anti-Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) Antibodies

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. Additionally we are shipping EIF4G2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
EIF4G2 1982 P78344
EIF4G2 13690 Q62448
EIF4G2 361628  
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Top anti-EIF4G2 Antibodies at antibodies-online.com

Showing 10 out of 118 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-EIF4G2 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-EIF4G2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate <b>Sample Type: </b>1. IAH30 cells (0.5x10<sup>6 </sup>cells loaded)<br>2. DF-1 cells (0.5x10<sup>6 </sup>cells loaded)<br><b>Primary Dilution:</b> 1:1000 <br><b>Secondary Antibody</b>: Goat anti-rabbit IgG (whole molecule) peroxidase <br><b>Secondary Dilution:</b>1:10,000 <br><b>Image Submitted By:</b> Yongxiu Yao<br>Institute for Animal Health <b><br></b> 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, WB Flow Cytometry: DAP5 Antibody (39C534.1) [ABIN2659439] - Intracellular flow cytometric staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. 0.1 mg Log in to see 7 to 9 Days
$381.94
Details
Cow Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of EIF4G2 staining in HeLa cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of EIF4G2 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated WB EIF4G2 monoclonal antibody (M01), clone 3B5. Western Blot analysis of EIF4G2 expression in PC-12. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded human skeletal muscle , using DAP5, antibody(10 μg/ml). WB Image Sample(30 μg of whole cell lysate) A:A431, 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image DAP5 antibody [C2C3], C-term detects DAP5 protein at cytosol on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. DAP5 antibody [C2C3], C-term , dilution: 1:500. WB Image Sample (30 ug of whole cell lysate) A: Hela B: Hep G2 , 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from A549 cells, using EIF4G2 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, IF, IHC, WB Western Blot (WB) analysis of specific cells using DAP-5 Polyclonal Antibody. 100 μL Log in to see 16 Days
$175.80
Details

EIF4G2 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-EIF4G2 Antibodies

  1. Human Polyclonal EIF4G2 Primary Antibody for WB - ABIN1944751 : Imataka, Olsen, Sonenberg: A new translational regulator with homology to eukaryotic translation initiation factor 4G. in The EMBO journal 1997 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal EIF4G2 Primary Antibody for IHC (p), ELISA - ABIN560721 : Katsogiannou, Andrieu, Baylot, Baudot, Dusetti, Gayet, Finetti, Garrido, Birnbaum, Bertucci, Brun, Rocchi: The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets. in Molecular & cellular proteomics : MCP 2014 (PubMed)

  3. Human Monoclonal EIF4G2 Primary Antibody for FACS, WB - ABIN265943 : Levy-Strumpf, Deiss, Berissi, Kimchi: DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death. in Molecular and cellular biology 1997 (PubMed)
    Show all 6 Pubmed References

More Antibodies against EIF4G2 Interaction Partners

Zebrafish Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

Xenopus laevis Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

Human Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

  1. DAP5 knockdown from human ESCs (show NR2E3 Antibodies) (hESCs) resulted in persistence of pluripotent gene expression, delayed induction of differentiation-associated genes in different cell lineages, and defective embryoid body formation

  2. Data show that microRNA miR (show MLXIP Antibodies)-379 potentiated lung cancer (LCa (show CLTA Antibodies)) chemosensitivity via modulation of cisplatin (CDDP)-induced apoptosis by directly targeting the eukaryotic translation initiation factor 4 gamma 2 (EIF4G2) 3' UTR (show UTS2R Antibodies).

  3. These results indicate that miR (show MLXIP Antibodies)-139 is capable of inhibiting chondrocyte proliferation and migration, thus being a possible therapeutic target for OA. The mechanism of miR (show MLXIP Antibodies)-139 in chondrocytes may be related to its regulation on EIF4G2 and IGF1R (show IGF1R Antibodies).

