You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) Antibodies

DAB2 encodes a mitogen-responsive phosphoprotein. Additionally we are shipping DAB2 Proteins (7) and DAB2 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DAB2 1601 P98082
DAB2 13132 P98078
DAB2 79128 O88797
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-DAB2 Antibodies at antibodies-online.com

Showing 10 out of 84 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of DAB2 Antibody (C-term) (ABIN652936) in A2058 cell line lysates (35 µg/lane). DAB2 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with DAB2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Mouse Rabbit Un-conjugated WB Mouse Dab2 Antibody (C-term) (ABIN1881248) western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the Mouse Dab2 antibody detected the Mouse Dab2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image IHC images using  - Detection of DAB2 by IHC in human papillary carcinoma WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Anti-DAB2 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962649 concentration 41396 ug/ml. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse spleen labeled with Rabbit Anti phospho-DAB2 (Ser24) Polyclonal Antibody, Unconjugated (ABIN1386225) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$291.50
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$379.50
Details

DAB2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , ,
, , ,
,
, , , , , , , , , , , , , ,
Mouse (Murine) , ,


, , , , , , , , , , , , , ,
Rat (Rattus) ,
,

, , , , , , , , , , ,

Top referenced anti-DAB2 Antibodies

  1. Mouse (Murine) Polyclonal DAB2 Primary Antibody for WB - ABIN1881248 : Collaco, Jakab, Hegan, Mooseker, Ameen: Alpha-AP-2 directs myosin VI-dependent endocytosis of cystic fibrosis transmembrane conductance regulator chloride channels in the intestine. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN1881248

  2. Human Polyclonal DAB2 Primary Antibody for FACS, IHC (p) - ABIN652936 : Tseng, Ely, Pong, Wang, Zhou, Hsieh: The role of DOC-2/DAB2 protein phosphorylation in the inhibition of AP-1 activity. An underlying mechanism of its tumor-suppressive function in prostate cancer. in The Journal of biological chemistry 1999 (PubMed)

More Antibodies against DAB2 Interaction Partners

Human Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) interaction partners

  1. Data show that miR106b was frequently up-regulated in human cervical carcinoma tumors and cell lines and inversely correlated with DAB2 expression. Its regulation in under TGF-beta1 (show TGFB1 Antibodies) which contributes to cell migration by targeting DAB2 in cervical carcinoma.

  2. these findings reveal that DAB2 is critical for controlling inflammatory signaling during phenotypic polarization of macrophages

  3. inhibition of WNT (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling by DAB2 is essential for establishing the correct number of cardiomyocytes in the developing heart.

  4. DAB2 regulated the cell migration associated genes in PC3 (show PCSK1 Antibodies) cells, and the differential DAB2 expression between LNCaP and PC3 (show PCSK1 Antibodies) cells was partly regulated by histone 4 acetylation.

  5. Dab2 depletion also increases the rescued protein half-life of DeltaF508 CFTR (show CFTR Antibodies) by ~18% and ~91%, respectively

  6. These results indicated that miR (show MLXIP Antibodies)-93 plays an important role in the initiation and progression of NPC (show NPC1 Antibodies) by targeting Dab2 and the miR (show MLXIP Antibodies)-93/Dab2 pathway may contribute to the development of novel therapeutic strategies for NPC (show NPC1 Antibodies) in the future.

  7. DAB2 expression is decreased in Non-Small Cell Lung Cancer , and the frequent methylation event at sites -86 to 226 of the DAB2 gene could contribute to the downregulation of DAB2.

  8. Attenuating Dab2 expression in K562 cells diminished TfR (show TFRC Antibodies) internalization and increased surface levels of TfR (show TFRC Antibodies) concomitantly with a decrease in Tf uptake and erythroid differentiation.

  9. Results suggest that endogenous Dab2 exacerbates central nervous system inflammation, potentially acting to up-regulate reactive oxygen species expression in macrophages and microglia, and that it is of potential pathogenic relevance in multiple sclerosis

  10. Numb (show NUMB Antibodies) specifically regulates NPC1L1 (show NPC1L1 Antibodies)-mediated cholesterol absorption both in human intestine and liver, distinct from ARH (show LDLRAP1 Antibodies) and Dab2, which selectively participate in LDLR (show LDLR Antibodies)-mediated LDL uptake.

