DPP6 antibody (Middle Region)

Catalog No. ABIN2782044

This Rabbit Polyclonal antibody specifically detects DPP6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Rabbit, Cow, Horse, Guinea Pig, Dog, Zebrafish (Danio rerio) and Pig.

Quick Overview for DPP6 antibody (Middle Region) (ABIN2782044)

Target: DPP6 (Dipeptidyl-Peptidase 6 (DPP6))

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Horse, Guinea Pig, Dog, Zebrafish (Danio rerio), Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DPP6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DPP6 Antibody

Binding Specificity: Middle Region

Purpose: DPP6 Antibody - middle region

Sequence: FLIIHPTADE KIHFQHTAEL ITQLIRGKAN YSLQIYPDES HYFTSSSLKQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against DPP6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DPP6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44868-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for DPP6

Target: DPP6 (Dipeptidyl-Peptidase 6 (DPP6))

Alternative Name: DPP6

Background:

Background Information: DPP6 is a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties.This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: Dipeptidyl-peptidase 6

Alternative Symbols: VF2, DPL1, DPPX, MRD33

Protein Name: Dipeptidyl aminopeptidase-like protein 6

Molecular Weight: 91kDa

Gene ID: 1804

NCBI Accession: NP_001034439

UniProt: P42658