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anti-Dystroglycan 1 (DAG1) Antibodies

Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Additionally we are shipping Dystroglycan Proteins (11) and Dystroglycan Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
DAG1 13138 Q62165
DAG1 1605 Q14118
DAG1 114489  
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Top anti-Dystroglycan Antibodies at antibodies-online.com

Showing 10 out of 97 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Goat Un-conjugated EIA, WB <strong>Western blot analysis:</strong> DAG1 antibody staining of Human Skeletal Muscle lysate at 0.2 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. <strong>Western blot analysis:</strong> DAG1 antibody staining of Mouse and Rat Skeletal Muscle lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DAG1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated IF, WB Western blot analysis of beta-Dystroglycan on a HepG2 cell lysate (Human hepatocellular carcinoma, ATCC HB-8065). Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-human beta-Dystroglycan antibody. 50 μg Log in to see 5 to 6 Days
$205.42
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB DAG1 Antibody (C-term) (ABIN658022) western blot analysis in mouse NIH-3T3 cell line lysates (35 µg/lane). This demonstrates the DAG1 antibody detected the DAG1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB Western blot analysis of beta-Dystroglycan on a HepG2 cell lysate (Human hepatocellular carcinoma, ATCC HB-8065). Lane 1: 1:500, lane 2: 1:1000, lane 3: 1:2000 dilution of the mouse anti-human beta-Dystroglycan antibody. 150 μg Log in to see 5 to 6 Days
$398.54
Details
Cow Mouse Un-conjugated EIA, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$643.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged DAG1 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (37.84 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

DAG1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-Dystroglycan Antibodies

  1. Human Monoclonal Dystroglycan Primary Antibody for ELISA, WB - ABIN395277 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 5 references for ABIN395277

  2. Human Monoclonal Dystroglycan Primary Antibody for WB - ABIN968735 : Ibraghimov-Beskrovnaya, Milatovich, Ozcelik, Yang, Koepnick, Francke, Campbell: Human dystroglycan: skeletal muscle cDNA, genomic structure, origin of tissue specific isoforms and chromosomal localization. in Human molecular genetics 1994 (PubMed)
    Show all 3 references for ABIN968735

  3. Human Monoclonal Dystroglycan Primary Antibody for IF, WB - ABIN968734 : Jacobson, Côté, Rossi, Rotundo, Carbonetto: The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane. in The Journal of cell biology 2001 (PubMed)
    Show all 3 references for ABIN968734

  4. Cow (Bovine) Monoclonal Dystroglycan Primary Antibody for EIA, IHC (p) - ABIN1107039 : Lin, Song, Ding, Liu, Liu, Wong: Facile preparation of nitrogen-doped graphene as a metal-free catalyst for oxygen reduction reaction. in Physical chemistry chemical physics : PCCP 2012 (PubMed)
    Show all 2 references for ABIN1107039

  5. Human Monoclonal Dystroglycan Primary Antibody for ELISA, WB - ABIN560555 : Hesse, Johansson, Mattsson, Bremell, Andreasson, Halim, Anckarsäter, Blennow, Anckarsäter, Zetterberg, Larson, Hagberg, Grahn: The N-terminal domain of ?-dystroglycan, released as a 38 kDa protein, is increased in cerebrospinal fluid in patients with Lyme neuroborreliosis. in Biochemical and biophysical research communications 2011 (PubMed)

  6. Cow (Bovine) Polyclonal Dystroglycan Primary Antibody for EIA, WB - ABIN498078 : de Bernabé, Inamori, Yoshida-Moriguchi, Weydert, Harper, Willer, Henry, Campbell: Loss of alpha-dystroglycan laminin binding in epithelium-derived cancers is caused by silencing of LARGE. in The Journal of biological chemistry 2009 (PubMed)

More Antibodies against Dystroglycan Interaction Partners

Mouse (Murine) Dystroglycan 1 (DAG1) interaction partners

  1. Fktn (show FKTN Antibodies) deficient mice express moderate to severe muscular dystrophy; glycosylated alpha-dystroglycan has a unique role in muscle regeneration in these mice

  2. 5-amino-4-imidazolecarboxamide riboside treatment increases utrophin (show UTRN Antibodies) A and beta-dystroglycan expression in mdx (show DMD Antibodies) mouse muscle.

  3. Phosphorylation within the cysteine-rich region of dystrophin (show DMD Antibodies) enhances its association with beta-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting.

  4. Results suggest that by interfering in the cross-talk between the transmembrane form of the laminin receptor dystroglycan and F-actin, AHNAK1 (show AHNAK Antibodies) influences the cytoskeleton organization of Schwann cells

  5. We evaluate the key characteristics of the mdx in comparison with other mouse mutants with inactivations in DAPC components, along with key modifiers of the disease phenotype.

