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anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) Antibodies

DNAJC3 encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. Additionally we are shipping DnaJ (Hsp40) Homolog, Subfamily C, Member 3 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DNAJC3 5611 Q13217
DNAJC3 100037258 Q91YW3
DNAJC3 63880 Q9R0T3
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Top anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, ELISA, WB Immunofluorescence of monoclonal antibody to DNAJC3 on HeLa cell. [antibody concentration 10 ug/ml] Western Blot detection against Immunogen (51.48 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Cow Rabbit Un-conjugated WB Western blot analysis of DnaJC3 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated IF Immunofluorescence of monoclonal antibody to DNAJC3 on HeLa cell (antibody concentration 10 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (51.85 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$375.83
Details
Human Mouse Un-conjugated ICC, ELISA, WB   100 μg Log in to see 8 to 10 Days
$727.83
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

DNAJC3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 Antibodies

  1. Human Monoclonal DNAJC3 Primary Antibody for IF, ELISA - ABIN562442 : Roobol, Roobol, Bastide, Knight, Willis, Smales: p58IPK is an inhibitor of the eIF2? kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacity. in The Biochemical journal 2015 (PubMed)

More Antibodies against DnaJ (Hsp40) Homolog, Subfamily C, Member 3 Interaction Partners

Human DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) interaction partners

  1. p58IPK is a general inhibitor of the eIF2alpha kinases in that it also interacts with GCN2. Thus forced overexpression of cytoplasmic p58 delays eIF2alpha phosphorylation, suppresses GCN2 phosphorylation and prolongs protein synthesis

  2. Loss-of-function DNAJC3 mutations lead to a monogenic, recessive form of diabetes mellitus in humans.

  3. p58 (show CDK11B Antibodies)(IPK) suppresses coxsackievirus B3-induced apoptosis through selective activation of PI3K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway that requires activation of ATF6a (show ATF6 Antibodies) and subsequently upregulates mitofusin 2 (show MFN2 Antibodies).

  4. interplay between p38 (show CRK Antibodies) phosphorylation and p58 (show CDK11B Antibodies)(IPK) upregulation has key roles in modulating ERp29 (show ERP29 Antibodies)-induced cell-growth arrest and survival

  5. the crystal structure of human P58 (show CDK11B Antibodies)(IPK)

  6. Coxsackievirus B3 infection induces apoptosis through downregulation of p58IPK and activation of CHOP (show DDIT3 Antibodies) and SREBP1 (show SREBF1 Antibodies).

  7. Spleen cells from transgenic mice overexpressing (Hu)PKR (show PKLR Antibodies) were studied and compared to those from wild-type mice after drug treatment. Dact (show Actbeta Antibodies)-treated spleen cells were resistant to apoptosis; ConA-treated cells had decreased cell division.

  8. P58 (show CDK11B Antibodies)(IPK) is an important component of a negative feedback loop used by the cell to inhibit eIF2alpha (show EIF2A Antibodies) signaling, and thus attenuate the unfolded protein response.

  9. The study demonstrates that P58 (show CDK11B Antibodies)(IPK) inhibits endoplasmic reticulum (ER) stress and plays an important role in maintaining balance and stability of the ER in human retinal capillary endothelial cells.

Pig (Porcine) DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) interaction partners

  1. Cloning, prokaryotic expression of novel swine gene P58IPK and its polyclonal antibody preparation

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) interaction partners

  1. Chaperone protein p58 (show CDK11B Antibodies)(IPK) is expressed predominantly in retinal ganglion cells (RGC), inner retinal neurons, and the photoreceptor inner segments.

  2. p58IPK is a general inhibitor of the eIF2alpha kinases in that it also interacts with GCN2. Thus forced overexpression of cytoplasmic p58 delays eIF2alpha phosphorylation, suppresses GCN2 phosphorylation and prolongs protein synthesis

  3. combined deletion of ATF6alpha (show ATF6 Antibodies) and the ER cochaperone p58 (show CDK11B Antibodies)(IPK) resulted in synthetic embryonic lethality.

  4. Data present a working model for P58 (show CDK11B Antibodies)(IPK) to act together with Bip (show HSPA5 Antibodies) to prevent protein aggregations and promote protein foldings within ER.

