DAB2 antibody (AA 275-325)

Catalog No. ABIN7449708

The Rabbit Polyclonal anti-DAB2 antibody (ABIN7449708) specifically detects DAB2 in WB and IP. The antibody is reactive with Human samples.

Quick Overview for DAB2 antibody (AA 275-325) (ABIN7449708)

Target: DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-DAB2 Antibody

Binding Specificity: AA 275-325

Purpose: Rabbit anti-Dab2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 275 and 325

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:1,000 - 1:5,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for DAB2

Target: DAB2 (Disabled Homolog 2, Mitogen-Responsive phosphoprotein (Drosophila) (DAB2))

Alternative Name: Dab2

Background: Background: Disabled homolog 2 (Dab2) is an adapter protein that functions as a clathrin-associated sorting protein (CLASP) required for clathrin-mediated endocytosis of selected cargo proteins. Dab2 can bind and assemble clathrin, and binds simultaneously to phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and cargos containing non-phosphorylated NPXY internalization motifs, such as the LDL receptor, to recruit them to clathrin-coated pits [taken from the Universal Protein Resource (UniProt) P98082].

Gene ID: 1601

NCBI Accession: NP_001334

UniProt: P98082

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process