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anti-Desmin (DES) Antibodies

DES encodes a muscle-specific class III intermediate filament. Additionally we are shipping Desmin Kits (61) and Desmin Proteins (27) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DES 1674 P17661
DES 64362 P48675
DES 13346 P31001
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Top anti-Desmin Antibodies at antibodies-online.com

Showing 10 out of 322 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-Desmin Antibody (t16) (ABIN389226) in NCI-H460 cell line lysates (35 µg/lane).Desmin-pT16(arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-DES Antibody Titration: 5.0ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from HeLa/HepG2 cells, using Desmin (Ab-60) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Desmin (Ab-60) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN334386 (0.2µg/ml) staining of Human Skeletal Muscle lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Cow Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Mouse Un-conjugated IF, WB Western blot analysis of desmin. Mouse muscle lysate was probed with anti-desmin (clone RD301, ABIN967294) at concentrations 0.25 (lane 1), 0.125 (lane 2), and 0.06 µg/ml (lane 3). Desmin is identified as a band of ~53 kDa. 50 μg Log in to see 5 to 6 Days
$247.24
Details
Chicken Rabbit Un-conjugated IF (cc), IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat kidney tissue labeled with Anti-Desmin Polyclonal Antibody, Unconjugated (ABIN736566) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded mouse heart tissue labeled with Anti-Desmin Polyclonal Antibody, Unconjugated (ABIN736566) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details

DES Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Desmin Antibodies

  1. Chicken Monoclonal Desmin Primary Antibody for IF, WB - ABIN967294 : Broers, Carney, Klein Rot, Schaart, Lane, Vooijs, Ramaekers: Intermediate filament proteins in classic and variant types of small cell lung carcinoma cell lines: a biochemical and immunochemical analysis using a panel of monoclonal and polyclonal antibodies. in Journal of cell science 1987 (PubMed)
    Show all 4 references for ABIN967294

  2. Human Monoclonal Desmin Primary Antibody for IHC (p), WB - ABIN1106974 : Tidball: Desmin at myotendinous junctions. in Experimental cell research 1992 (PubMed)
    Show all 3 references for ABIN1106974

  3. Human Polyclonal Desmin Primary Antibody for EIA, WB - ABIN357901 : Li, Lilienbaum, Butler-Browne, Paulin: Human desmin-coding gene: complete nucleotide sequence, characterization and regulation of expression during myogenesis and development. in Gene 1989 (PubMed)
    Show all 2 references for ABIN357901

  4. Chicken Polyclonal Desmin Primary Antibody for IF (cc), IF (p) - ABIN736566 : Luo, Wu, Ye, Li, Hao, Kong, Zheng, Lin, Nie, Zhang: The transient expression of miR-203 and its inhibiting effects on skeletal muscle cell proliferation and differentiation. in Cell death & disease 2014 (PubMed)
    Show all 2 references for ABIN736566

  5. Cow (Bovine) Polyclonal Desmin Primary Antibody for WB - ABIN375065 : Chen, Chang, Trivedi, Capetanaki, Cryns: Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis. in The Journal of biological chemistry 2003 (PubMed)

  6. Chicken Polyclonal Desmin Primary Antibody for WB - ABIN2776843 : Pica, Kathirvel, Pramono, Lai, Yee: Characterization of a novel S13F desmin mutation associated with desmin myopathy and heart block in a Chinese family. in Neuromuscular disorders : NMD 2008 (PubMed)

  7. Human Polyclonal Desmin Primary Antibody for IHC (p), WB - ABIN389226 : Ariza, Coll, Fernández-Figueras, López, Mate, García, Fernández-Vasalo, Navas-Palacios: Desmin myopathy: a multisystem disorder involving skeletal, cardiac, and smooth muscle. in Human pathology 1995 (PubMed)

  8. Cow (Bovine) Polyclonal Desmin Primary Antibody for WB - ABIN2776842 : Fidziańska, Kotowicz, Sadowska, Goudeau, Walczak, Vicart, Hausmanowa-Petrusewicz: A novel desmin R355P mutation causes cardiac and skeletal myopathy. in Neuromuscular disorders : NMD 2005 (PubMed)

More Antibodies against Desmin Interaction Partners

Zebrafish Desmin (DES) interaction partners

  1. Desmin intermediate filaments are required for normal active force generation.

  2. Desmin distribution during muscle maturation changes from dispersed aggregates to a perinuclear concentration to striated (show NSDHL Antibodies) afterwards.

Human Desmin (DES) interaction partners

  1. Increasing desmin abnormalities were correlated with diastolic dysfunction progression.

  2. expression level of mutant versus wild-type desmin in mouse model as well as in skeletal muscle specimens derived from human R350P desminopathies; findings demonstrate missense-mutant desmin inflicts changes of the subcellular localization and turnover of desmin itself and of direct desmin-binding partners

  3. Results propose that the mutations affect desmin structure and cause its aberrant folding and subsequent aggregation, triggering disruption of myofibrils organization.

  4. identified disruption of the desmin system in gastrocnemius myofibers as an index of the myopathy and limitation of muscle function in patients with peripheral artery disease.

  5. The desmin intermediate filament network plays a major role in striated (show NSDHL Antibodies) muscle development and maintenance by integrating and coordinating most cellular components necessary for proper mechanochemical signaling, organelle cross-talk, energy production and trafficking processes required for proper tissue homeostasis. [Review]

  6. Data suggest that loss of the desmin-p. A120D filament localization at the intercalated disk indicates its clinical arrhythmogenic potential.

