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Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.. Additionally we are shipping ETV5 Antibodies (100) and many more products for this protein.
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ERM proteins contribute toward accelerated CD44 (show CD44 Proteins) shedding by MT1-MMP (show MMP14 Proteins) through ERM protein-mediated interactions between their cytoplasmic tails.
Our results reveal a novel ERM-based spatial mechanism that is coopted by DLBCL cells to sustain tumor cell growth and survival.
Increase of ETV5 protein expression is associated with endometrial cancer invasion.
developed a novel RNA in situ hybridization-based assay for the in situ detection of ETV1 (show ETV1 Proteins), ETV4 (show ETV4 Proteins), and ETV5 in formalin-fixed paraffin-embedded tissues from prostate needle biopsies, prostatectomy, and metastatic PCa (show FLVCR1 Proteins) specimens using RNA probes
Snail (show SNAI1 Proteins) regulates the motility and invasiveness of oral cancer cells via RhoA (show RHOA Proteins)/Cdc42 (show CDC42 Proteins)/p-ERM pathway.
there is a higher expression of ERM/ETV5 in early stages of endometrioid endometrial carcinomas
we found that the downregulation of ETV5 reduced the expression of the oncogenic transcription factor FOXM1 (show FOXM1 Proteins).
This data suggests that ETV5 has a significant role in regulating MMP2 (show MMP2 Proteins) expression and therefore matrix resorption in human chondrosarcoma, and thus may be a targetable upstream effector of the metastatic cascade in this cancer.
Review evidence for a role of ETV1 (show ETV1 Proteins), 4 and 5 as oncoproteins and describe modes of their action.
we propose ETV5-transcriptional regulation of the EMT (show ITK Proteins) process through a crosstalk with the tumor surrounding microenvironment, as a principal event initiating EC invasion.
etv5a and etv4 (show ETV4 Proteins) have roles in mediating epithelial cell fate during zebrafish kidney development
Zebrafish etv5a is essential for the inhibition of ventral mesoderm cell proliferation and for the formation of the hemato-vascular lineage.
Further investigations identified Pak1 (show PAK1 Proteins)-ERM as a downstream signaling cascade upon Rac1 activation in the luminal epithelium necessary for uterine receptivity...Rac1 via P38 MAPK (show MAPK14 Proteins) signaling ensures timely epithelial apoptotic death at postimplantation.
The data of this study suggested that the obesity-associated transcription factor ETV5 normally acts to diminish circulating glucocorticoids.
ETS-related transcription factors ETV4 (show ETV4 Proteins) and ETV5 are involved in proliferation and induction of differentiation-associated genes in embryonic stem (ES) cells.
Noise-decreased levels of ROCK2 results in reduction of phosphorylation of ERM that leads to depolymerization of actin filaments
The transcription factors Etv5 and STAt3 (show STAT3 Proteins) control TH17 cell development and allergic airway inflammation.
A missense mutation in the transcription factor ETV5 leads to sterility, increased embryonic and perinatal death, postnatal growth restriction, renal asymmetry and polydactyly in the mouse.
Mouse germline stem (GS) cell transfected with an activated form of Map2k1 (show MAP2K1 Proteins) have upregulated Etv5 and Bcl6b (show BCL6B Proteins) gene expression.
found to be a critical downstream regulator of glial cell line-derived neurotrophic factor (show GDNF Proteins)-signaling that mediated the expression of several known spermatogonial stem cell self-renewal related genes
Results suggest that Etv5 is important for the developmental competence of germ cells and the regulation of responses to steroid hormones in female mice.
Data show that miR (show MLXIP Proteins)-21 is regulated by the transcription factor ETV5, known to be critical for SSC (show CYP11A1 Proteins) self-renewal.
Binds to DNA sequences containing the consensus nucleotide core sequence GGAA.
ETS translocation variant 5
, ets-related molecule
, ets-related protein ERM
, ets variant gene 5 (ets-related molecule)
, ets domain protein