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anti-E1A Binding Protein P400 (EP400) Antibodies

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EP400 57634 Q96L91
EP400 75560 Q8CHI8
EP400 304569  
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Top anti-EP400 Antibodies at antibodies-online.com

Showing 10 out of 11 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Western Blot analysis of EP400 expression in transfected 293T cell line by EP400 monoclonal antibody (M01), clone 2A7.Lane 1: EP400 transfected lysate(105.7 KDa).Lane 2: Non-transfected lysate. Western Blot detection against Immunogen (37.62 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p)   100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IP, PLA, WB   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Mouse Un-conjugated IF, WB Western Blot analysis of EP400 expression in transfected 293T cell line by EP400 MaxPab polyclonal antibody.Lane 1: EP400 transfected lysate(108.35 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to EP400 on HeLa cell. [antibody concentration 10 ug/ml] 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ICC, IF, WB   0.1 mL Log in to see 6 to 9 Days
$452.81
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 11 to 16 Days
$553.14
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Mouse Un-conjugated IF, WB   50 μg Log in to see 8 to 10 Days
$742.50
Details
Human Mouse Un-conjugated IF, WB   50 μg Log in to see 11 to 16 Days
$553.14
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 9 Days
$588.50
Details

EP400 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine) ,


Rat (Rattus) ,


Top referenced anti-EP400 Antibodies

  1. Human Monoclonal EP400 Primary Antibody for ELISA, WB - ABIN528254 : Iwai, Takegami, Shiozaki, Miyazaki: Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP. in PLoS ONE 2011 (PubMed)

More Antibodies against EP400 Interaction Partners

Human E1A Binding Protein P400 (EP400) interaction partners

  1. All together these results show that p400 acts as a brake to prevent alternative End Joining-dependent genetic instability and underline its potential value as a clinical marker.

  2. EP400 deposits H3.3 into chromatin alongside H2AZ and contributes to gene regulation after Pol II pre-initiation complex assembly.

  3. Data indicate that three genes, namely Chemokine (C-X-C motif) receptor 2 (CXCR2 (show CXCR2 Antibodies)), C-C chemokine receptor type 2 (CCR2 (show CCR2 Antibodies)) and E1A-Binding Protein P400 (EP400), were able to identify HCC (show FAM126A Antibodies) individually with accuracies of 82.4%, 78.4% and 65%, respectively.

  4. Our data suggest that the highly proliferative, decreased-p400 subgroup of renal cell carcinomas represents tumors that are characterized by a loss of the tumor-suppressive mechanism of senescence.

  5. age-dependent p400 downregulation and loss of H2A.Z (show H2AFZ Antibodies) localisation may contribute to the onset of replicative senescence through a sustained high rate of p21 (show CDKN1A Antibodies) transcription

  6. The p400 ATPase is (show ATP11A Antibodies) required for DNA repair by homologous recombination.

  7. incorporation of the histone variant H2A.Z (show H2AFZ Antibodies) at the promoter regions of PPARgamma (show PPARG Antibodies) target genes by p400/Brd8 (show BRD8 Antibodies) is essential to allow fat cell differentiation

  8. p400 is a novel DNA damage response protein and p400-mediated alterations in nucleosome and chromatin structure promote both chromatin ubiquitination and the accumulation of brca1 and 53BP1 (show TP53BP1 Antibodies) at sites of DNA damage.

  9. Depletion of p400 indeed increases intracellular reactive oxygen species levels and causes the appearance of DNA damage

  10. Results suggest that p400 represses basal p21 (show CDKN1A Antibodies) gene expression through dual mechanisms that include direct inhibition of TIP60 (show KAT5 Antibodies) and ATP-dependent positioning of H2A.Z (show H2AFZ Antibodies) at the promoter.

Mouse (Murine) E1A Binding Protein P400 (EP400) interaction partners

  1. incorporation of the histone variant H2A.Z (show H2AFZ Antibodies) at the promoter regions of PPARgamma (show PPARG Antibodies) target genes by p400 (show ITPR1 Antibodies)/Brd8 (show BRD8 Antibodies) is essential to allow fat cell differentiation

  2. p400/mDomino plays a key role in cellular proliferation by controlling the expression of cell-cycle-regulatory genes.

  3. p400 (show ITPR1 Antibodies) is a regulator of the ARF (show CDKN2A Antibodies)-p53 (show TP53 Antibodies) pathway and a component of the cellular machinery that couples proliferation to cell death

  4. p400/mDomino plays a critical role in embryonic hematopoiesis by regulating the expression of developmentally essential genes such as those in the Hox (show MSH2 Antibodies) gene cluster.

  5. senescence induced by VHL (show VHL Antibodies) inactivation is a tumour-suppressive mechanism mediated by Rb and p400 (show ITPR1 Antibodies) (and HIF independent) that must be overcome to develop VHL (show VHL Antibodies)-associated neoplasias

  6. These data indicate that Tip60-p400 integrates signals from Nanog and H3K4me3 to regulate gene expression in embryonic stem cells.

EP400 Antigen Profile

Protein Summary

Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400 (By similarity). Regulates transcriptional activity of ZNF42.

Gene names and symbols associated with EP400

  • E1A binding protein p400 (EP400) antibody
  • E1a binding protein P400 (AaeL_AAEL001440) antibody
  • E1a binding protein P400 (CpipJ_CPIJ007689) antibody
  • E1a binding protein P400 (CpipJ_CPIJ007688) antibody
  • E1a binding protein P400 (CpipJ_CPIJ007686) antibody
  • E1a binding protein P400 (CpipJ_CPIJ008061) antibody
  • E1a binding protein P400 (CpipJ_CPIJ009472) antibody
  • E1a binding protein P400 (CpipJ_CPIJ014610) antibody
  • E1a binding protein P400 (CpipJ_CPIJ018817) antibody
  • E1A binding protein p400 (Ep400) antibody
  • 1700020J09Rik antibody
  • AU023439 antibody
  • CAGH32 antibody
  • mDomino antibody
  • mKIAA1498 antibody
  • p400 antibody
  • TNRC12 antibody

Protein level used designations for EP400

E1A binding protein p400 , E1a binding protein P400 , e1A-binding protein p400-like , E1A-binding protein p400 , CAG repeat protein 32 , domino homolog , hDomino , p400 SWI2/SNF2-related protein , p400 kDa SWI2/SNF2-related protein , trinucleotide repeat containing 12 , trinucleotide repeat-containing gene 12 protein

GENE ID SPECIES
738562 Pan troglodytes
5570719 Aedes aegypti
6040121 Culex quinquefasciatus
6040124 Culex quinquefasciatus
6040143 Culex quinquefasciatus
6040789 Culex quinquefasciatus
6042283 Culex quinquefasciatus
6047810 Culex quinquefasciatus
6052761 Culex quinquefasciatus
100451130 Pongo abelii
486227 Canis lupus familiaris
538310 Bos taurus
57634 Homo sapiens
75560 Mus musculus
304569 Rattus norvegicus
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