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Ecto-NOX Disulfide-Thiol Exchanger 2 Proteins (ENOX2)

The protein encoded by ENOX2 is a growth-related cell surface protein. Additionally we are shipping ENOX2 Antibodies (49) and ENOX2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ENOX2 10495 Q16206
ENOX2 209224 Q8R0Z2
Rat ENOX2 ENOX2 302817  
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Top ENOX2 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

ENOX2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2) Interaction Partners

Human Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2) interaction partners

  1. The results suggest that phosphorylation of serine-504 by PKCdelta (show PKCd Proteins) modulates the biological function of tNOX.

  2. this result suggests that hnRNP F (show HNRNPF Proteins) directs formation of the exon 4 minus variant of ENOX2.

  3. increased NADH levels resulting from ENOX2 inhibition result in decreased prosurvival sphingosine-1-phosphate and increased proapoptotic ceramide, both of which may be important to initiation of the ENOX2 inhibitor-induced apoptotic cascade.

  4. ENOX2 is a dimeric protein containing 4 coppers/dimer capable of carrying out concerted four electron transfers from NADH or ubiquinol to molecular oxygen as required to form water.

  5. tNOX is both necessary and sufficient for the cellular anticancer activities attributed to both EGCg and capsaicin. *tNOX enzyme

  6. results indicate that shRNA targeting of tNOX inhibits the growth of cervical cancer cells, and reduces cell migration via a decrease in the membrane association of Rac (show AKT1 Proteins).

  7. A relationship of tNOX to unregulated growth of cancer cells was provided by data where growth of HeLa cells was inhibited by transfection with the exon 5 antisense oligonucleotides

  8. These results indicate that tNOX is suppressed during apoptosis and demonstrate that tNOX down-regulation sensitizes cells to stress-induced growth reduction, suggesting that tNOX is required for transformed cell growth.

Mouse (Murine) Ecto-NOX Disulfide-Thiol Exchanger 2 (ENOX2) interaction partners

  1. Elevated nox2 (show CYBB Proteins) activity contributes to oxidative stress and cell death in Huntington's disease.

  2. this result suggests that hnRNP F (show HNRNPF Proteins) directs formation of the exon 4 minus variant of ENOX2

  3. Data show that growth of transgenic mouse embryonic fibroblasts overexpressing tNOX is inhibited by low concentrations of the anticarcinogenic tNOX inhibitors epigallocatechin-3-gallate and phenoxodiol.

  4. The tissue expression of tNOX mRNA was greatest in heart, lung and liver. When these tissues were analyzed for cell size.

ENOX2 Protein Profile

Protein Summary

The protein encoded by this gene is a growth-related cell surface protein. It was identifed because it reacts with the monoclonal antibody KI in cells, such as the ovarian carcinoma line OVCAR-3, also expressing the CAKI surface glycoprotein. The encoded protein has two enzymatic activities: catalysis of hydroquinone or NADH oxidation, and protein disulfide interchange. The two activities alternate with a period length of about 24 minutes. The encoded protein also displays prion-like properties. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ENOX2

  • ecto-NOX disulfide-thiol exchanger 2 (ENOX2)
  • ecto-NOX disulfide-thiol exchanger 2 (enox2)
  • ecto-NOX disulfide-thiol exchanger 2 (LOC100222669)
  • ecto-NOX disulfide-thiol exchanger 2 (LOC100348937)
  • ecto-NOX disulfide-thiol exchanger 2 (Enox2)
  • APK1 protein
  • Cova1 protein
  • RGD1563643 protein
  • tNOX protein

Protein level used designations for ENOX2

ecto-NOX disulfide-thiol exchanger 2 , cytosolic ovarian carcinoma antigen 1 , ENOX2 protein-like , APK1 antigen , tumor-associated hydroquinone oxidase

GENE ID SPECIES
422142 Gallus gallus
517820 Bos taurus
566327 Danio rerio
703816 Macaca mulatta
100022116 Monodelphis domestica
100058391 Equus caballus
100222669 Taeniopygia guttata
100348937 Oryctolagus cuniculus
100434273 Pongo abelii
100478148 Ailuropoda melanoleuca
100540023 Meleagris gallopavo
100580372 Nomascus leucogenys
10495 Homo sapiens
209224 Mus musculus
302817 Rattus norvegicus
481050 Canis lupus familiaris
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