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DPP6 encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. Additionally we are shipping DPP6 Kits (14) and DPP6 Proteins (12) and many more products for this protein.
Showing 10 out of 44 products:
Cow (Bovine) Polyclonal DPP6 Primary Antibody for WB - ABIN2782043
Uhl, Liu, Drgon, Johnson, Walther, Rose, David, Niaura, Lerman: Molecular genetics of successful smoking cessation: convergent genome-wide association study results. in Archives of general psychiatry 2008
This first familial case provides evidence for association between DPP6 haploinsufficiency and Gilles de la Tourette syndrome.
the cysteine-rich domain of DPP6 plays an important role in protein folding of DPP6 that is required for transport of DPP6/Kv4.2 (show KCND2 Antibodies) complexes out of the ER
DPP6 is critical for synaptic integration and excitation.
Two DPP6 de novo deletions and one missense mutation in familial microcephalic patients were identified.
WT PrP(C (show PRNP Antibodies)), in a DPP6-dependent manner, modulated Kv4.2 (show KCND2 Antibodies) channel properties, causing an increase in peak amplitude
Findings of this study indicate that an altered response of Kv4 (show KCNC1 Antibodies)/DPP6 to long-term neuroleptic administration is involved in neuroleptic-induced TD.
DPP6-mediated Purkinje fibers early-repolarization syndrome might be a novel molecular paradigm for some forms of idiopathic ventricular fibrillation.
Antibodies to DPPX are associated with a protracted encephalitis characterized by central nervous system hyperexcitability.
Results showed that DPP6, SPHKAP (show SPHKAP Antibodies) and ID4 (show ID4 Antibodies) were down regulated in acute myeloid leukemia (show BCL11A Antibodies) (AML (show RUNX1 Antibodies)) patients.
There was no evidence of association of dipeptidyl-peptidase 6 alleles with amyotrophic lateral sclerosis. Our negative results agree with those recently reported in additional Polish and Italian cohorts.
expression pattern of DPP6 suggests that it may be involved in mandible and tooth development.
Dipeptidyl-peptidase 6 has an unexpected but important role in cell adhesion and motility, impacting the hippocampal synaptic development and function.
DPP6 co-expression with TASK-3 (show KCNK9 Antibodies) results in the formation of a protein complex that enhances resting membrane potassium conductance.
the present study described epigenetic silencing of Dpp6 expression by DNA methylation (show HELLS Antibodies) and established that its ectopic expression can act as negative signal during RA induced neuronal differentiation of P19 (show CDKN2D Antibodies) cells.
In the presence of DPP6 or DPP10, cell surface Kv4.2 (show KCND2 Antibodies) protein expression is selectively increased.
The expression pattern of Dpp6 suggests that Dpp6 may be involved in embryonic craniofacial development.
The DPP6-E is selectively expressed in a few neuronal populations in brain including cerebellar granule neurons, hippocampal pyramidal cells and neurons in intermediary layers of the superior colliculus.
DPP6 is necessary and sufficient to explain the larger unitary conductance of neuronal Kv4 (show KCNC1 Antibodies) channels underlying the neuronal subthreshold-operating A-type potassium (K+) current.
This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
, DPP VI
, dipeptidyl aminopeptidase IV-related protein
, dipeptidyl aminopeptidase-like protein 6
, dipeptidyl aminopeptidase-related protein
, dipeptidyl peptidase 6
, dipeptidyl peptidase IV-like protein
, dipeptidyl peptidase IV-related protein
, dipeptidyl peptidase VI
, dipeptidylpeptidase 6
, dipeptidylpeptidase VI
, inversion, Chr 5, Harwell 6, proximal