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Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. Additionally we are shipping and many more products for this protein.
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Human Polyclonal EVI5 Primary Antibody for EIA, WB - ABIN952136
Jacob, Osato, Yamashita, Wang, Taniuchi, Littman, Asou, Ito: Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis. in Blood 2010
Show all 2 references for ABIN952136
EVI5 as a strong candidate disease risk gene in the 1p22.1 multiple sclerosis risk locus
Data show that heat shock transcription factor 1 (show HSF1 Antibodies)/miR (show MLXIP Antibodies)-135b/reversion-inducing-cysteine-rich protein with kazal motifs (show RECK Antibodies) and ecotropic viral integration site 5 axis provides novel insight into the mechanisms of hepatocellular carcinoma metastasis.
in HLA-DRB1 (show HLA-DRB1 Antibodies) positive patients, EVI5 was associated with attacks of greater severity and worse recovery in Multiple sclerosis .
cellular functions exhibited by the Evi5 family members
An analysis and fine mapping of GFI-EVI5-RPL5-FAM69A locus, genotyping eight Tag-single nucleotide polymorphisms in 732 multiple sclerosis patients and 974 controls from Spain, was performed.
Stem cell exhaustion due to Runx1 (show RUNX1 Antibodies) deficiency is prevented by Evi5 activation in leukemogenesis.
a novel centrosomal protein with a complex expression pattern and subcellular localization, possibly involved in centrosome stability and dynamics
Data provide evidence that EVI5 is an essential component of the protein machinery facilitating the final stages of cell septation at the end of mitosis.
Evi5 is a Rab11 binding protein (show WDR44 Antibodies) and that Evi5 may cooperate with Rab11 (show RAB11A Antibodies) to coordinate vesicular trafficking, cytokinesis, and cell cycle control independent of GTPase-activating protein (show RASA1 Antibodies) function
EVI5 is a risk gene for multiple sclerosis.
GFI1B (show GFI1B Antibodies), EVI5, MYB (show MYB Antibodies) are additional mouse genes that cooperate with the human BCL6 (show BCL6 Antibodies) gene to promote the development of lymphomas.
Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis.
ecotropic viral integration site 5
, ecotropic viral integration site 5 protein homolog
, dJ846D11.1 (ecotropic viral integration site 5)
, neuroblastoma stage 4S gene protein
, ecotropic viral integration site 5 protein