Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
DNAJC10 encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily C, Member 10 Proteins (6) and many more products for this protein.
Showing 10 out of 59 products:
Human Polyclonal DNAJC10 Primary Antibody for ELISA, WB - ABIN565732
Corazzari, Lovat, Armstrong, Fimia, Hill, Birch-Machin, Redfern, Piacentini: Targeting homeostatic mechanisms of endoplasmic reticulum stress to increase susceptibility of cancer cells to fenretinide-induced apoptosis: the role of stress proteins ERdj5 and ERp57. in British journal of cancer 2007
Show all 3 references for ABIN565732
Human Polyclonal DNAJC10 Primary Antibody for WB - ABIN2783736
Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005
ERdj5 is a member of the proteostasis network that regulates rod opsin (show RHO Antibodies) biogenesis and supports a role for disulfide bond formation/reduction in rod opsin (show RHO Antibodies) biogenesis and disease.
ERdj5, by binding to Sel1L (show SEL1L Antibodies), triggers BiP (show GDF10 Antibodies)-Cholera toxin interaction proximal to the Hrd1 (show SYVN1 Antibodies) complex; postulate this scenario enables the Hrd1 (show SYVN1 Antibodies)-associated retrotranslocation machinery to capture the toxin efficiently once the toxin is released from BiP (show GDF10 Antibodies)
ERdj5 acts as the endoplasmic reticulum reductase, both preparing misfolded proteins for degradation and catalyzing the folding of proteins that form obligatory non-native disulfides.
ERdj5 is a ubiquitous protein localized in the ER and is particularly abundant in secretory cells. Its transcription is induced during ER stress, suggesting potential roles for ERdj5 in protein folding and translocation across the ER membrane.
JPDI may have roles in folding of some proteins in the ER, chaperoning by BiP (show GDF10 Antibodies) and formation of proper disulfide bonds
The organization of the functional motifs of hMTHr suggests that the protein might be a member of a molecular chaperone (show HSP90AA1 Antibodies) family.
ERdj4 (show DNAJB9 Antibodies) and ERdj5 promote turnover of misfolded SP-C (show SFTPC Antibodies) and this activity is dependent on their ability to stimulate BiP (show GDF10 Antibodies) ATPase (show DNAH8 Antibodies) activity.
study found that an endoplasmic reticulum (ER) protein ERdj5 had a reductase activity, cleaved the disulfide bonds of misfolded proteins & accelerated ER-associated degradation through its physical and functional associations with EDEM (show EDEM1 Antibodies) & BiP (show GDF10 Antibodies)
ERdj5 decreases neuroblastoma (show ARHGEF16 Antibodies) cell survival by down-regulating the UPR, raising the possibility that this protein could be a target for anti-tumor approaches.
study identified the redox partners of ERdj5 from the mouse epididymis; findings show that ERdj5 interacted with two of the identified proteins via formation of intermolecular disulfide bond
Data suggest that ERdj5 contributes to ER protein quality control in the salivary gland.
JPDI may have roles in folding of some proteins in the ER, chaperoning by BiP (show HSPA5 Antibodies) and formation of proper disulfide bonds
study found that an endoplasmic reticulum (ER) protein ERdj5 had a reductase activity, cleaved the disulfide bonds of misfolded proteins & accelerated ER-associated degradation through its physical and functional associations with EDEM (show EDEM1 Antibodies) & BiP (show HSPA5 Antibodies)
This gene encodes an endoplasmic reticulum co-chaperone which is part of the endoplasmic reticulum-associated degradation complex involved in recognizing and degrading misfolded proteins. The encoded protein reduces incorrect disulfide bonds in misfolded glycoproteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
, DnaJ (Hsp40) homolog, subfamily C, member 10
, dnaJ homolog subfamily C member 10
, ER-resident protein ERdj5
, J-domain-containing protein disulfide isomerase-like protein
, protein disulfide isomerase family A, member 19
, endoplasmic reticulum DnaJ-PDI fusion protein 1
, j domain-containing PDI-like protein
, j domain-containing protein disulfide isomerase-like protein