Mouse (Murine) Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) interaction partners

  1. Results identified a novel activation marker, DAB2, which expression is significantly different between microglia activation stages M2a and either M1 or M2b.

  2. these findings reveal that DAB2 is critical for controlling inflammatory signaling during phenotypic polarization of macrophages

  3. Dab2 expression is induced by hormones

  4. Results suggest that endogenous Dab2 exacerbates central nervous system inflammation, potentially acting to up-regulate reactive oxygen species expression in macrophages and microglia, and that it is of potential pathogenic relevance in multiple sclerosis

  5. Disabled-2 is required for efficient hemostasis and platelet activation by thrombin (show F2 Antibodies) in mice.

  6. Akt1 (show AKT1 Antibodies) and Akt2 (show AKT2 Antibodies) are involved in albumin (show ALB Antibodies) endocytosis, and phosphorylation of Dab2 by Akt (show AKT1 Antibodies) induces albumin (show ALB Antibodies) endocytosis in proximal tubule epithelial cells.

  7. Study of dab2 mutant allele in embryos and embryoid bodies confirms a role for Dab2 in extraembryonic endoderm development and epithelial organization. Also, Dab2 has a physiological role in the endocytosis of lipoproteins and cholesterol metabolism.

  8. miR (show MLXIP Antibodies)-145 regulates the migration and invasion of highly invasive prostate cancer cells through targeting DAB2 gene

  9. The authors report that Dab2, previously described as an inhibitor of Wnt/beta-catenin signalling, selectively recruits LRP6 to the clathrin-dependent endocytic route, thereby sequestering it from caveolin-mediated endocytosis.

  10. Data show that although small RNA-mediated Dab2 knockdown had no affect on the internalization of various clathrin-dependent cargo, TGF-beta (show TGFB1 Antibodies) receptor recycling was abrogated.

Cow (Bovine) Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2) interaction partners

  1. Exposure to follicular fluid transiently increased the transcript levels of IL8 (show IL8 Antibodies) and PTGS2 (show PTGS2 Antibodies), and decreased the expression of SOD2 (show SOD2 Antibodies), GPX3 (show GPX3 Antibodies), DAB2, and NR3C1 (show NR3C1 Antibodies). TNF (show TNF Antibodies) and IL6 (show IL6 Antibodies) levels were also decreased while those of NAMPT (show NAMPT Antibodies) were unaffected.

DAB2 Antigen Profile

Protein Summary

This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with DAB2

  • disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (DAB2) antibody
  • disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) (dab2) antibody
  • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (dab2) antibody
  • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (DAB2) antibody
  • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) (Dab2) antibody
  • disabled 2, mitogen-responsive phosphoprotein (Dab2) antibody
  • 5730435J12Rik antibody
  • AA960054 antibody
  • AI957090 antibody
  • D15Wsu122e antibody
  • D630005B22Rik antibody
  • Doc-2 antibody
  • Doc2 antibody
  • p96 antibody

Protein level used designations for DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) , disabled homolog 2 , disabled homolog 2, mitogen-responsive phosphoprotein , disabled homolog 2-like , differentially-expressed protein 2 , mitogen-responsive phosphoprotein , C9 , DOC-2 p82 isoform , disabled homolog 2 mitogen-responsive phosphoprotein

GENE ID SPECIES
461905 Pan troglodytes
694349 Macaca mulatta
100019082 Monodelphis domestica
100066655 Equus caballus
100075899 Ornithorhynchus anatinus
100171587 Pongo abelii
100337568 Xenopus laevis
100411016 Callithrix jacchus
100484738 Ailuropoda melanoleuca
100485591 Xenopus (Silurana) tropicalis
100593149 Nomascus leucogenys
1601 Homo sapiens
100734816 Cavia porcellus
13132 Mus musculus
79128 Rattus norvegicus
427449 Gallus gallus
479353 Canis lupus familiaris
100519746 Sus scrofa
509221 Bos taurus
Selected quality suppliers for anti-DAB2 (DAB2) Antibodies
Did you look for something else?