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anti-Decorin (DCN) Antibodies

The protein encoded by DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. Additionally we are shipping Decorin Kits (61) and Decorin Proteins (28) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DCN 1634 P07585
DCN 13179 P28654
DCN 29139 Q01129
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Top anti-Decorin Antibodies at

Showing 10 out of 179 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-DCN Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of DCN antibody (Center) (ABIN390518) in mouse heart tissue lysates (35 µg/lane). DCN (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with DCN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
Cow Goat Un-conjugated WB AP26012PU-N (0.5µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
Human Mouse Un-conjugated FACS, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to DCN on formalin-fixed paraffin-embedded human adrenal gland (antibody concentration 3 µg/mL).  Detection limit for recombinant GST tagged DCN is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
Human Goat Un-conjugated ELISA, WB Western Blot: Decorin Antibody [NBP1-51962] - (0.5ug/ml) staining of Human Kidney lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 5 to 7 Days
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: Decorin Antibody [NBP1-57923] - Human skin tissue at an antibody concentration of 4-8ug/ml. Western Blot: Decorin Antibody [NBP1-57923] - Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta 100 μL Log in to see 6 to 9 Days

DCN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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, , , , , , ,
Mouse (Murine) , ,
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Rat (Rattus) , ,


Top referenced anti-Decorin Antibodies

  1. Human Monoclonal Decorin Primary Antibody for IHC (p), ELISA - ABIN396139 : Johnatty, Beesley, Chen, Macgregor, Duffy, Spurdle, deFazio, Gava, Webb, Rossing, Doherty, Goodman, Lurie, Thompson, Wilkens, Ness, Moysich, Chang-Claude, Wang-Gohrke, Cramer, Terry, Hankinson, Tworoger, Garcia-Closas, Yang, Lissowska, Chanock, Pharoah, S: Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot". in PLoS genetics 2010 (PubMed)
    Show all 5 references for ABIN396139

  2. Human Monoclonal Decorin Primary Antibody for FACS, ELISA - ABIN1724881 : Buraschi, Neill, Owens, Iniguez, Purkins, Vadigepalli, Evans, Schaefer, Peiper, Wang, Iozzo: Decorin protein core affects the global gene expression profile of the tumor microenvironment in a triple-negative orthotopic breast carcinoma xenograft model. in PLoS ONE 2012 (PubMed)
    Show all 2 references for ABIN1724881

  3. Human Polyclonal Decorin Primary Antibody for FACS, IHC (p) - ABIN390518 : Goldoni, Humphries, Nyström, Sattar, Owens, McQuillan, Ireton, Iozzo: Decorin is a novel antagonistic ligand of the Met receptor. in The Journal of cell biology 2009 (PubMed)
    Show all 2 references for ABIN390518

  4. Human Monoclonal Decorin Primary Antibody for ELISA, WB - ABIN1724878 : Adam, Saller, Ströbl, Hennebold, Dissen, Ojeda, Stouffer, Berg, Berg, Mayerhofer: Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule. in Human reproduction (Oxford, England) 2012 (PubMed)
    Show all 2 references for ABIN1724878

  5. Human Polyclonal Decorin Primary Antibody for ELISA, WB - ABIN4304717 : Zafiropoulos, Nikitovic, Katonis, Tsatsakis, Karamanos, Tzanakakis: Decorin-induced growth inhibition is overcome through protracted expression and activation of epidermal growth factor receptors in osteosarcoma cells. in Molecular cancer research : MCR 2008 (PubMed)

  6. Chicken Polyclonal Decorin Primary Antibody for IHC, WB - ABIN2783275 : Nakatani, Honda, Hayakawa, Sato, Satoh, Kudo, Munakata: Effects of decorin on the expression of alpha-smooth muscle actin in a human myofibroblast cell line. in Molecular and cellular biochemistry 2008 (PubMed)

More Antibodies against Decorin Interaction Partners

Human Decorin (DCN) interaction partners

  1. analysis of decorin and lumican (show LUM Antibodies) expression in fibroblasts correlated with palmoplantar collagen bundle size

  2. via gain-of-function analyses, DCN overexpression could inhibit renal cell carcinoma (show MOK Antibodies) (RCC (show XRCC1 Antibodies)) cell proliferation and metastasis in vitro and vivo. At the mechanism level, we found that an ectopic expression of DCN significantly upregulated P21 (show CDKN1A Antibodies) and E-cadherin (show CDH1 Antibodies) expression. Altogether, these results revealed that DCN is a tumor suppressor in RCC (show XRCC1 Antibodies), and it could serve as a potential therapeutic target in patients with RCC (show XRCC1 Antibodies).

  3. Internal mammary artery tissue from active smokers contains decreased amounts of type 1 collagen and decorin.

  4. A synthetic peptide corresponding to this decorin region dose-dependently inhibited the response to myostatin (show MSTN Antibodies) in cardiomyocytes

  5. increased blood DCN levels could be a candidate biomarker for PE.

