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Defensin, beta 1 Proteins (DEFB1)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping beta Defensin 1 Antibodies (171) and beta Defensin 1 Kits (36) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DEFB1 13214 P56386
DEFB1 83687 O89117
DEFB1 1672 P60022
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Top beta Defensin 1 Proteins at

Showing 10 out of 48 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 11 to 13 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Wild boar His tag   1 mg Log in to see 56 to 66 Days
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
Yeast Chinchilla lanigera His tag   1 mg Log in to see 56 to 66 Days
HOST_Escherichia coli (E. coli) Rat Un-conjugated   20 μg Log in to see 15 to 19 Days
HOST_Escherichia coli (E. coli) Mouse His tag   100 μg Log in to see 11 to 13 Days

DEFB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human , , , ,
, , ,

More Proteins for Defensin, beta 1 (DEFB1) Interaction Partners

Cow (Bovine) Defensin, beta 1 (DEFB1) interaction partners

  1. Stimulation of umbilical-vein endothelial cells with S. aureus or LPS (show IRF6 Proteins) induced the expression of bovine beta-defensin 1. This expression was regulated by the autocrine production of tumor necrosis factor-alpha (show TNF Proteins).

  2. The synthetic peptides bovine enteric beta-defensin (EBD), bovine neutrophil beta-defensin (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.(

Mouse (Murine) Defensin, beta 1 (DEFB1) interaction partners

  1. Fenofibrate and gemfibrozil inhibit LPS (show TLR4 Proteins)-induced inflammatory activation of macrophages via PPARalpha (show PPARA Proteins)/beta-defensin 1/TLR4 (show TLR4 Proteins) pathway.

  2. these studies demonstrate a role for the murine beta-defensin 1 peptide in early control of Candida infection in a murine model of mucosal candidiasis

  3. Akt1 (show AKT1 Proteins) is involved in the regulation of defensin (show DEF Proteins) expression and the innate immune response important for bacterial clearance

  4. Histopathology showed a greater inflammatory influx in the lungs of mBD-1((-/-)) mice at Day 3 postinfection compared with WT C57BL/6 mice

  5. The decreased production of antimicrobial peptides by burn-site epidermal keratinocytes influenced by Gr-1 (show GSR Proteins)(+)CD11b (show ITGAM Proteins)(+) cells was shown to be restored by glycyrrhizin.

  6. elimination of mBD-1 results in a defect in the ability of the host to clear H. influenzae from the lung, which is most consistent with this peptide functioning as an antibiotic at the airway surface.

  7. The expression of BD1 was significantly elevated in the lungs of cigarette smoke-exposed mice compared with air-exposed mice.

  8. Although both murine beta-defensin (mBD)-1 and mBD2 are constitutively expressed in normal BALB/c and C57BL/6 corneas, mBD-1 is not required for host resistance against Pseudomonas aeruginosa-induced corneal infection.

Human Defensin, beta 1 (DEFB1) interaction partners

  1. DEFB1 polymorphisms alone may not influence pathology susceptibility, however they could possibly concur, together with other factors involved in the genetic control of innate immune system, in the predisposition towards recurrent tonsillitis

  2. beta-defensin-1 production is dysregulated in the epithelium of patients with chronic obstructive pulmonary disease

  3. dental plaque amount, lactobacilli count, age, and saliva (show RAG1AP1 Proteins) buffer capacity, as well as DEFB1 gene polymorphism, explained a total of 87.8% of variations in DMFT scores.

  4. Our meta-analysis provides evidence that DEFB1 genetic polymorphisms rs11362G>A, rs1800972C>G and rs1799946G>A are important contributing factors to the development of digestive diseases

  5. Association of infectious pathology of upper respiratory tract and development of periodontitis diseases with markers in DEFB1 (-44G/C) and TLR2 Arg753Gln and Arg677Trp genes was determined.

  6. Genotypes and alleles of the DEFB1 gene found in long-living individuals can be considered as the factors that increase the probability of longevity and favorable course of age-related diseases.

  7. Possible association between DEFB1 polymorphisms and in vivo salivary levels of hBD-1 in an Italian population of 40 healthy individuals, finding a genotype-related different expression with two of these polymorphisms: -52G > A and -44C > G.

  8. We found that RNA interference-induced Caspase-12 silencing increased NOD1 (show NOD1 Proteins), hBD1 and hBD2 (show DEFB4 Proteins) expression

  9. A-dependent DEFB1 upregulation below 20 mM predicts in vitro antimicrobial activity as well as glucose- and AA-dependent CAMP and IFNG (show IFNG Proteins) upregulation.

  10. The DEFB1 c.-44C>G polymorphism of the GG protective genotype was much less frequent among multiple sclerosis patients than among the controls.

Pig (Porcine) Defensin, beta 1 (DEFB1) interaction partners

  1. pBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide.

  2. Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line.

  3. Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets

beta Defensin 1 (DEFB1) Protein Profile

Protein Summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

Gene names and symbols associated with Defensin, beta 1 Proteins (DEFB1)

  • defensin, beta 1 (DEFB1)
  • beta defensin (LOC100296173)
  • beta-defensin-1 (BD-1)
  • defensin beta 1 (Defb1)
  • gallinacin 1 (GAL1)
  • AW260221 protein
  • BD-1 protein
  • BD1 protein
  • CBD1 protein
  • DEFB-1 protein
  • DEFB1 protein
  • DEFB1-like protein
  • DEFB101 protein
  • EBD protein
  • GAL3 protein
  • HBD1 protein
  • PBD-1 protein
  • RHBD-1 protein

Protein level used designations for Defensin, beta 1 Proteins (DEFB1)

Gal 3 , antimicrobial peptide-3 , beta-defensin 1 , beta-defensin 3 , beta-defensin prepropeptide , gal-3 , gallinacin-3 , Beta-defensin 1 , Defensin, beta 1 , BD-1 , rBD-1 , beta-defensin-1 , prepro-beta-defensin 1 , defensin, beta 1 (enteric) , enteric beta-defensin , enteric prepro-beta-defensin , beta defensin-1 homolog , cBD1 , Gal 1 , Gal 1-alpha , antimicrobial peptide 1 , antimicrobial peptide CHP2 , chicken heterophil peptide 2 , gal-1 alpha , gallinacin-1 alpha

395363 Gallus gallus
611241 Canis lupus familiaris
100296173 Bos taurus
100861170 Capra hircus
13214 Mus musculus
83687 Rattus norvegicus
1672 Homo sapiens
396819 Sus scrofa
281743 Bos taurus
574187 Macaca mulatta
450100 Pan troglodytes
395841 Gallus gallus
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