  4. The Coxsackievirus B3 protease 2A-mediated cleavage of DAP5 results in the production of two truncates that exert differential effects on protein translation of the IRES-containing genes, leading to enhanced host cell death.

  5. Knockdown of EIF4G2 recapitulated the effects of mir (show MLXIP Antibodies)-139, whereas restoring EIF4G2 expression rescued the mir (show MLXIP Antibodies)-139 phenotype. elevated miR (show MLXIP Antibodies)-139-5p expression is associated with a favorable outcome in acute myeloid leukemia (show BCL11A Antibodies).

  6. findings provide the first mechanistic insights into the function of DAP5 as a selective regulator of cap-independent translation

  7. Our results provide evidence that the tumor suppressor effect of miR (show MLXIP Antibodies)-520c-3p is mediated through repression of translation while inducing senescence and that eIF4GII (show EIF4G3 Antibodies) is a key effector of this anti-tumor activity.

  8. DAP5, a translation initiation factor shown to positively regulate the translation of various internal ribosome entry sites containing mRNAs, promotes internal ribosome entry site-driven translation of p53 (show TP53 Antibodies) mRNA.

  9. DAP5/p97 and DAP5/p86 enhanced the translation of the anti-apoptotic protein Bcl-2 (show BCL2 Antibodies) and inhibited cisplatin-induced apoptosis

  10. Multiple isoforms of eIF4GII (show EIF4G3 Antibodies) arise from multiple promoters & alternative splicing events. A non-canonical CUG initiation codon extends the eIF4GII (show EIF4G3 Antibodies) N-terminus. The eIF4GII (show EIF4G3 Antibodies) N-terminus plays an alternative role in initiation factor assembly.

Mouse (Murine) Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2) interaction partners

  1. analysis of the tandem MA-3 (show PDCD6 Antibodies) region of Pdcd4 (show PDCD4 Antibodies) protein and characterization of its interactions with eIF4A (show EIF4A1 Antibodies) and eIF4G (show EIF4G1 Antibodies)

EIF4G2 Antigen Profile

Protein Summary

Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3\; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

Gene names and symbols associated with EIF4G2

  • eukaryotic translation initiation factor 4, gamma 2b (eif4g2b) antibody
  • eukaryotic translation initiation factor 4 gamma, 2 (EIF4G2) antibody
  • eIF4G-related protein NAT1 (nat1) antibody
  • eukaryotic translation initiation factor 4, gamma 2 (Eif4g2) antibody
  • AA589388 antibody
  • AAG1 antibody
  • DAP-5 antibody
  • DAP5 antibody
  • E130105L11Rik antibody
  • EIF4G2 antibody
  • hm:zeh1307 antibody
  • Nat1 antibody
  • NAT1B antibody
  • Natm1 antibody
  • P97 antibody
  • wu:fa14h01 antibody
  • wu:fb44h01 antibody
  • wu:fb59c06 antibody
  • wu:fc21b05 antibody

Protein level used designations for EIF4G2

eukaryotic translation initiation factor 4 gamma, 2 , fb44h01 , eukaryotic translation initiation factor 4 gamma 2 , Eukaryotic translation initiation factor 4 gamma 2 , DAP-5 , aging-associated protein 1 , death-associated protein 5 , eIF-4-gamma 2 , eIF-4G 2 , eIF4G 2 , eukaryotic translation initiation factor 4G-like 1 , eIF4G-related protein NAT1 , p97 , novel APOBEC-1 target 1 , translation repressor NAT1 , translation repressor Nat1

GENE ID SPECIES
334618 Danio rerio
466443 Pan troglodytes
705510 Macaca mulatta
100173304 Pongo abelii
496405 Xenopus laevis
1982 Homo sapiens
395905 Gallus gallus
476854 Canis lupus familiaris
286870 Bos taurus
100009236 Oryctolagus cuniculus
13690 Mus musculus
361628 Rattus norvegicus
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