  5. Coxsackievirus B3 infection induces apoptosis through downregulation of p58IPK and activation of CHOP (show DDIT3 Antibodies) and SREBP1 (show SREBF1 Antibodies).

  6. mechanism by which P58 (show CDK11B Antibodies)(IPK) functions to promote protein folding within the endoplasmic reticulum, determined from the crystal structure of P58 (show CDK11B Antibodies)(IPK)

  7. renal injury inflicted by expression of the folding mutants was markedly enhanced by haploinsufficiency of the endoplasmic reticulum cochaperone p58 (show CDK11B Antibodies)(IPK).

  8. The stress of unfolded proteins in the ER activates P58(IPK) transcription through an ER stress-response element in its promoter. P58(IPK) interacts with & inhibits PERK, which protects cells during the ER-stress response by reducing protein synthesis.

  9. Insulin (show INS Antibodies) deficiency associated with the absence of P58 (show CDK11B Antibodies)(IPK) mimics beta-cell failure associated with type 1 and late-stage type 2 diabetes.

  10. absence of P58 (show CDK11B Antibodies)(IPK) led to an increase in eIF2alpha (show EIF2A Antibodies) phosphorylation and decreased influenza virus mRNA translation

DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) Antigen Profile

Protein Summary

This gene encodes a protein with multiple tetratricopeptide repeat (TPR) motifs as well as the highly conserved J domain found in DNAJ chaperone family members. It is a member of the tetratricopeptide repeat family of proteins and acts as an inhibitor of the interferon-induced, dsRNA-activated protein kinase (PKR).

Gene names and symbols associated with DNAJC3

  • DnaJ (Hsp40) homolog, subfamily C, member 3 (dnajc3) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 3 (DNAJC3) antibody
  • DNAJ heat shock N-terminal domain-containing protein (dnajc3) antibody
  • DnaJ (Hsp40) homolog, subfamily C, member 3 (Dnajc3) antibody
  • AA408985 antibody
  • AU067833 antibody
  • cg8286 antibody
  • DDBDRAFT_0186884 antibody
  • DDBDRAFT_0233602 antibody
  • DDB_0186884 antibody
  • DDB_0233602 antibody
  • dnajc3 antibody
  • Dnajc3a antibody
  • Dnajc3b antibody
  • ERdj6 antibody
  • HP58 antibody
  • mp58 antibody
  • p58 antibody
  • p58IPK antibody
  • Prkri antibody
  • wu:fb64f06 antibody
  • zgc:56356 antibody
  • zgc:77731 antibody

Protein level used designations for DNAJC3

dnaJ homolog subfamily C member 3 , DnaJ (Hsp40) homolog, subfamily C, member 3 , Interferon-induced, double-stranded RNA-activated protein kinase inhibitor , TPR repeat-containing protein , endoplasmic reticulum DnaJ protein 6 , interferon-induced, double-stranded RNA-activated protein kinase inhibitor , protein kinase inhibitor of 58 kDa , protein kinase inhibitor p58 , protein-kinase, interferon-inducible double stranded RNA dependent inhibitor , DnaJ (Hsp40) homolog, subfamily C, member 3A , DnaJ (Hsp40) homolog, subfamily C, member 3B , protein kinase, interferon inducible double stranded RNA dependent inhibitor

GENE ID SPECIES
322544 Danio rerio
476966 Canis lupus familiaris
496977 Xenopus (Silurana) tropicalis
695757 Macaca mulatta
736800 Pan troglodytes
8625524 Dictyostelium discoideum AX4
100019766 Monodelphis domestica
100059810 Equus caballus
100393937 Callithrix jacchus
100446513 Pongo abelii
100467911 Ailuropoda melanoleuca
100597711 Nomascus leucogenys
379791 Xenopus laevis
5611 Homo sapiens
286770 Bos taurus
100154166 Sus scrofa
100037258 Mus musculus
63880 Rattus norvegicus
418787 Gallus gallus
Selected quality suppliers for anti-DnaJ (Hsp40) Homolog, Subfamily C, Member 3 (DNAJC3) Antibodies
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