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Defensin, beta 4A Proteins (DEFB4)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping Defensin, beta 4A Antibodies (123) and Defensin, beta 4A Kits (57) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DEFB4 13215 P82020
DEFB4 641631  
DEFB4 1673 O15263
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Top Defensin, beta 4A Proteins at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag,S tag 100 μg Log in to see 11 to 13 Days
$683.10
Details
HOST_Escherichia coli (E. coli) Rat His tag,GST tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$3,701.25
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$528.00
Details
Yeast Pan troglodytes His tag   1 mg Log in to see 56 to 66 Days
$1,991.00
Details
Yeast Macaca mulatta His tag   1 mg Log in to see 56 to 66 Days
$1,991.00
Details
Yeast Sheep His tag   1 mg Log in to see 56 to 66 Days
$1,994.67
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   0.005 mg Log in to see 2 to 3 Days
$178.75
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   20 μg Log in to see 15 to 19 Days
$314.16
Details

DEFB4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Rat (Rattus)

Human ,

More Proteins for Defensin, beta 4A (DEFB4) Interaction Partners

Pig (Porcine) Defensin, beta 4A (DEFB4) interaction partners

  1. The results demonstrate that transgenic overexpression of PBD-2 in pigs confers enhanced resistance against Actinobacillus pleuropneumoniae infection.

  2. Zinc sulfate and L-isoleucine induce beta defensin (show DEFB1 Proteins) expression in a porcine cell line.

  3. pBD-2 may be an important defense molecule for intestinal health.

Turkey Defensin, beta 4A (DEFB4) interaction partners

Mouse (Murine) Defensin, beta 4A (DEFB4) interaction partners

  1. NOD2-mediated beta-defensin 2 regulation contributes to the protection against NTHi-induced otitis media

  2. mouse urothelium produces mBD2 in response to intravesicular BCG (show SLC11A1 Proteins) as a defense mechanism against BCG (show SLC11A1 Proteins)

  3. visfatin (show NAMPT Proteins) enhances CAMP, hBD-2, hBD-3 (show DEFB103A Proteins), and S100A7 (show S100A7 Proteins) production in human keratinocytes and their orthologs in murine imiquimod-treated psoriatic skin.

  4. studied the time course of TLR9 (show TLR9 Proteins) and BD-2gene expression by the corneal epithelial cells in herpetic keratitis in C57Bl/6 and BALB/c mice

  5. mBD-2 was located in cells with dendritic morphology near mediastinal lymph nodes. mBD-2 may play a role in the control of bacilli growth by contributing to establish a Th1 (show HAND1 Proteins) response, being a link between innate and adaptative immunity.

  6. a highly size-specific, TLR4 (show TLR4 Proteins)-dependent, innate defense response to fragmented HA contributes to intestinal epithelium barrier defense through the induction of intracellular HbetaD2 protein.

  7. Murine beta-defensins BD2 and BD3 (show DEFB103A Proteins) together promote resistance against corneal infection by Pseudomonas aeruginosa.

  8. acts directly on immature dendritic cells as an endogenous ligand for Toll-like receptor 4 (show TLR4 Proteins), inducing up-regulation of costimulatory molecules and dendritic cell maturation

  9. The results indicate that BD-2 and -3 may be upregulated during the development of autoimmune sialoadenitis.

  10. Murine beta-defensin 2 (mDF2beta) can act as an endogenous ligand for TLR-4 (show TLR4 Proteins)-activating maturation of dendritic cells.

Human Defensin, beta 4A (DEFB4) interaction partners

  1. EMMPRIN, MMP8 (show MMP8 Proteins), hyaluronan, beta-defensing-2, and neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 Proteins)) are elevated in women with vaginal inflammation

  2. The copy numbers of DEFB4 gene may be associated with ankylosing spondylitis and involved in disease progression.

  3. Study found that HBD2 bound tightly to Mc1r (show MSHR Proteins) with an affinity similar to that of HBD3 (show DEFB103A Proteins)

  4. human lung epithelial cells secrete CCL20 (show CCL20 Proteins) and BD2 in response to B (show TDO2 Proteins). abortus and/or to cytokines produced by infected monocytes.

