show WNT2 Proteins) signalling pathway in human lung cancer.

  9. Hypermethylation of Dact1 (show DACT1 Proteins) gene is associated with transitional cell carcinomas.

  10. Nuclear beta-catenin (show CTNNB1 Proteins) was more frequently expressed in non-polypoid growth low grade colorectal neoplasms than in polypoid growth neoplasms.

Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) (DACT2) Protein Profile

Protein Summary

Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors (By similarity).

Gene names and symbols associated with DACT2

  • dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis) (DACT2)
  • dapper homolog 2, antagonist of beta-catenin (xenopus) (Dact2)
  • dishevelled-binding antagonist of beta-catenin 2 (DACT2)
  • dishevelled-binding antagonist of beta-catenin 2 (Dact2)
  • 2900084M21Rik protein
  • A630024E20 protein
  • bA503C24.7 protein
  • C6orf116 protein
  • DAPPER2 protein
  • DPR2 protein
  • Frd2 protein
  • RP11-503C24.7 protein

Protein level used designations for DACT2

dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis) , dapper homolog 2-like , dapper antagonist of catenin 2 , dapper homolog 2 , dapper, antagonist of beta-catenin, homolog 2 , mDpr2 , dapper homolog 2, antagonist of beta-catenin

GENE ID SPECIES
742130 Pan troglodytes
100462224 Pongo abelii
240025 Mus musculus
421561 Gallus gallus
168002 Homo sapiens
308212 Rattus norvegicus
Selected quality suppliers for Dapper, Antagonist of beta-Catenin, Homolog 2 (Xenopus Laevis) Proteins (DACT2)
Did you look for something else?