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DNM1 encodes a member of the dynamin subfamily of GTP-binding proteins. Additionally we are shipping Dynamin 1 Kits (37) and Dynamin 1 Proteins (5) and many more products for this protein.
Showing 10 out of 120 products:
Cow (Bovine) Polyclonal Dynamin 1 Primary Antibody for IHC (fro), IF - ABIN372616
Tsuboi, Terakawa, Scalettar, Fantus, Roder, Jeromin: Sweeping model of dynamin activity. Visualization of coupling between exocytosis and endocytosis under an evanescent wave microscope with green fluorescent proteins. in The Journal of biological chemistry 2002
Show all 4 references for ABIN372616
Human Monoclonal Dynamin 1 Primary Antibody for IHC (p), WB - ABIN1107034
Quan, Robinson: Rapid purification of native dynamin I and colorimetric GTPase assay. in Methods in enzymology 2006
Show all 2 references for ABIN1107034
Human Monoclonal Dynamin 1 Primary Antibody for IHC, ELISA - ABIN969087
Yoo, Jeong, Kwon, Hur, Park, Han: Activation of dynamin I gene expression by Sp1 and Sp3 is required for neuronal differentiation of N1E-115 cells. in The Journal of biological chemistry 2002
Show all 2 references for ABIN969087
Cow (Bovine) Polyclonal Dynamin 1 Primary Antibody for WB - ABIN372615
Graham, OCallaghan, McMahon, Burgoyne: Dynamin-dependent and dynamin-independent processes contribute to the regulation of single vesicle release kinetics and quantal size. in Proceedings of the National Academy of Sciences of the United States of America 2002
Show all 2 references for ABIN372615
Cow (Bovine) Polyclonal Dynamin 1 Primary Antibody for WB - ABIN372617
Cousin, Tan, Robinson: Protein phosphorylation is required for endocytosis in nerve terminals: potential role for the dephosphins dynamin I and synaptojanin, but not AP180 or amphiphysin. in Journal of neurochemistry 2001
Chicken Polyclonal Dynamin 1 Primary Antibody for IHC, WB - ABIN2784624
Chugh, Sharma, Hosur: Pockets of short-range transient order and restricted topological heterogeneity in the guanidine-denatured state ensemble of GED of dynamin. in Biochemistry 2007
Equine herpesvirus type 1 pUL56-induced MHC-I endocytosis required dynamin and tyrosine kinase but was independent of clathrin and caveolin-1, the main constituents of the clathrin- and raft/caveola-mediated endocytosis pathways, respectively.
Down-regulation of Dyn1 (show DNM1L Antibodies) activity enhances extracellular Nme1 (show NME1 Antibodies) in human colon tumor cell lines.
Hypoxic down-regulation of constitutive endocytosis is HIF-independent, and involves caveolin-1 (show CAV1 Antibodies)-mediated inhibition of dynamin-dependent, membrane raft endocytosis.
study reports 2 patients with early onset epileptic encephalopathy possessing de novo DNM1 mutations; detected the novel mutation c.127G>A (p.Gly43Ser) in a patient with Lennox-Gastaut syndrome, and a recurrent mutation c.709C>T (p.Arg237Trp) in a patient with West syndrome
The rare variants in DNM1 were significantly associated with smoking status.
Data indicate that stimulation of the dynamin GTPase activity by SH3 domains is determined by its middle domain.
molecular simulations corroborate the bimodal character of dynamin action and indicate radial and axial forces as dominant, although not independent, drivers of hemi-fission and fission membrane- transformations, respectively
Data indicate the dynamics of a dynamin 1-catalysed GTP (show AK3 Antibodies) hydrolysis and tube-severing reaction in real time using fluorescence microscopy.
This study identified and confirmed DNM1 protein changes within the postsynaptic density in schizophrenia.
findings support a role for HTT (show HTT Antibodies) on dynamin 1 function and ER homoeostasis. Proteolysis-induced alteration of this function may be relevant to disease.
CRISPR-Cas9n-mediated knockout and reconstitution studies establish that dynamin-1 is activated by Akt (show AKT1 Antibodies)/GSK3beta (show GSK3b Antibodies) signaling in H1299 non-small lung cancer cells.
Tissue-specific dynamin-1 deletion at the calyx of Held decreases short-term depression through a mechanism distinct from vesicle resupply.
the identification of the oligomerization cycle of dynamin is an attractive potential therapeutic target to treat chronic kidney diseases .
In the developing neurons, there is a dynamin 1-, dynamin 3- and clathrin-independent pathway of synaptic vesicle recycling mediated by bulk endocytosis.
Using an inducible knockout mouse model to generate dynamin 1- and 2-deficient primary osteoclast precursors and myoblasts, it was shown that fusion of both cell types requires dynamin.
Dynamin 1 is required for memory formation.
As low-level expression of the dynamin 3 (show DNM3 Antibodies) gene in these cells could not be excluded, we have now engineered dynamin 1, 2 and 3 triple KO (TKO (show MRPS12 Antibodies)) fibroblasts.
Results further implicate dynamin-1 in vesicular protein transport processes relevant to synaptic and post-Golgi pathways and indicate a possible role in photoreceptor stability
Data indicate that coxsackievirus and adenovirus receptor (show CXADR Antibodies) (CAR) internalization was lipid microdomain-, actin-, and dynamin-dependent, and subsequently followed by CAR degradation in lysosomes.
A missense mutation of dynamin 1 inhibits endocytosis via clathrin-mediated endocytosis.
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described.
, dynamin 1
, dynamin-1-like protein
, dynamin, brain
, dynamin-1-like protein-like