  7. we describe a new mutation located in the coiled 1B domain of desmin and associated with a predominant cardiac involvement and a high degree of cardiac sudden death in a large Indian pedigree with 12 affected members

  8. Perfomed proteomic analysis on a transgenic mouse model of severe cardiac hypertrophy; compared data to dataset of heart failure found MYH7 (show MYH7 Antibodies), IGFBP7 (show IGFBP7 Antibodies), ANXA2 (show ANXA2 Antibodies), and DESM to be biomarker candidates for heart failure.

  9. autosomal recessive mutations in DES cause LGMD2 (show CAPN3 Antibodies) phenotype without features of myofibrillar myopathy.

  10. Data suggest that for some filament-forming desmin mutants, the molecular etiology of desminopathy results from subtle deficiencies in their association with nebulin (show NEB Antibodies), a major actin-binding filament protein of striated (show NSDHL Antibodies) muscle.

Mouse (Murine) Desmin (DES) interaction partners

  1. E413K mutation induces desmin network disorganization, desmin aggregate formation and alters the traction forces generation of single myoblasts.

  2. This study identifies desmin as a new Asb2b target for proteasomal degradation in cardiomyocytes and suggests that accumulation of desmin could contribute to UPS impairment in Hypertrophic cardiomyopathy mice and patients

  3. found that inhibition of the Rac1 pathway (a G protein signaling pathway involved in diverse cellular processes), antioxidant treatment, and stimulation of macroautophagy reduced desmin aggregation by up to 75% in this model

  4. This demonstration of biomechanical integration by the desmin intermediate filament system suggests that it plays an active biological role in muscle in addition to its accepted structural role

  5. expression level of mutant versus wild-type desmin in mouse model as well as in skeletal muscle specimens derived from human R350P desminopathies; findings demonstrate missense-mutant desmin inflicts changes of the subcellular localization and turnover of desmin itself and of direct desmin-binding partners

  6. Disruption of both nesprin 1 (show SYNE1 Antibodies) and desmin results in decreased lifespan, body weight and muscle strength.

  7. The desmin intermediate filament network plays a major role in striated (show NSDHL Antibodies) muscle development and maintenance by integrating and coordinating most cellular components necessary for proper mechanochemical signaling, organelle cross-talk, energy production and trafficking processes required for proper tissue homeostasis. [Review]

  8. Desmin content and transversal stiffness of the left ventricle mouse cardiomyocytes and skeletal muscle fibers after a 30-day space flight on board "BION-M1" biosatellite

  9. the observed decline in [Ca(2 (show CA2 Antibodies)+)]mit was due to desmin aggregate accumulation resulting in the loss of desmin mitochondria interactions

  10. During fasting, desmin phosphorylation increases and enhances Trim32 (show TRIM32 Antibodies)-mediated degradation of the desmin cytoskeleton, which appears to facilitate the breakdown of Z-bands and thin filaments.

Cow (Bovine) Desmin (DES) interaction partners

  1. Results show that expression of desmin increased during the late fattening stage of of hanwoo steers and it contributes to the muscle contractile apparatus.

Desmin (DES) Antigen Profile

Protein Summary

This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.

Gene names and symbols associated with anti-Desmin (DES) Antibodies

  • desmin-like (LOC100059397) antibody
  • desmin (DES) antibody
  • desmin (des-b) antibody
  • desmin, gene 1 (des.1) antibody
  • desmin (des) antibody
  • desmin (LOC100220724) antibody
  • desmin-like (LOC100402007) antibody
  • desmin a (desma) antibody
  • desmin (Des) antibody
  • desmin b (desmb) antibody
  • desmin, gene 1 (des.1-a) antibody
  • desmin, gene 2 (des.2) antibody
  • cb290 antibody
  • cmd1i antibody
  • CSM1 antibody
  • CSM2 antibody
  • des antibody
  • des-a antibody
  • des-b antibody
  • desm antibody
  • desmin antibody
  • fb59a12 antibody
  • LGMD2R antibody
  • LOC100220724 antibody
  • MGC52614 antibody
  • MGC75911 antibody
  • MGC80853 antibody
  • wu:fb59a12 antibody
  • wu:fc11d08 antibody
  • zgc:109859 antibody
  • zgc:154009 antibody

Protein level used designations for anti-Desmin (DES) Antibodies

desmin , desmin, gene 1 , desmin-like , intermediate filament protein , muscle-specific intermediate filament desmin , fc11d08

GENE ID SPECIES
100059397 Equus caballus
100137488 Papio anubis
446868 Xenopus laevis
394739 Xenopus (Silurana) tropicalis
470657 Pan troglodytes
100136041 Oncorhynchus mykiss
100220724 Taeniopygia guttata
100402007 Callithrix jacchus
30148 Danio rerio
100586972 Nomascus leucogenys
395906 Gallus gallus
1674 Homo sapiens
64362 Rattus norvegicus
497091 Canis lupus familiaris
13346 Mus musculus
101097010 Felis catus
280765 Bos taurus
101117308 Ovis aries
100328890 Oryctolagus cuniculus
396725 Sus scrofa
100733478 Cavia porcellus
101837949 Mesocricetus auratus
768287 Danio rerio
379869 Xenopus laevis
733312 Xenopus laevis
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