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Eukaryotic Translation Initiation Factor 4E Family Member 2 Proteins (EIF4E2)

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.. Additionally we are shipping Eukaryotic Translation Initiation Factor 4E Family Member 2 Antibodies (106) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
EIF4E2 9470 O60573
Rat EIF4E2 EIF4E2 363275  
EIF4E2 26987 Q8BMB3
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Top Eukaryotic Translation Initiation Factor 4E Family Member 2 Proteins at antibodies-online.com

Showing 4 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
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HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

EIF4E2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) Interaction Partners

Human Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) interaction partners

  1. Tristetraprolin (show ZFP36 Proteins) recruits eukaryotic initiation factor (show EIF4G1 Proteins) 4E2 (eIF4E2) to repress target mRNA translation.

  2. DNA damage induces an increase in ARIH1 protein levels and association of ARIH1 with 4EHP. In turn, this causes 4EHP recruitment to the mRNA cap, where it is known to compete with eIF4E.

  3. provide evidence that eIF4E2 binds 4E-T (show EIF4ENIF1 Proteins) in the yeast two hybrid assay, as well as in pull-down assays and by recruitment to P-bodies in mammalian cells

  4. Activation of eIF4E2-directed translation is essential for cancer cells.

  5. GIGYF2 and the zinc finger protein 598 (ZNF598) are identified as components of the 4EHP complex.

  6. 4EHP over-expression instigates a negative feedback loop that inhibits upstream signaling to 4E-BP1 (show EIF4EBP1 Proteins) and ribosomal protein S6 kinase 1 (S6K1 (show RPS6KB1 Proteins)) whereas the 4E-BP1 (show EIF4EBP1 Proteins)-binding-deficient mutant of 4EHP(W95A) was unable to trigger this feedback loop

  7. ISGylation of 4EHP may play an important role in cap structure-dependent translation control in immune responses.

  8. 4EHP plays a physiological role utilizing both cap-binding and protein-binding functions but which is distinct from eIF4E (show EIF4E Proteins).

  9. 4EHP binds cap analogs m(7)GpppG and m(7)GTP (show AK3 Proteins) with low affinity

Mouse (Murine) Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) interaction partners

  1. DNA damage induces an increase in ARIH1 protein levels and association of ARIH1 with Eif4e2. In turn, this causes Eif4e2 recruitment to the mRNA cap, where it is known to compete with eIF4E (show EIF4E Proteins).

  2. Data show that Prep1 and 4EHP co-localize in the cytosol of growing mouse oocytes, and that Prep1 binds the Hoxb4 (show HOXB4 Proteins) 3'UTR to inhibit its translation.[4EHP]

Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2) Protein Profile

Protein Summary

Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Gene names and symbols associated with EIF4E2

  • eukaryotic translation initiation factor 4E family member 2 (EIF4E2)
  • eukaryotic translation initiation factor 4E family member 2 (eif4e2)
  • eukaryotic translation initiation factor 4E member 2 (eif4e2)
  • eukaryotic translation initiation factor 4E family member 2 (LOC100221090)
  • eukaryotic translation initiation factor 4E family member 2 (Eif4e2)
  • eukaryotic translation initiation factor 4E member 2 (Eif4e2)
  • 4E-LP protein
  • 4EHP protein
  • 2700069E09Rik protein
  • AI036339 protein
  • AV129531 protein
  • D0H0S6743E protein
  • EIF4E2 protein
  • Eif4el3 protein
  • id:ibd1007 protein
  • IF4e protein
  • MGC115622 protein
  • zgc:110542 protein
  • zgc:158544 protein

Protein level used designations for EIF4E2

eukaryotic translation initiation factor 4E member 2 , eukaryotic translation initiation factor 4E-like 3 , eukaryotic translation initiation factor 4E family member 2 , eif4E-2A , eukaryotic translation initiation factor 4E type 2 , uncharacterized protein LOC575773 , eIF-4E type 2 , eIF4E type 2 , eIF4E-like cap-binding protein , eIF4E-like protein 4E-LP , eukaryotic translation initiation factor 4E homologous protein , mRNA cap-binding protein 4EHP , mRNA cap-binding protein type 3 , eukaryotic translation initiation factor 4E like 3 , eIF4E-2 , mRNA cap-binding protein type 2

GENE ID SPECIES
424941 Gallus gallus
460015 Pan troglodytes
488481 Canis lupus familiaris
541523 Danio rerio
548830 Xenopus (Silurana) tropicalis
575773 Strongylocentrotus purpuratus
713487 Macaca mulatta
734605 Xenopus laevis
781731 Bos taurus
100173976 Pongo abelii
100221090 Taeniopygia guttata
9470 Homo sapiens
100101924 Sus scrofa
519920 Bos taurus
363275 Rattus norvegicus
610238 Canis lupus familiaris
26987 Mus musculus
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