  6. results indicate a novel role for laminin-dystroglycan interactions in the cooperative integration of astrocytes, endothelial cells, and pericytes in regulating the Blood Brain Barrier.

  7. Endogenous glucuronyltransferase activity of LARGE or LARGE2 (show GYLTL1B Antibodies) required for functional modification of alpha-dystroglycan in cells and tissues.

  8. Beta-dystroglycan can respond to ezrin (show EZR Antibodies) driven cytoskeletal and cell morphology changes,by translocating from the cytoplasm to the nucleus.

  9. Alpha dystroglycan is a perlecan (show HSPG2 Antibodies) receptor that specifically functions in the stellate reticulum of the embryonic stage.

  10. The study provides evidence for at least three separate pools of dystroglycan complexes within myofibers that differ in composition and are differentially affected by loss of dystrophin (show DMD Antibodies).

Human Dystroglycan 1 (DAG1) interaction partners

  1. Phosphorylation within the cysteine-rich region of dystrophin (show DMD Antibodies) enhances its association with beta-dystroglycan and identifies a potential novel therapeutic target for skeletal muscle wasting.

  2. Novel mutations in DAG1 are associated with asymptomatic hyperCKemia with hypoglycosylation of alpha-dystroglycan.

  3. Depletion of DAG resulted in altered morphology and reduced properties of differentiated HL-60 cells, including chemotaxis, respiratory burst, phagocytic activities and markers of differentiation, implicating DAG as a protein involved in differentiation.

  4. A report of a homozygous novel DAG1 missense mutation c.2006G>T in the beta-subunit (show POLG Antibodies) of dystroglycan in two Libyan siblings with with a novel muscle-eye-brain disease-like phenotype with multicystic leucodystrophy.

  5. The study provides evidence for at least three separate pools of dystroglycan complexes within myofibers that differ in composition and are differentially affected by loss of dystrophin (show DMD Antibodies).

  6. These data suggest that proteolysis, tyrosine phosphorylation and translocation of dystroglycan to the nucleus resulting in altered gene transcription could be important mechanisms in the progression of prostate cancer.

  7. T192M point-mutation in dystroglycan leads to a weaker interactions with laminin-1 (show LAMA1 Antibodies), which leads to hypoglycosylation and which finally leads to the limb girdle disease.

  8. GTDC2 (show GTDC2 Antibodies) generates CTD110.6 antibody-reactive N-acetylglucosamine epitopes on the O-mannosylated alpha-dystroglycan.

  9. the Dystroglycan-mediated cortical microtubule anchoring, the disruption of which initiates gastrulation EMT (show ITK Antibodies).

  10. Loss of alpha-dystroglycan and increased CD133 expression are frequent events in human colon cancer and evaluation of CD133 expression could help to identify high-risk colon cancer patients.

Rabbit Dystroglycan 1 (DAG1) interaction partners

  1. Results provide evidence that MMP-2 (show MMP2 Antibodies) bears the potentiality to cleave alpha-DG enriched from rabbit skeletal muscle indicating that this degradation indeed might also occur in vivo.

Dystroglycan (DAG1) Antigen Profile

Protein Summary

Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.

Gene names and symbols associated with anti-Dystroglycan 1 (DAG1) Antibodies

  • dystroglycan 1 (Dag1) antibody
  • dystroglycan 1 (dystrophin-associated glycoprotein 1) (DAG1) antibody
  • dystroglycan 1 (dystrophin-associated glycoprotein 1) (Dag1) antibody
  • dystroglycan-like (LOC100620392) antibody
  • 156DAG antibody
  • A3a antibody
  • AGRNR antibody
  • D9Wsu13e antibody
  • DAG antibody
  • DG antibody
  • Dp71 antibody
  • Dp427 antibody
  • MDDGC7 antibody
  • MDDGC9 antibody
  • RAB7 antibody

Protein level used designations for anti-Dystroglycan 1 (DAG1) Antibodies

alpha-dystroglycan , beta-dystroglycan , dystroglycan , dystrophin associated glycoprotein 1 , dystrophin-associated glycoprotein 1 , glycine cleavage system T-protein , RAB7, member RAS oncogene family

GENE ID SPECIES
13138 Mus musculus
100049058 Gallus gallus
1605 Homo sapiens
101103515 Ovis aries
114489 Rattus norvegicus
476623 Canis lupus familiaris
281439 Bos taurus
100734382 Cavia porcellus
100009278 Oryctolagus cuniculus
100620392 Sus scrofa
Selected quality suppliers for anti-Dystroglycan (DAG1) Antibodies
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