  5. Methylglyoxal and glyoxal in vitro irreversibly adduct to the recombinant human BD-2 peptide, and significantly reduce antimicrobial and chemotactic functions.

  6. HBD2 or HBD3 (show DEFB103A Proteins) cointernalized with virions in endosomes, formed oligomers, and reduced infectivity of human immunodeficiency virus.

  7. In periodontitis, TLR2 gene hyperexpression was accompanied by the reduction of expression of anti-microbial peptide HBD-2, as well as in an increase of production of TNF-alpha (show TNF Proteins) and TGF-beta (show TGFB1 Proteins) by epithelial cells of periodontium mucosa.

  8. Unlike classical gating modifiers of toxin peptides from animal venoms, which generally bind to the Kv channel S3-S4 linker, hBD2 only targets residues in both the N and C termini of the S1-S2 linker to influence channel gating

  9. We found that RNA interference-induced Caspase-12 silencing increased NOD1 (show NOD1 Proteins), hBD1 (show DEFB1 Proteins) and hBD2 expression

  10. Results suggest that SIRT1 (show SIRT1 Proteins) mediates the induction of hBD2 and IL-8 (show IL8 Proteins) gene expression levels in A549 cell by S. pneumoniae. SIRT1 (show SIRT1 Proteins) may play a key role in host immune and defense response in A549.

Cow (Bovine) Defensin, beta 4A (DEFB4) interaction partners

  1. The synthetic peptides bovine enteric beta-defensin (EBD (show DEFB1 Proteins)), bovine neutrophil beta-defensin (show DEFB1 Proteins) (BNBD) 9 and BNBD 3 are chemotactic for immature dendritic cells.

Defensin, beta 4A (DEFB4) Protein Profile

Protein Summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.

Gene names and symbols associated with Defensin, beta 4A Proteins (DEFB4)

  • beta-defensin 2 (PBD-2)
  • Gal 4 (GAL4)
  • beta-defensin 2 (THP2)
  • defensin, beta 104 (DEFB104)
  • defensin, beta 4A (DEFB4A)
  • defensin beta 4 (defb4)
  • beta defensin 2 (SBD2)
  • defensin beta 2 (Defb2)
  • neutrophil beta-defensin-9 like peptide (BNBD-9-LIKE)
  • BD-2 protein
  • BD2 protein
  • BNBD-2 protein
  • BNDB-2 protein
  • DEFB-2 protein
  • DEFB2 protein
  • DEFB4 protein
  • DEFB4P protein
  • DEFB102 protein
  • DEFB104 protein
  • DEFB104B protein
  • HBD-2 protein
  • SAP1 protein
  • THP2 protein

Protein level used designations for Defensin, beta 4A Proteins (DEFB4)

beta-defensin 4 , gal-4 , gal-7 , gallinacin 7 , gallinacin-4 , gallinacin-7 , beta-defensin 2 , heterophil prepropeptide 2 , beta-defensin 104A , BD-4 , cBD-4 , DEFB-4 , beta-defensin 104 , beta-defensin 104B , defensin, beta 104 , defensin, beta 104A , beta-defensin 102 , defensin, beta 102 , defensin, beta 4 , beta-defensin 4A , defensin, beta 2 , skin-antimicrobial peptide 1 , BD-2 , rhBD-2 , beta-defensin 4, pseudogene , beta-defensin-2 , defensin, beta 4, pseudogene , Beta-defensin 2

GENE ID SPECIES
404699 Sus scrofa
414342 Gallus gallus
678665 Meleagris gallopavo
735929 Pan troglodytes
100135059 Canis lupus familiaris
100499592 Oncorhynchus mykiss
100505451 Ovis aries
13215 Mus musculus
641631 Rattus norvegicus
1673 Homo sapiens
574144 Macaca mulatta
450193 Pan troglodytes
404063 Bos taurus
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