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Defensin beta 4 Proteins (DEFB4)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Additionally we are shipping Defensin beta 4 Antibodies (28) and Defensin beta 4 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Mouse DEFB4 DEFB4 56519 P82019
DEFB4 64389 O88514
DEFB4 503618 Q8WTQ1
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Top Defensin beta 4 Proteins at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 2 to 3 Days
$3,071.25
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   20 μg Log in to see 7 to 9 Days
$328.21
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$1,991.00
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$1,991.00
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   20 μg Log in to see 15 to 19 Days
$314.16
Details
HOST_Escherichia coli (E. coli) Human His tag   1 mg Log in to see 3 to 4 Days
$3,035.21
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   1 mg Log in to see 9 to 12 Days
$2,640.00
Details
HOST_Escherichia coli (E. coli) Rat Un-conjugated   1 mg Log in to see 3 to 4 Days
$2,348.50
Details
HOST_Synthetic Human Un-conjugated   100 μg Log in to see 9 to 11 Days
$915.20
Details

DEFB4 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus) ,

Human , ,
,

More Proteins for Defensin beta 4 (DEFB4) Interaction Partners

Mouse (Murine) Defensin beta 4 (DEFB4) interaction partners

  1. this investigation revealed an indispensable role for BD3, BD4, and CRAMP in defense against F. solani-induced keratitis

  2. beta-defensin 4 and 14 contribute to the innate and adaptive immune response in their role as chemoattractants

  3. Data show that recombinant mBD4 (show MBD4 Proteins):Ig and hBD2:Ig fusion proteins retained potent antimicrobial activity against Gram-negative and Gram-positive bacteria, and that these fusion proteins showed specific binding to CCR6 (show CCR6 Proteins)-expressing cells.

  4. Mycobacterial infection induces the expression of mBD3 (show MBD3 Proteins) and mBD4 (show MBD4 Proteins), and both might participate in the control of mycobacterial growth.

Human Defensin beta 4 (DEFB4) interaction partners

  1. EMMPRIN, MMP8 (show MMP8 Proteins), hyaluronan, beta-defensing-2, and neutrophil gelatinase-associated lipocalin (NGAL (show LCN2 Proteins)) are elevated in women with vaginal inflammation

  2. The copy numbers of DEFB4 gene may be associated with ankylosing spondylitis and involved in disease progression.

  3. Study found that HBD2 bound tightly to Mc1r (show MSHR Proteins) with an affinity similar to that of HBD3 (show DEFB103A Proteins)

  4. human lung epithelial cells secrete CCL20 (show CCL20 Proteins) and BD2 in response to B (show TDO2 Proteins). abortus and/or to cytokines produced by infected monocytes.

  5. Methylglyoxal and glyoxal in vitro irreversibly adduct to the recombinant human BD-2 peptide, and significantly reduce antimicrobial and chemotactic functions.

  6. HBD2 or HBD3 (show DEFB103A Proteins) cointernalized with virions in endosomes, formed oligomers, and reduced infectivity of human immunodeficiency virus.

  7. In periodontitis, TLR2 gene hyperexpression was accompanied by the reduction of expression of anti-microbial peptide HBD-2, as well as in an increase of production of TNF-alpha (show TNF Proteins) and TGF-beta (show TGFB1 Proteins) by epithelial cells of periodontium mucosa.

  8. Unlike classical gating modifiers of toxin peptides from animal venoms, which generally bind to the Kv channel S3-S4 linker, hBD2 only targets residues in both the N and C termini of the S1-S2 linker to influence channel gating

  9. We found that RNA interference-induced Caspase-12 silencing increased NOD1 (show NOD1 Proteins), hBD1 (show DEFB1 Proteins) and hBD2 expression

  10. Results suggest that SIRT1 (show SIRT1 Proteins) mediates the induction of hBD2 and IL-8 (show IL8 Proteins) gene expression levels in A549 cell by S. pneumoniae. SIRT1 (show SIRT1 Proteins) may play a key role in host immune and defense response in A549.

Cow (Bovine) Defensin beta 4 (DEFB4) interaction partners

  1. Bovine DEFB4 mRNA is upregulated by lipopolysaccharide in bovine neutrophils and mammary epithelial cells and by 1,25-dihydroxyvitamin D3 in bovine monocytes and mammary epithelial cells.

  2. Recombinant mature bovine neutrophil beta-defensin 4 inhibits mycobacterial growth and controls intracellular survival of mycobacteria.

  3. Stimulation of umbilical-vein endothelial cells with S. aureus or LPS (show IRF6 Proteins) induced the expression of bovine neutrophil beta-defensin 4. This expression was regulated by the autocrine production of tumor necrosis factor-alpha (show TNF Proteins).

  4. The isolation of polymorphisms of BNBD-4 and milk production and somatic cell count are reported.

Defensin beta 4 (DEFB4) Protein Profile

Protein Summary

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 4, an antibiotic peptide which is locally regulated by inflammation.

Gene names and symbols associated with Defensin beta 4 Proteins (DEFB4)

  • defensin beta 4 (Defb4)
  • defensin, beta 104B (DEFB104B)
  • defensin, beta 4A (DEFB4A)
  • 2310001F05Rik protein
  • BD-2 protein
  • BD-4 protein
  • BNBD-4 protein
  • BNBD4 protein
  • DEFB-2 protein
  • DEFB-4 protein
  • DEFB2 protein
  • Defb3 protein
  • DEFB4 protein
  • DEFB102 protein
  • HBD-2 protein
  • hBD-4 protein
  • SAP1 protein

Protein level used designations for Defensin beta 4 Proteins (DEFB4)

beta-defensin 4 , BD-2 , BD-4 , RBD-2 , RBD-4 , beta defensin-2 , defensin beta 3 , beta-defensin 104 , defensin, beta 104 , beta-defensin 4A , defensin, beta 2 , defensin, beta 4 , skin-antimicrobial peptide 1 , BNDB-4 , neutrophil beta-defensin 4

GENE ID SPECIES
56519 Mus musculus
64389 Rattus norvegicus
503618 Homo sapiens
1673 Homo sapiens
286836 Bos taurus
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