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F-Box and WD Repeat Domain Containing 2 Proteins (FBXW2)

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Additionally we are shipping FBXW2 Antibodies (42) and FBXW2 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
FBXW2 26190 Q9UKT8
FBXW2 311881 B2RZ17
FBXW2 30050  
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Top FBXW2 Proteins at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,274.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,274.33
Details

FBXW2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Rat (Rattus)

Mouse (Murine)

More Proteins for F-Box and WD Repeat Domain Containing 2 (FBXW2) Interaction Partners

Human F-Box and WD Repeat Domain Containing 2 (FBXW2) interaction partners

  1. RACK1 (show GNB2L1 Proteins) competes with GCM1 (show GCM1 Proteins) for FBW2 and thereby prevents GCM1 (show GCM1 Proteins) ubiquitination, which is also supported by the observation that GCM1 (show GCM1 Proteins) is destabilized in RACK1 (show GNB2L1 Proteins)-knockdown BeWo placental cells

  2. the SCF(hFBW2) E3 complex has a key role in targeting hGCMa to the ubiquitin-proteasome degradation system

  3. UBE2D2 (show UBE2D2 Proteins) is required for GCMa (show GCM1 Proteins) ubiquitination and for association with the SCF (show KITLG Proteins)(FBXW2) complex.

FBXW2 Protein Profile

Protein Summary

F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats.

Gene names and symbols associated with FBXW2

  • F-box and WD repeat domain containing 2 (FBXW2)
  • F-box and WD repeat domain containing 2 (fbxw2)
  • F-box and WD repeat domain containing 2 (Fbxw2)
  • F-box and WD-40 domain protein 2 (Fbxw2)
  • 2700071L08Rik protein
  • FBW2 protein
  • FBXW2 protein
  • Fwd2 protein
  • MD6 protein
  • MGC53244 protein
  • wu:fc72f10 protein
  • zgc:110365 protein

Protein level used designations for FBXW2

F-box and WD repeat domain containing 2 , F-box and WD-40 domain protein 2 , F-box and WD-40 domain-containing protein 2 , F-box/WD repeat-containing protein 2

GENE ID SPECIES
100067698 Equus caballus
464698 Pan troglodytes
496598 Xenopus (Silurana) tropicalis
26190 Homo sapiens
311881 Rattus norvegicus
610990 Canis lupus familiaris
100155830 Sus scrofa
767863 Bos taurus
553942 Danio rerio
380189 Xenopus laevis
417088 Gallus gallus
100339343 Oryctolagus cuniculus
100723973 Cavia porcellus
101122758 Ovis aries
30050 Mus musculus
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