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DCD encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. Additionally we are shipping Dermcidin Antibodies (59) and Dermcidin Proteins (8) and many more products for this protein.
Showing 3 out of 8 products:
Human DCD ELISA Kit for Sandwich ELISA - ABIN415209
Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014
Show all 2 references for ABIN415209
Reduced DCD concentration in sweat in patients with inflammatory acne may permit proliferation of P. acnes in pilosebaceous units, resulting in progression of inflammatory acne.
These findings imply that DCD promotes breast tumorigenesis via modulation of ERBB (show EGFR ELISA Kits) signaling pathways
Dermcidin binds platelets and may inhibit the therapeutic action of aspirin following acute myocardial infarction.
Data indicate that Y-P30 (show CENPV ELISA Kits)/dermcidin expressed in placentas of first trimester pregnancies.
Increased Dermcidin was also detected with immunoblotting.
major binding partners of LEKTI were found to be the antimicrobial peptide (show cAMP ELISA Kits) dermcidin and the serine protease (show F2 ELISA Kits) cathepsin G (show CTSG ELISA Kits) and no kallikreins.
Structure-activity analysis of the dermcidin-derived peptide DCD-1L, an anionic antimicrobial peptide (show cAMP ELISA Kits) present in human sweat.
revealed that Nck1 SH2 domain binds to the phosphotyrosine residue at position 20 (Y20) of the DCD
dermcidin was a novel platelet aggregating agent, and potentiated the ADP induced thrombosis in the animal model as well as acutely inhibited glucose induced insulin (show INS ELISA Kits) synthesis.
There was a significant correlation between weight loss and survival in the PIF (show PIF1 ELISA Kits)-positive non-small-cell lung cancer patients.
This gene encodes a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
, diffusible survival/evasion peptide
, proteolysis inducing factor
, survival promoting peptide