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EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002 [PubMed 12133843]).[supplied by OMIM, Mar 2008].. Additionally we are shipping EIF2A Kits (11) and EIF2A Proteins (6) and many more products for this protein.
Showing 10 out of 76 products:
Human Polyclonal EIF2A Primary Antibody for EIA, FACS - ABIN952042
Willis, Patel, Xiang, Shisler: The effect of the vaccinia K1 protein on the PKR-eIF2alpha pathway in RK13 and HeLa cells. in Virology 2009
Show all 6 references for ABIN952042
Human Polyclonal EIF2A Primary Antibody for FACS, IHC (p) - ABIN653474
Spurgeon, Ornelles: The adenovirus E1B 55-kilodalton and E4 open reading frame 6 proteins limit phosphorylation of eIF2alpha during the late phase of infection. in Journal of virology 2009
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Human Monoclonal EIF2A Primary Antibody for FACS, IHC - ABIN1724933
Schewe, Aguirre-Ghiso: Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy. in Cancer research 2009
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Human Monoclonal EIF2A Primary Antibody for ICC, FACS - ABIN1724939
Yerlikaya, DoKudur: Investigation of the eIF2alpha phosphorylation mechanism in response to proteasome inhibition in melanoma and breast cancer cells. in Molekuliarnaia biologiia 2010
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Chicken Polyclonal EIF2A Primary Antibody for IHC, WB - ABIN2776588
Su, Wang, Baltzis, Qu, Wong, Koromilas: Tyrosine phosphorylation acts as a molecular switch to full-scale activation of the eIF2alpha RNA-dependent protein kinase. in Proceedings of the National Academy of Sciences of the United States of America 2006
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Human Monoclonal EIF2A Primary Antibody for ELISA, WB - ABIN529535
Rojas, Arias, López: Protein kinase R is responsible for the phosphorylation of eIF2alpha in rotavirus infection. in Journal of virology 2010
Thus, during addiction, cocaine hijacks translational control by p-eIF2alpha, initiating synaptic potentiation and addiction-related behaviors.
in mouse skeletal muscle stem cells, general repression of translation, mediated by the phosphorylation of translation initiation factor eIF2alpha at serine 51 (P-eIF2alpha), is required to maintain the quiescent state
Skeletal muscle-specific (show EIF3K Antibodies) eukaryotic translation initiation factor 2alpha (show EIF2S1 Antibodies) phosphorylation controls amino acid metabolism and fibroblast growth factor 21 (show FGF21 Antibodies)-mediated non-cell-autonomous energy metabolism.
These experiments connect embryonic stem cell growth factors to eIF2alpha phosphorylation.
PGRN (show GRN Antibodies) is a key regulator of insulin (show INS Antibodies) resistance and PGRN (show GRN Antibodies) may mediate its effects, at least in part, by inducing ER stress via the PERK (show EIF2AK3 Antibodies)-eIF2alpha dependent pathway
The CARE-LUC mouse model represents an innovative tool to investigate the eIF2alpha-ATF4 (show ATF4 Antibodies) axis and to develop drugs targeting this important pathway in the remediation of related pathologies.
inhibition of eIF2alpha and FAK (show PTK2 Antibodies) signaling may play an important role in cigarette smoking-induced lung EC apoptosis and emphysema
eIF2a phosphorylation is required for the normal function of intestinal Paneth cells and mucosal homeostasis.
Hypothalamic eIF2alpha phosphorylation could play a critical role in the onset of anorexia associated with certain diseases.
The pathogenesis of cardiomyopathy in Frederich ataxia (show USP14 Antibodies) correlates with the early and persistent eIF2alpha phosphorylation.
Both DrPKZ-A and DrPKZ-B isoforms functionally interact with eIF2alpha and inhibit protein synthesis in Danio rerio.
GHRH (show GHRH Antibodies) and GHRH-R (show GHRHR Antibodies) loops are involved in placental choriocarcinoma cell line viability and apoptosis through Akt (show AKT1 Antibodies) and eIF2a (show EIF2S1 Antibodies) pathways.
These findings suggest that phosphorylated-eIF2alpha regulates synaptic actions of nicotine in both mice and humans, and that reduced phosphorylated-eIF2alpha may enhance susceptibility to nicotine (and other drugs of abuse) during adolescence.
The results suggest that dephosphorylation of eIF2a (show EIF2S1 Antibodies) by GADD34 (show PPP1R15A Antibodies) plays an important role in doxorubicin resistance of MCF-7/ADR (show AKR1B1 Antibodies) cells.
The Newcastle disease virus-induced translation shutoff at late infection times was attributed to sustaining phosphorylation of eIF2a (show EIF2S1 Antibodies), which is mediated by continual activation of PKR (show PKLR Antibodies) and degradation of PP1 (show PPA1 Antibodies).
We identified EIF2A (show EIF2S1 Antibodies) phosphorylation as a novel early molecular event occurring in response to NAMPT (show NAMPT Antibodies) inhibition and mediating protein synthesis arrest.
analysis of the ER stress response in immunogenic cell death and the potential value of eIF2alpha phosphorylation as a biomarker for this clinically relevant variant of apoptosis [review]
The data highlight independent interactions of PP1 (show PPA1 Antibodies) and eIF2alpha with GADD34 (show PPP1R15A Antibodies), demonstrating that GADD34 (show PPP1R15A Antibodies) functions as a scaffold both in vitro and in cells
hypusine-eIF5A (show EIF5 Antibodies)-facilitated translation elongation promotes arsenite-induced polysome disassembly and stress granule assembly in cells subjected to adverse environmental conditions
There was no statistically significant difference in IFN therapeutic effectiveness among the patients with different genotypes of eIF-2a (show EIF2S1 Antibodies)-reg2 (show FLOT1 Antibodies).
EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al., 2002
eukaryotic translation initiation factor 2A, 65kDa
, eukaryotic translation initiation factor
, eukaryotic translation initiation factor 2A-like
, 65 kDa eukaryotic translation initiation factor 2A
, eukaryotic translation initiation factor 2A