  6. An emerging concept that multiple proteases, especially those produced by inflammatory cells, are capable of cleaving DCN suggests that native DCN could be inactivated in a number of pathological inflammatory conditions

  7. Decorin plays a key role in the maintenance of the order in the normal corneal extracellular matrix.

  8. Compared with bone graft and marrow cavity contents, sticking scars had the highest expression of BMP-2 (show BMP2 Antibodies) while bone grafts had the highest expression of DCN.

  9. Defective Proteolytic Processing of Fibrillar Procollagens and Prodecorin Due to Biallelic BMP1 (show BMP1 Antibodies) Mutations Results in a Severe, Progressive Form of Osteogenesis Imperfecta (show COL1A2 Antibodies).

  10. Data show that decorin is not only associated with angiogenesis, but it plays a causal role in this process. Also, depending on the molecular microenvironment where angiogenesis is induced, decorin can either promote or inhibit angiogenesis. [review]

Cow (Bovine) Decorin (DCN) interaction partners

  1. The inclusion of decorin proteoglycan during fibrillogenesis of type I collagen increases the modulus and tensile strength of resulting collagen gels.

  2. These findings reveal a novel role of DCN as an antagonistic ligand for VEGFR-2 (show KDR Antibodies).

  3. Data show that biglycan (show BGN Antibodies), collagen type I, collagen type II, decorin, and versican (show Vcan Antibodies) were significantly affected by vibration duration, frequency, and amplitude.

  4. Results suggest that decorin contributes to the formation and stabilization of collagen fibres in the perimysium that support muscle fibres assembled with myogenesis.

  5. decorin is a dimer in solution

  6. decorin-induced fibroblast cytoskeletal and signalling changes result in an increased cell migration; potential role in the remodelling process

  7. Transduced bovine decorin synthesized de novo by rat arterial smooth muscle cells increases type I collagen synthesis and enhances contraction of collagen gels.

  8. The results indicate that CTGF (show CTGF Antibodies) suppresses the synthesis of biglycan (show BGN Antibodies) but newly induced that of decorin in the cells when the cell density is low.

  9. a novel collagen binding domain in decorin acts cooperatively with leucine-rich repeat 4 to mask the alpha2beta1 integrin-binding site on collagen, an important sequence for the phagocytosis of collagen fibrils

  10. analysis of decorin from different bovine tissues

Mouse (Murine) Decorin (DCN) interaction partners

  1. A synthetic peptide corresponding to this decorin region dose-dependently inhibited the response to myostatin (show MSTN Antibodies) in cardiomyocytes

  2. Systemic delivery of an oncolytic adenovirus expressing decorin for the treatment of breast cancer bone metastases reduced tumor burden and inhibited bone destruction.

  3. Decorin is an autophagy-inducible proteoglycan (show Vcan Antibodies) and is required for proper in vivo autophagy.

  4. Importance of biglycan (show BGN Antibodies) and decorin as targets for the manipulation of fetal membrane extracellular matrix stability in the context of inflammation.

  5. The results suggest that decorin plays a dual role in AAA (show AAAS Antibodies). Adventitial decorin in normal aorta may protect against the development of AAA (show AAAS Antibodies)

  6. Development of congenital stromal dystrophy is dependent on export and extracellular deposition of truncated decorin.

  7. decorin may modulate follicular cycling and morphogenesis

  8. We found that decorin is abundantly secreted and deposited in normal connective tissue but its expression is consistently decreased in the tumor microenvironment.

  9. Decorin signaling supported fetal membrane remodeling at early stages of gestation in a TGFbeta (show TGFB1 Antibodies)-dependent manner, and fetal membrane stabilization at later stages of gestation without changes in TGFbeta (show TGFB1 Antibodies) levels.

  10. A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function.

Pig (Porcine) Decorin (DCN) interaction partners

  1. LDL electrostatic interactions with decorin and biglycan (show BGN Antibodies) in the aortic valve leaflets and vascular wall is a major source of LDL retention.

  2. The expression of the DCN gene increased from gestational day 26 to 90 in both Yorkshire and Meishan pig placenta.

Decorin (DCN) Antigen Profile

Protein Summary

The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome.

Gene names and symbols associated with anti-Decorin (DCN) Antibodies

  • decorin (DCN) antibody
  • decorin (Dcn) antibody
  • decorin (dcn) antibody
  • cscd antibody
  • DC antibody
  • DCN antibody
  • dspg2 antibody
  • mDcn antibody
  • pg40 antibody
  • pgii antibody
  • pgs2 antibody
  • slrr1b antibody

Protein level used designations for anti-Decorin (DCN) Antibodies

decorin , PG-S2 , bone proteoglycan II , decorin proteoglycan , dermatan sulphate proteoglycans II , proteoglycan core protein , small leucine-rich protein 1B , DSPG , PG40 , dermatan sulfate proteoglycan-II (decorin) , DS-PGII , dermatan sulfate proteoglycan II

100033862 Equus caballus
417892 Gallus gallus
1634 Homo sapiens
280760 Bos taurus
13179 Mus musculus
396957 Sus scrofa
100009171 Oryctolagus cuniculus
29139 Rattus norvegicus
403904 Canis lupus familiaris
447482 Xenopus laevis
100174912 Cavia porcellus
100034120 Equus caballus
443048 Ovis aries
100860944 Capra hircus
452120 Pan troglodytes
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